Abstracts tagged "URAT1"

Abstract Number: 1224 • 2019 ACR/ARP Annual Meeting
AR882, a Potent and Selective URAT1 Inhibitor with a Favorable Pharmacological, Pharmacokinetic and Toxicity Profile
Rongzi Yan¹, Nanqun Zhu ², zancong shen ³, Shunqi Yan ⁴ and Litain Yeh ¹, ¹Arthrosi Therapeutics, Laguna Hills, ²Consultant, Laguna Hills, CA, ³Arthrosi Therapeutics, San Diego, CA, ⁴Arthrosi Therapeutics. Inc, Laguna Hills, CA
Background/Purpose: AR882 is a potent and selective inhibitor of uric acid transporter 1 (URAT1), which is responsible for a majority of reabsorption of filtered uric…
Abstract Number: 1229 • 2019 ACR/ARP Annual Meeting
AR882, a Potent and Selective Uric Acid Lowering Agent Acting Through Inhibition of Uric Acid Reuptake, Shows Excellent Pharmacokinetics and Pharmacodynamics in a Phase 1 Clinical Trial
zancong shen ¹, Elizabeth Polvent ², Vijay Hingorani ³, Shunqi Yan ⁴, Rongzi Yan ⁴ and Litain Yeh⁴, ¹Arthrosi Therapeutics, San Diego, CA, ²Arthrosi Therapeutics, Laguna Hills, CA, ³Arthrosi Therapeutics, San Diego, ⁴Arthrosi Therapeutics, Laguna Hills
Background/Purpose: AR882 is a potent and selective uric acid transporter 1 (URAT1) inhibitor under development for the treatment of hyperuricemia or gout. A Phase 1…

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