ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstracts tagged "treatment"

  • Abstract Number: 948 • 2014 ACR/ARHP Annual Meeting

    A Phase 2b, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Dose-Finding, Multi-Center Study to Evaluate the Safety and Efficacy of ASP015K in Moderate to Severe Rheumatoid Arthritis Subjects Who Have Had an Inadequate Response to Methotrexate

    Alan J. Kivitz1, Anna Zubrzycka-Sienkiewicz2, Sergio R. Gutierrez-Ureña3, Jeffrey Poiley4, Rita Kristy5, Kathyjo Shay5 and Jay P. Garg5, 1Altoona Center for Clinical Research, Duncansville, PA, 2ARS Rheumatica sp. Zo.o, Reumatika, Warszawa, Poland, 3Hospital Civil de Guadalajara FAA, CUCS UdG, Guadalajara, Mexico, 4Arthritis Associates, Orlando, FL, 5Astellas Pharma Global Development, Northbrook, IL

    Background/Purpose ASP015K is a novel oral Janus kinase (JAK) inhibitor in development for the treatment of rheumatoid arthritis (RA). ASP015K inhibits JAK 1/3 with relative…
  • Abstract Number: 2487 • 2014 ACR/ARHP Annual Meeting

    Effects of Tofacitinib on Health Care Resource Utilization and Work Productivity in US Patients with Rheumatoid Arthritis

    V. Strand1, R. Riese2, R. Gerber2, D. Gruben2, A.G. Bushmakin2, E.Y. Mahgoub3 and G. Wallenstein2, 1Biopharmaceutical Consultant, Portola Valley, CA, 2Pfizer Inc, Groton, CT, 3Pfizer Inc, Collegeville, PA

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Here we describe health care resource utilization (HCRU) and work…
  • Abstract Number: 849 • 2014 ACR/ARHP Annual Meeting

    Tofacitinib, an Oral Janus Kinase Inhibitor, in the Treatment of Rheumatoid Arthritis: Safety and Efficacy in Open-Label, Long-Term Extension up to 6 Years

    J. Wollenhaupt1, J. Silverfield2, E.B. Lee3, S.P. Wood4, K. Terry4, H. Nakamura5, K. Kwok6, A. Anisfeld6, C. Nduaka4, R. Riese4 and L. Wang4, 1Schoen-Klinik Hamburg-Eilbek Teaching Hospital of the University of Hamburg, Hamburg, Germany, 2Healthpoint Medical Group, Tampa, FL, 3Seoul National University, Seoul, South Korea, 4Pfizer Inc, Groton, CT, 5Pfizer Inc, Tokyo, Japan, 6Pfizer Inc, New York, NY

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Here we report tofacitinib safety, tolerability, and durability of response…
  • Abstract Number: 2470 • 2014 ACR/ARHP Annual Meeting

    Treatment Strategy for Maximizating the Effect of Adalimumab in Japanese Patients with Rheumatoid Arthritis : Retrospective Analyses of Data Collected from the Patient Treated with Adalimumab in Routine Clinical Practice in Hamamatsu Area

    Toshiaki Miyamoto, Rheumatology, SEIREI HAMAMATSU GENERAL HOSPITAL, Hamamatsu, Japan

    Background/Purpose: Adalimumab (ADA) showed highly efficacious in rheumatoid arthritis (RA) in the clinical trials, although there is little evidence in daily clinical practice.The clinical usefulness…
  • Abstract Number: 508 • 2014 ACR/ARHP Annual Meeting

    Relationship Between NK Cell Count and Important Safety Events in Rheumatoid Arthritis Patients Treated with Tofacitinib

    R. van Vollenhoven1, Y. Tanaka2, R. Riese3, M. Lamba3, T. Kawabata3, T. Hirose4, S. Toyoizumi4, A. Hazra3 and S. Krishnaswami3, 1The Karolinska Institute, Stockholm, Sweden, 2University of Occupational and Environmental Health, Kitakyushu, Japan, 3Pfizer Inc, Groton, CT, 4Pfizer Inc, Tokyo, Japan

    Background/Purpose: Tofacitinib is an oral Janus kinase (JAK) inhibitor for the treatment of rheumatoid arthritis (RA). Cytokines (e.g. interleukin [IL]-2, -4, -7, -15, -21) involved…
  • Abstract Number: 2427 • 2014 ACR/ARHP Annual Meeting

    Attainment of Low Disease Activity Is Predictive of Maintenance of Disease Control upon Adalimumab Discontinuation for Two Years Following Combination Therapy in Japanese Patients with Early Rheumatoid Arthritis

    Yoshiya Tanaka1, Hisashi Yamanaka2, Naoki Ishiguro3, Nobuyuki Miyasaka4, Katsuyoshi Kawana5, Katsutoshi Hiramatsu6, Aki Kuroki5 and Tsutomu Takeuchi7, 1University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 2Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan, 3Orthopaedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan, 4Tokyo Medical and Dental University, Tokyo, Japan, 5Abbvie, Tokyo, Japan, 6Medical, Abbvie, Tokyo, Japan, 7Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan

    Background/Purpose: Although available data has suggested successful withdrawal of a monoclonal antibody TNF blocker after achieving low disease activity (LDA) or remission over the short-term…
  • Abstract Number: 511 • 2014 ACR/ARHP Annual Meeting

    First and Second Line Continuation Rates of Non Anti-TNF-α Biological DMARD for the Treatment of Rheumatoid Arthritis

    Tristan Pascart1, Rene-Marc Flipo2, Xavier Deprez3 and Eric Houvenagel4, 1Rheumatology, Saint-Philibert Hospital, Lille, France, 2Rheumatology, University Hospital Lille, Lille, France, 3Rhumatologie, Ch De Valenciennes, Valenciennes, France, 4Rheumatology, Saint-Philibert Hospital, LOMME, France

    Background/Purpose The 2013 update of the EULAR recommendations for the management of RA with synthetic and biological DMARDs set non-anti-TNF- α as first-line biological treatments.…
  • Abstract Number: 2428 • 2014 ACR/ARHP Annual Meeting

    Comparative Study of Rheumatoid Arthritis Disease Activity Indices in Two Populations of Meteor Database

    Helena Canhão1, Fernando Magalhaes Martins2, Jose Antonio Melo Gomes3, Maria Jose Santos4, Augusto Faustino5, José Antonio Costa6, Cornelia Allaart7, E. Gvozdenovic8, Pedro Machado9, Jaime C. Branco10, João E. Fonseca11 and José Pereira Da-Silva12, 1Av. Prof. Egas Moniz, Hospital Santa Maria, Lisboa, Portugal, 2Portuguese Society of Rheumatology, Lisbon, Portugal, 3Instituto Português de Reumatologia, Lisbon, Portugal, 4Rheumatology, Hospital Garcia de Orta, Almada, Portugal, 5Clínica de Reumatologia de Lisboa, Lisbon, Portugal, 6Rheumatology, Centro Hospitalar do Alto Minho, Hospital de Ponte de Lima, Ponte de Lima, Portugal, 7Rheumatology, Leiden Univ Med Ctr, Leiden, Netherlands, 8Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 9MRC Centre for Neuromuscular Diseases, University College London, London, United Kingdom, 10Rheumatology, Centro Hospitalar de Lisboa Ocidental, Hospital Egas Moniz, Lisboa, Portugal, 11Lisbon Academic Medical Center, Lisbon, Portugal, 12Rheumatology, Hospitais da Universidade de Coimbra, Coimbra, Portugal

    Background/Purpose Our aims were to assess disease activity states using DAS28ESR, CDAI and SDAI and to compare their outcomes in two rheumatoid arthritis (RA) populations…
  • Abstract Number: 497 • 2014 ACR/ARHP Annual Meeting

    Efficacy and Safety Study of a Sequential Therapy of Tocilizumab and, If Initially Inadequately Responded to Tocilizumab, Followed By Rituximab in Patients with Rheumatoid Arthritis and Inadequate Response to Traditional Disease Modifying Anti-Rheumatic Drugs

    Thomas Dörner1, Hans-Peter Tony2, Gerd Burmester1, Hendrik Schulze-Koops3, Jörg Kaufmann4, Peter Kästner5, Herbert Kellner6, Reiner Kurthen7, Sylke Wagner8, Marvin A. Peters9 and Christoph Iking-Konert10, 1Charité - Universitätsmedizin Berlin, Berlin, Germany, 2University Clinic Wuerzburg, Wuerzburg, Germany, 3University Clinic Munich, Munich, Germany, 4Rheumatology Practice, Ludwigsfelde, Germany, 5MVZ Out-patient Rheumatogy Unit Erfurt, Erfurt, Germany, 6Specialist Practice for Rheumatology and Gastroenterology, Munich, Germany, 7Rheumatology Practice, Aachen, Germany, 8Practice for Internal Medicine specialized in Rheumatology, Halle, Germany, 9Roche Pharma AG, Grenzach-Wyhlen, Germany, 10University Clinic Hamburg-Eppendorf, Hamburg, Germany

    Background/Purpose: The MIRAI study evaluated a sequential exposure to 2 defined biologics under rigorous study conditions within a homogeneous population of biological naïve patients (pts)…
  • Abstract Number: 2395 • 2014 ACR/ARHP Annual Meeting

    Understanding Patient Preferences Associated with the Use of Therapies for Rheumatoid Arthritis: Results of a Conjoint Analysis

    K. Saverno1, A. Louder1, A. Singh2, J. Cappelleri3, A. Aten4, A. Koenig5 and M. Pasquale1, 1Comprehensive Health Insights Inc, Louisville, KY, 2Pfizer Inc, Groton, CT, 3Pfizer Inc, New York, NY, 4Humana Inc, Louisville, KY, 5Pfizer Inc, Collegeville, PA

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Tofacitinib provides patients with a new oral alternative to biologic…
  • Abstract Number: 378 • 2014 ACR/ARHP Annual Meeting

    The Use of Week 12 CDAI, RAPID3 and DAS28(CRP) Responses to Predict Optimal Response to Methotrexate

    Gerd Burmester1, Gurjit S. Kaeley2, Jeffrey R. Curtis3, Yusuf Yazici4, Benoit Guerette5, Xin Wang5, Alan Friedman5 and Vibeke Strand6, 1Department of Rheumatology and Clinical Immunology, Charité University Medicine, Berlin, Germany, 2College of Medicine, University of Florida, Jacksonville, FL, 3University of Alabama at Birmingham, Birmingham, AL, 4Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 5AbbVie, Inc., North Chicago, IL, 6Adjunct, Division of Immunology / Rheumatology, Stanford University, Palo Alto, CA

    Background/Purpose The prediction of treatment outcomes based on early response could guide treatment decisions in patients (pts) with rheumatoid arthritis (RA). The objective was to…
  • Abstract Number: 2406 • 2014 ACR/ARHP Annual Meeting

    Primary Non-Adherence, Associated Clinical Outcomes and Healthcare Resource Utilization Among Rheumatoid Arthritis Patients Prescribed Injectable Biologics

    J. Harnett1, D. Wiederkehr1, R. Gerber2, D. Gruben2, J. Bourret3 and A. Koenig3, 1Pfizer Inc, New York, NY, 2Pfizer Inc, Groton, CT, 3Pfizer Inc, Collegeville, PA

    Background/Purpose: Injectable biologics are commonly used to treat patients (pts) with moderate to severe rheumatoid arthritis (RA); the frequency with which they are prescribed but…
  • Abstract Number: 100 • 2014 ACR/ARHP Annual Meeting

    Evaluation of Real World Experience with Non-Biologic DMARD in the Treatment of RA: Data from an Electronic Health Record Database

    D. Wiederkehr1, J. Harnett1, R. Gerber2, D. Gruben2, E.Y. Mahgoub3, G. Wallenstein1 and A. Koenig3, 1Pfizer Inc, New York, NY, 2Pfizer Inc, Groton, CT, 3Pfizer Inc, Collegeville, PA

    Background/Purpose: Non-biologic (NB) disease-modifying antirheumatic drugs (DMARD) such as methotrexate (MTX) are commonly used to treat rheumatoid arthritis (RA). However, NB‑DMARD can have adverse events…
  • Abstract Number: 2334 • 2013 ACR/ARHP Annual Meeting

    ORAL SCAN: Effects Of The Oral JAK Inhibitor Tofacitinib In Combination With Methotrexate On Patient Reported Outcomes In a 24-Month Phase 3 Trial Of Active Rheumatoid Arthritis

    V. Strand1, D. van der Heijde2, C. a. F. Zerbini3, C. A. Connell4, D. Gruben4, R. Riese4 and G. Wallenstein4, 1Adjunct, Division of Immunology / Rheumatology, Stanford University, Palo Alto, CA, 2Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Rheumatology, Centro Paulista de Investigação Clinica, Sao Paulo, Brazil, 4Pfizer Inc, Groton, CT

    Background/Purpose: Tofacitinib is an oral Janus kinase (JAK) inhibitor for the treatment of rheumatoid arthritis (RA). Efficacy, inhibition of structural damage, and safety of tofacitinib…
  • Abstract Number: 1391 • 2013 ACR/ARHP Annual Meeting

    Transporters As Drug Gateway Into The Cell For Specific Targeting Of Tyrosine Kinase Signaling Pathway In Rheumatoid Arthritis

    Saliha Harrach1, Christian Schmidt-Lauber2, Bayram Edemir3, Eberhard Schlatter1, Thomas Pap4, Giuliano Ciarimboli1 and Jessica Bertrand2, 1Experimental Nephrology, Medical Clinic und Policlinic D, University Hospital Münster, Münster, Germany, 2Institute of Experimental Musculoskeletal Medicine (IEMM), University Hospital Münster, Münster, Germany, 3Experimental Nephrology, Medical Clinic und Policlinic D, University Hospital Münster, Muenster, Germany, 4Institute of Experimental Muskuloskeletal Medicine, University Hospital Münster, Münster, Germany

    Background/Purpose: Tyrosine kinase inhibitors (TKI) are effective in treating malignant disorders and were suggested to also have an impact on non-malignant diseases such as rheumatoid…
  • « Previous Page
  • 1
  • …
  • 12
  • 13
  • 14
  • 15
  • 16
  • …
  • 22
  • Next Page »
Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

ACR Abstract Embargo Policy

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying financial and other sponsors about this policy. If you have questions about the abstract embargo policy, please contact the public relations department at [email protected].

Copyright Policy

View ACR Policies.

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology