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Abstracts tagged "urate lowering and urinary excretion"

  • Abstract Number: 1229 • ACR/ARP Annual Meeting 2019

    AR882, a Potent and Selective Uric Acid Lowering Agent Acting Through Inhibition of Uric Acid Reuptake, Shows Excellent Pharmacokinetics and Pharmacodynamics in a Phase 1 Clinical Trial

    zancong shen 1, Elizabeth Polvent 2, Vijay Hingorani 3, Shunqi Yan 4, Rongzi Yan 4 and Litain Yeh4, 1Arthrosi Therapeutics, San Diego, CA, 2Arthrosi Therapeutics, Laguna Hills, CA, 3Arthrosi Therapeutics, San Diego, 4Arthrosi Therapeutics, Laguna Hills

    Background/Purpose: AR882 is a potent and selective uric acid transporter 1 (URAT1) inhibitor under development for the treatment of hyperuricemia or gout. A Phase 1…
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