ACR Meeting Abstracts

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Abstracts tagged "URAT1"

  • Abstract Number: 1224 • 2019 ACR/ARP Annual Meeting

    AR882, a Potent and Selective URAT1 Inhibitor with a Favorable Pharmacological, Pharmacokinetic and Toxicity Profile

    Rongzi Yan1, Nanqun Zhu 2, zancong shen 3, Shunqi Yan 4 and Litain Yeh 1, 1Arthrosi Therapeutics, Laguna Hills, 2Consultant, Laguna Hills, CA, 3Arthrosi Therapeutics, San Diego, CA, 4Arthrosi Therapeutics. Inc, Laguna Hills, CA

    Background/Purpose: AR882 is a potent and selective inhibitor of uric acid transporter 1 (URAT1), which is responsible for a majority of reabsorption of filtered uric…
  • Abstract Number: 1229 • 2019 ACR/ARP Annual Meeting

    AR882, a Potent and Selective Uric Acid Lowering Agent Acting Through Inhibition of Uric Acid Reuptake, Shows Excellent Pharmacokinetics and Pharmacodynamics in a Phase 1 Clinical Trial

    zancong shen 1, Elizabeth Polvent 2, Vijay Hingorani 3, Shunqi Yan 4, Rongzi Yan 4 and Litain Yeh4, 1Arthrosi Therapeutics, San Diego, CA, 2Arthrosi Therapeutics, Laguna Hills, CA, 3Arthrosi Therapeutics, San Diego, 4Arthrosi Therapeutics, Laguna Hills

    Background/Purpose: AR882 is a potent and selective uric acid transporter 1 (URAT1) inhibitor under development for the treatment of hyperuricemia or gout. A Phase 1…
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