ACR Meeting Abstracts
Abstract Number: 1906 • ACR Convergence 2021
Danny Flores Castro1, Zhu Chen2, Sanjay Gupta3, Michela Manni3, Juan Rivera Correa3, Max Chao4, Yurii Chinenov4, Tania Pannellini5, Habib Zaghouni6, Rolf Jessberger7 and Alessandra Pernis8, 1Autoimmunity and Inflammation Program, Hospital for Special Surgery, Palisades Park, NJ, 2Department of Rheumatology and Immunology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China (People's Republic), 3Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, NY, 4David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY, 5Research Division and Precision Medicine Laboratory, Hospital for Special Surgery, New York, NY, 6Department of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, MO, 7Institute of Physiological Chemistry, Technische Universitat, Dresden, Germany, 8Department of Medicine, Weill Cornell Medicine, New York, NY
Background/Purpose: Age-associated B cells (ABCs) are an emerging B cell subset that aberrantly expand in SLE. ABC generation and differentiation exhibit marked sexual dimorphism and…