Abstracts tagged "tuberculosis and tumor necrosis factor (TNF)"

Abstract Number: 1225 • 2018 ACR/ARHP Annual Meeting
Screening for Acquired Latent Tuberculosis in Patients with Rheumatoid Arthritis(RA) on Anti-Tnfα Therapy (TNF-I) in Southern California
Noopur Goel¹, Karina Torralba², Lorena Salto¹ and Christina Downey³, ¹Loma Linda University, Loma Linda, CA, ²Division of Rheumatology, Department of Internal Medicine, Loma Linda University, Loma Linda, CA, ³Loma Linda University Medical Center, Loma Linda, CA
Background/Purpose: There is increased risk of tuberculosis in patients treated with TNF-I. ACR guidelines recommend annual screening for latent tuberculosis infection(LTBI) in RA patients with…
Abstract Number: 1234 • 2018 ACR/ARHP Annual Meeting
Incidence of Conversion of Screening Tests for M. Tuberculosis (PPD, GIF-release assay) in a Metropolitan Cohort of Patients Treated with TNF-α Inhibitors
Hung Trinh and Darren Tabechian, Medicine, Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY
Background/Purpose: Tumor necrosis factor alpha (TNF-α) inhibitors are used to reduce the inflammatory process in many autoimmune diseases. Due to the risk of reactivation of…
Abstract Number: 1252 • 2018 ACR/ARHP Annual Meeting
Screening for Tuberculosis before Initiating TNF Inhibitors: How Well Do We Do? a Nationwide Experience
Karim Ladak¹, Ting Pan² and Catherine MacLean¹, ¹Rheumatology, Hospital For Special Surgery, New York, NY, ²Value Office, Hospital For Special Surgery, New York, NY
Background/Purpose: Tumor necrosis factor inhibitors (TNFi) revolutionized treatment of various conditions, however they drastically increase the risk of latent tuberculosis (LTBI) reactivation. Many national medical…
Abstract Number: 2598 • 2016 ACR/ARHP Annual Meeting
Conversion Rate of Tuberculosis Screening Tests in Patients with Rheumatic Diseases While Receiving Anti-Tumor Necrosis Factor Alpha (anti-TNFα) Agents
Syed Hasan Raza¹, Syed Islam², Amado Freire³, Debendra Pattanaik⁴ and John Stuart⁵, ¹Rheumatology, University of Tennessee Health Science Center, Memphis, TN, ²University of Tennessee Health Science Center, Memphis, TN, ³Pulmonology - Critical Care, University of Tennessee Health Science Center, Memphis, TN, ⁴Rheumatology, University of TN Health Science Center, Memphis, TN, ⁵Medicine, VA Medical Center, University of Tennessee Health Science Center, Memphis, TN
Background/Purpose: Risk of opportunistic infections, particularly mycobacterial infections, is increased among patients with rheumatic diseases treated with anti-TNF α agents. Therefore, screening of patients for…
Abstract Number: 1352 • 2015 ACR/ARHP Annual Meeting
How Frequently Does Tuberculosis Screening Test Become Positive in Rheumatic Patients Treated with ANTI-Tumor Necrosis Factor-ALPHA Therapy? an Analysis of Risk Factors
Jorge Gaspar Ramos¹, Dafhne Miranda², Pilar Cruz-Dominguez³, Luis Javier Jara⁴ and Miguel A. Saavedra⁵, ¹Rheumatology, Hospital de Especialidades, Dr. Antonio Fraga Mouret, Centro Medico Nacional La Raza, IMSS, Mexico City, Mexico, ²Rheumatology, Rheumatology Unit, Hospital de Especialidades. Centro Médico La Raza, IMSS, Distrito federal, Mexico, ³Centro Médico Nacional La Raza IMSS, México, Mexico, ⁴Instituto Mexicano del Seguro Social, Mexico City, Mexico, ⁵Reumatología, Centro Médico Nacional La Raza IMSS, México DF., México D.F., Mexico
Background/Purpose: Anti-tumor necrosis factor-α (TNF-α) therapy is associated with an increased risk of mycobacterium tuberculosis infection. Tuberculosis (TB) reactivation can lead to severe complications in…
Abstract Number: 2810 • 2013 ACR/ARHP Annual Meeting
Follow-Up Testing Of Interferon-Gamma Release Assays For The Diagnosis Of Hidden Tuberculosis Infection In Patients Receiving Tumor Necrosis Factor Alpha Antagonists
Chan-Nam Son¹, Tae-Hwan Kim², Il-Hoon Sung³, Jae-Bum Jun² and Dae-Hyun Yoo², ¹Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, South Korea, ²Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ³Orthopaedic surgery, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea
Background/Purpose: Anti-tumor necrosis factor alpha (Anti-TNFα) therapy is often used in patients with rheumatic diseases who do not respond to conventional treatment. Risk of tuberculosis…
Abstract Number: 1521 • 2013 ACR/ARHP Annual Meeting
Latent Tuberculosis Screening and Treatment In Ankylosing Spondylitis Patients Eligible For Anti-TNF Therapy In Endemic Area
Renata Miossi¹, Karina Rossi Bonfiglioli¹, Carla G.S. Saad², Ana Cristina Ribeiro¹, Julio C. B. Moraes² and Eloisa Bonfá¹, ¹Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Reumatologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Anti-TNF agents have emerged as an important treatment for rheumatic diseases, particularly for ankylosing spondylitis (AS). Screening and treatment of latent tuberculosis infection (LTBI)…
Abstract Number: 1371 • 2013 ACR/ARHP Annual Meeting
Tuberculosis Infection In Patients With Tumor Necrosis Factor–α Antagonists In South Korea;retrospective Analysis Using By National Health Insurance Review and Assessment Service
Jong Wook Beom¹, Eun-Jung Park², Jinseok Kim³, Se Chang Park⁴ and Gi Hyeon Seo⁵, ¹Medicine, Jeju National University Hospital, Jeju, South Korea, ²Internal Medicine, Department of Medicine, Jeju National University Hospital, Jeju University School of Medicine, Republic of Korea, Jeju, South Korea, ³Internal Medicine, Jeju National University Hospital, Jeju, South Korea, ⁴Veterinary Medicine, Seoul National University, Seoul, South Korea, ⁵Health Insurance Review and Assessment Service, Seoul, South Korea
Background/Purpose: Tumor necrosis factor-α (TNF-α) antagonists bring new hope for treating rheumatoid arthritis (RA) over the past decade. However, the subsequent increased risk of developing…
Abstract Number: 1372 • 2013 ACR/ARHP Annual Meeting
Do We Really Identify Latent Tuberculosis? Comparison Of The Performance Of Tuberculin Skin Test and Interferon Gamma Release Assay Before Biologics: A Systematic Review and Meta-Analysis
Marie Locci¹, Françoise Barchechath-Flaisler², Jean-Louis Leroux¹ and Cécile Gaujoux-Viala³, ¹Nîmes University Hospital, Rheumatology Department, Nîmes, France, ²Nîmes University Hospital, Rheumatology Department, Nimes, France, ³EA 2415, Montpellier I University, Nîmes University Hospital, Rheumatology Department, Nîmes, France
Background/Purpose: Current guidelines mandate screening for latent tuberculosis infection prior to commencing anti-tumor necrosis factor therapy. However, many patients are already taking immunosuppressive therapy, which…

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