Abstracts tagged "treatment"

Abstract Number: 1316 • 2012 ACR/ARHP Annual Meeting
Long-Term Safety and Efficacy of 4-Weekly Certolizumab Pegol Combination and Monotherapy in Rheumatoid Arthritis: 5 Year Results from an Open Label Extension Study
Roy Fleischmann¹, Ronald F. van Vollenhoven², Jiri Vencovsky³, Rieke Alten⁴, Owen Davies⁵, Christian Stach⁶, Marc de Longueville⁷, Brenda Van Lunen⁸ and Ernest Choy⁹, ¹University of Texas Southwestern Medical Center at Dallas, Dallas, TX, ²Karolinska Institute, Stockholm, Sweden, ³Institute of Rheumatology, Prague, Czech Republic, ⁴Teaching Hospital of the Charité, University of Berlin, Berlin, Germany, ⁵UCB Pharma, Slough, United Kingdom, ⁶UCB Pharma, Monheim, Germany, ⁷Global Medical Affairs, UCB Pharma, Brussels, Belgium, ⁸UCB Pharma, Raleigh, NC, ⁹Section of Rheumatology, Cardiff University School of Medicine, Cardiff, United Kingdom
Background/Purpose: Certolizumab pegol (CZP) has been shown to be efficacious and have an acceptable safety profile when administered every 4 weeks (Q4W) as monotherapy (FAST4WARD,…
Abstract Number: 996 • 2012 ACR/ARHP Annual Meeting
Genetic Predictors of Methotrexate Efficacy and Toxicity in Early Rheumatoid Arthritis: Results From the Treatment of Early Aggressive Rheumatoid Arthritis Trial
Stella Aslibekyan¹, Elizabeth Brown², Richard J. Reynolds³, David T. Redden⁴, Sarah L. Morgan⁵, Joseph Baggott¹, Jin Sha¹, Larry W. Moreland⁶, James R. O'Dell⁷, Jeffrey R. Curtis⁸, S. Louis Bridges Jr.⁹ and Donna K. Arnett¹, ¹University of Alabama at Birmingham, Birmingham, AL, ²Univ of Alabama at Birmingham, Birmingham, AL, Birmingham, AL, ³Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁴Biostatistics, University of Alabama at Birmingham, Birmingham, AL, ⁵University of Alabama Birmingham, Birmingham, AL, ⁶Division of Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ⁷Dept of Internal Medicine, Univ of Nebraska Med Ctr, Omaha, NE, ⁸Rheumatology & Immunology, Univ of Alabama-Birmingham, Birmingham, AL, ⁹Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Methotrexate (MTX) has emerged as first-line therapy for early moderate to severe rheumatoid arthritis (RA), but individual variation in treatment efficacy and toxicity remains…
Abstract Number: 373 • 2012 ACR/ARHP Annual Meeting
Patient-Reported Outcomes in Early Rheumatoid Arthritis Patients Failing to Achieve Stable Low Disease Activity: Comparing Addition of Adalimumab to Methotrexate Monotherapy with Maintenance On Adalimumab Plus Methotrexate
Arthur Kavanaugh¹, Ronald F. van Vollenhoven², Paul Emery³, James W. Shaw⁴, Mary A. Cifaldi⁵, Stefan Florentinus⁶ and Josef S. Smolen⁷, ¹UCSD School of Medicine, La Jolla, CA, ²Karolinska Institute, Stockholm, Sweden, ³Division of Rheumatic and Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom, ⁴Global Health Economics and Outcomes Research, Abbott Laboratories, Abbott Park, IL, ⁵Abbott Laboratories, Abbott Park, IL, ⁶AbbVie, Rungis, France, ⁷Division of Rheumatology, Department of Internal Medicine III,, Medical University of Vienna and Hietzing Hospital, Vienna, Austria
Background/Purpose: Treat-to-target guidelines for rheumatoid arthritis (RA) suggest adjusting therapy every 3-6 months for pts who fail to achieve a disease activity target. However, pts…

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