Abstracts tagged "treatment and Janus kinase (JAK)"

Abstract Number: 547 • 2019 ACR/ARP Annual Meeting
Inhibition of Structural Joint Damage with Upadacitinib as Monotherapy or in Combination with Methotrexate in Patients with Rheumatoid Arthritis
Charles Peterfy¹, Mark Genovese ², In-Ho Song ³, Alan Friedman ⁴, Stephen Hall ⁵, Eduardo Mysler ⁶, Patrick Durez ⁷, Xenofon Baraliakos ⁸, Jose Jeffrey Enejosa ⁹, Tim Shaw ⁴, Yihan Li ⁹, Su Chen ⁴ and Vibeke Strand ¹⁰, ¹Spire Sciences Inc, Boca Raton, ²Stanford University, Stanford, CA, ³AbbVie Inc., North Chicago, IL, USA, North Chicago, IL, ⁴AbbVie Inc., North Chicago, ⁵Monash University and Emeritus Research, Melbourne, Australia, ⁶Organización Medica de Investigación, Buenos Aires, Argentina, Buenos Aires, Argentina, ⁷Pôle de Recherche en Rhumatologie, Institut de Recherche Expérimentale et Clinique, UCL Saint-Luc, Brussels, Belgium, ⁸Rheumatology Department, Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany, ⁹AbbVie Inc., North Chicago, IL, ¹⁰Division of Immunology/Rheumatology, Stanford University, Stanford, CA
Background/Purpose: Long‑term prevention of structural joint damage is a key treatment goal in the management of RA1. Upadacitinib (UPA), a JAK1-selective inhibitor, inhibited the progression…

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