Abstracts tagged "tocilizumab and treatment options"

Abstract Number: 1635 • 2015 ACR/ARHP Annual Meeting
Development of New Bioassay System Measuring Inhibitory Strength of IL-6/STAT3 Signal Under Tocilizumab Treatment in Rheumatoid Arthritis Patients
Shuntaro Saito¹, Katsuya Suzuki¹, Kunihiro Yamaoka¹ and Tsutomu Takeuchi², ¹Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ²Keio University School of Medicine, Tokyo, Japan
Background/Purpose: Tocilizumab (TCZ) is a IL-6 receptor blockade, administered intravenously every 4 weeks and efficiently inhibits IL-6/STAT3 signaling pathway. We have previously reported the usefulness…
Abstract Number: 2750 • 2015 ACR/ARHP Annual Meeting
Tocilizumab Is Effective As 1st, 2nd and 3rd-Line Biologic DMARD in Patients with Rheumatoid Arthritis
Adrian Richter¹, Anja Strangfeld², Joern Kekow³, Arnold Bussmann⁴, Andreas Krause⁵, Carsten Stille⁶, Joachim Listing⁷ and Angela Zink⁸, ¹German Rheumatism Research Center, Berlin, Germany, ²Epidemiology, German Rheumatism Research Center, Berlin, Germany, ³University of Magdeburg, Magdeburg, Germany, ⁴Rheumatologist, Geilenkirchen, Germany, ⁵Rheumatologist, Berlin, Germany, ⁶Rheumatologist, Hannover, Germany, ⁷Epidemiology, DRFZ, Berlin, Germany, ⁸Epidemiologie, Deutsches Rheuma-Forschungszentrum, Berlin, Germany
Background/Purpose: In Germany, treatment with Tocilizumab (TCZ) is primarily used in rheumatoid arthritis patients with previous failures of biologic DMARDs. Effectiveness and adherence of TCZ…

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