Abstracts tagged "tissue remodeling and tumor necrosis factor (TNF)"

Abstract Number: 462 • 2016 ACR/ARHP Annual Meeting
Selective Inhibition of MMP9 Using a Monoclonal Antibody As a Therapeutic Strategy for Rheumatoid Arthritis
Sunhwa Kim¹, Brian Carr¹, Leah Tong¹, Debi Jin¹, Ruth Wang¹, Derrek Marshall¹, David Gossage² and Victoria Smith¹, ¹Biology, Gilead Sciences, Inc., Foster city, CA, ²Biology, Gilead Sciences, Inc., foster city, CA
Background/Purpose: Matrix metalloproteinase-9 (MMP9), highly expressed by infiltrating inflammatory cells, pannus tissue, and multinucleated cells in the synovium and subchondral bone tissue, including osteoclasts, participates…

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Abstracts tagged "tissue remodeling and tumor necrosis factor (TNF)"

Selective Inhibition of MMP9 Using a Monoclonal Antibody As a Therapeutic Strategy for Rheumatoid Arthritis