Abstracts tagged "UVB"

Abstract Number: 0538 • ACR Convergence 2021
Strengthening Nuclear Envelope Ameliorates UVB-triggered Skin Inflammation and Kidney Damage in Lupus Mice
Xing Lyu¹, Minghui Li², Ping L Zhang³, Victoria Werth⁴ and Ming-Lin Liu⁴, ¹Tianjin Medical University General Hospital, Philadelphia, PA, ²Tianjin Medical University General Hospital, Tianjin, China (People's Republic), ³Division of Anatomic Pathology,Beaumont Laboratories, Beaumont Health, Royal Oak, MI, ⁴University of Pennsylvania, Philadelphia, PA
Background/Purpose: Ultraviolet B (UVB) exposure triggers lupus flare by worsening skin lesions and systemic symptoms such as lupus nephritis. The effects of UVB-induced skin inflammation…
Abstract Number: 0999 • ACR Convergence 2021
UVB-irradiated Keratinocyte-derived Extracellular Vesicles Induced Proinflammatory Responses in Macrophages
Yubin Li¹, Thomas Vazquez², DeAnna Diaz³, Mariko Momohara⁴ and Victoria Werth⁴, ¹Corporal Michael J. Crescenz VAMC, Department of Dermatology, U Penn, Philadelphia, PA, ²FIU Wertheim College of Medicine, Virginia Beach, VA, ³Philadelphia College of Medicine, Philadelphia, PA, ⁴University of Pennsylvania, Philadelphia, PA
Background/Purpose: Ultraviolet B irradiation (UVB) contributes to skin inflammation. As UVB mostly affects the epidermis, with just 10% getting into the dermis, the crosstalk between…

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