Abstracts tagged "Therapy, complementary"

Abstract Number: 2028 • ACR Convergence 2024
Therapeutic Insights in VEXAS Syndrome from a Multicenter Study in Spain: Moving Towards Amore Specific and Effective Treatment
Marta López I Gómez¹, Paula García Escudero², Berta Magallanes López³, Alicia García Dorta⁴, Beatriz Frade-Sosa⁵, Meritxell Sallés Lizarzaburu⁶, Íñigo Rúa-Figueroa⁷, Dolly Viviana Fiallo Suárez⁸, Francisco Javier Toyos Sáenz de Miera⁹, Rafael Benito Melero-Gonzalez¹⁰, Diego Dios Santos¹¹, Jose Alberto Miranda¹², Clara Garcia Belando¹³, Giuliano Boselli¹⁴, Alina Lucica Boteanu¹⁵, Cristina Corrales Selaya¹⁶, cristiana sieiro santos¹⁷, Elvira Díez Álvarez¹⁸, Judit Font¹⁹, Elena Riera Alonso²⁰, Ernesto Trallero Araguás²¹, Eugenia Enríquez Merayo²², Maria Rodriguez-Laguna²³, irene monjo²⁴, Ignacio Vázquez Gómez²⁵, Paloma Vela-Casasempere²⁶, Carolina Merino²⁷, Marta Ibáñez Martínez²⁸, José Ángel Hernández Beriain²⁹, ALBERTO MARIANO RUIZ ROMAN³⁰ and Jaime Calvo-Alén³¹, ¹Hospital Universitario Alava, Vitoria, Pais Vasco, Spain, ²Hospital Universitario Araba, Vitoria, ³Hospital de la Santa Creu i Sant Pau, Barcelona, ⁴Rheumatologist, La Laguna, Spain, ⁵Hospital Clinic de Barcelona, Barcelona, Spain, ⁶Althaia Xarxa Assistencial Universitària Manresa, Manresa, Catalonia, Spain, ⁷Department of Rheumatology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Las Palmas GC, Spain, ⁸H. U. de Gran Canaria. Dr. Negrin, H. U. de Gran Canaria, ⁹H. U. Virgen Macarena, H. U. Virgen Macarena, ¹⁰CHU Ourense, O Carballino, Spain, ¹¹C. H. U. A Coruña, C. H. U. A Coruña, ¹²C. H. U. Lucus Augusti (Lugo), (Lugo), ¹³H. C. U. Virgen de la Arrixaca, Murcia, ¹⁴hospital miguel servet, zaragoza, Aragon, Spain, ¹⁵H.U. Ramón y Cajal, Madrid, Spain, ¹⁶Rheumatology, Marques de Valdecilla University Hospital. IDIVAL, Santander, Cantabria, Spain, ¹⁷Rheumatology Department, Complejo Asistencial Universitario de León, León, Spain, Leon, Spain, ¹⁸Complejo Asistencial Universitario de León, León, Spain, ¹⁹Hospital Germans Trias i Pujol, Barcelona, Spain, ²⁰Mutua de Terrasa, Barcelona, ²¹Hospital Vall D'Hebron, Barcelona, Spain, ²²Hospital 12 de Octubre, Madrid, ²³Resident in Rheumatology, Madrid, Spain, ²⁴University Hospital La Paz, Madrid, Spain, ²⁵H. U. Dr. Peset, Valencia, ²⁶Hospital General Universitario Alicante, Alicante, Spain, ²⁷Hospital Universitario Puerta de Hierro Majadahonda., Majadahonda (Madrid), Spain, ²⁸Hospital Clínico Universitario de Salamanca, Salamanca, Spain, ²⁹Rheumatology Department. Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran C, Spain, ³⁰Hospital Universitario Juan Ramón Jiménez, Huelva, Spain, ³¹Department of Rheumatology, Hospital Araba, Vitoria, Pais Vasco, Spain
Background/Purpose: Nearly four years since its characterization, management and therapeutic algorithms for VEXAS syndrome remain unclear. This study aims to describe treatment approaches and assess…
Abstract Number: 2092 • ACR Convergence 2024
Remote-Delivered Tai Chi and Gut Microbiota in Osteoarthritis: A Randomized Mechanistic Trial
Chenchen Wang¹, Timothy McAlindon², Meghan Short¹, Mei Chung³, Ye Chen¹, Albert Tai¹ and Honorine Ward¹, ¹Tufts Medical Center, Boston, MA, ²University of Massachusets, Worchester, MA, ³Tufts Medical Center, Brighton, MA
Background/Purpose: Previous studies show that Tai Chi achieves clinical improvement for osteoarthritis (OA) through multiple pathways. There is evidence for interaction of the gut microbiota…
Abstract Number: 2255 • ACR Convergence 2024
Differences in Pharmacological Prescription to Patients with Recent-onset Arthritis: Analysis from the Gender Perspective
Maryia Nikitsina, María Ahijón Lana and Isidoro González-Álvaro, University Hospital La Princesa, Madrid, Madrid, Spain
Background/Purpose: Nowadays the honing in on sex-specific treatment options is the most productive way to move forward with the larger effort of implementing precision medicine.…
Abstract Number: 0160 • ACR Convergence 2024
Supplement Use in a Diverse Cohort of Individuals with SLE
Russell Ellyson¹, Jinoos Yazdany², S. Sam Lim³, Brad Pearce³ and Laura Plantinga⁴, ¹Alameda Health System, Highland Hospital, Oakland, CA, ²UCSF, San Francisco, CA, ³Emory University, Atlanta, GA, ⁴University of California, San Francisco, San Francisco, CA
Background/Purpose: Supplement use among individuals with SLE is not well-characterized, despite potential effects of some supplements on SLE activity or on treatments for SLE or…
Abstract Number: 2456 • ACR Convergence 2024
High Levels of Circulating IFNα Are Associated with Increased Mortality in Patients with Diffuse Cutaneous Systemic Sclerosis
François Maillet¹, Carine Schmidt¹, Vincent Bondet², Alexandre Bense¹, Darragh Duffy³, Luc Mouthon¹, Mathieu Paul Rodero⁴ and Benjamin Chaigne⁵, ¹AP HP, Paris, France, ²INSERM PAsteur Institute, Paris, France, ³Inserm Pasteur Institue, Paris, France, ⁴Université Paris CIté, Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques, Faculté des Saint-Pères, Paris, France, ⁵Service de Médecine Interne, Centre de Référence Maladies Systémiques Autoimmunes et Autoinflammatoires Rares d'Ile de France de l’Est et de l’Ouest, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, Ile-de-France, France
Background/Purpose: Systemic sclerosis (SSc) is a connective tissue disease characterized by skin and organ fibrosis, autoimmunity, and vasculopathy. Although its pathophysiology remains unclear, recent data…
Abstract Number: 0341 • ACR Convergence 2024
Efficacy and Safety of Nintedanib in Patients with Idiopathic Inflammatory Myopathy-related Interstitial Lung Disease
Kaito Aoki¹, Keigo Shimura¹, Toshiki Ohisa¹, Akira Ishii¹, Mai Sugiyama², Yuichiro Ota¹, Ayumi Nishikawa³, Noriko Sasaki³, Chiho Yamada¹ and Shinji Sato², ¹Tokai University School of Medicine, Isehara, Japan, ²Tokai University, Isehara, Japan, ³Tokai University Hachioji Hospital, Hachioji, Japan
Background/Purpose: Idiopathic inflammatory myopathies (IIM) are chronic inflammatory disorders that affect muscle, skin and lung to varying degrees. Interstitial lung disease (ILD) is a major…
Abstract Number: 2535 • ACR Convergence 2024
The Lipidomic and Proteomic Profiles in Antiphospholipid Syndrome Patients Are Intricately Linked to Disease Pathogenesis and Modulated by Ubiquinol Supplementation
Chary Lopez-Pedrera¹, Beatriz Vellón-García², Mª Angeles Aguirre-Zamorano³, Sagrario Corrales⁴, Ismael Sánchez Pareja⁴, Laura Muñoz-Barrera⁴, Tomás Cerdó⁴, Pedro Segui⁵, Christian Merlo⁵, María del carmen ábalos-Aguilera⁵, Nuria Barbarroja⁴, Alejandro Escudero-Contreras⁶, Rafaela Ortega-Castro⁷, José Manuel Villalba⁸ and Carlos Perez-Sanchez⁴, ¹IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Andalucia, Spain, ²Department of Cell Biology, Immunology and Physiology, University of Cordoba (UCO), Agrifood Campus of International Excellence, (ceiA3) / Rheumatology Service, Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain, ³IMIBIC/Reina Sofia Hospital/University of Cordoba, CÓRDOBA, Andalucia, Spain, ⁴IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, ⁵Rheumatology Service, Maimonides Institute of Biomedical Research of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain, ⁶Reina Sofia University Hospital, Córdoba, Spain, ⁷Hospital Reina Sofía, Cordoba, Andalucia, Spain, ⁸Department of Cell Biology, Immunology and Physiology, University of Cordoba (UCO), Agrifood Campus of International Excellence, (ceiA3), Cordoba, Spain
Background/Purpose: This study aims to:1) Characterize the circulating lipidomic and proteomic profiles of APS patient and analyse its association with clinical features.2) Investigate the short-term…
Abstract Number: 0712 • ACR Convergence 2024
Efficacy of Sacubitril/Valsartan in Patients with Systemic Sclerosis and Heart Failure: A Retrospective Analysis
Nouran Eshak¹, Mahmoud Abdelnabi², Jaxon Quillen¹, Michael Pham¹, Joseph Hentz¹ and Vivek Nagaraja¹, ¹Mayo Clinic Arizona, Scottsdale, AZ, ²Mayo Clinic Arizona, Phoenix, AZ
Background/Purpose: Cardiac involvement in systemic sclerosis (SSc) is common, underdiagnosed, and manifests variably. Myocardial involvement can manifest as left heart failure with preserved or reduced…
Abstract Number: 2577 • ACR Convergence 2024
Efficacy and Safety of ABBV-599 (Elsubrutinib and Upadacitinib Combination) and Upadacitinib Monotherapy for the Treatment of Systemic Lupus Erythematosus: Results Through 104 Weeks in a Long-Term Extension Study
Joan Merrill¹, Amit Saxena², Martin Aringer³, Yoshiya Tanaka⁴, Xiaofeng Zeng⁵, Peter Wung⁶, Ling Cheng⁶, Thao Doan⁶, Shelly Kafka⁶, David DCruz⁷ and Kristin D'Silva⁶, ¹Oklahoma Medical Research Foundation, Oklahoma City 73104, OK, ²NYU Grossman School of Medicine, New York, NY, ³University Medical Center and Faculty of Medicine, TU Dresden, Dresden, Germany, ⁴Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan, ⁵Department of Rheumatology, Peking Union Medical College Hospital (PUMCH), Chinese Academy of Medical Sciences National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Beijing, China, ⁶AbbVie Inc., North Chicago, IL, ⁷The Louise Coote Lupus Unit, Guy's and St Thomas' Hospitals NHS Foundation Trust, London, United Kingdom
Background/Purpose: ABBV-599 (a combination of a selective Bruton’s tyrosine kinase inhibitor, elsubrutinib [ELS], and a selective Janus kinase inhibitor, upadacitinib [UPA]) targets a spectrum of…
Abstract Number: 1128 • ACR Convergence 2024
A Meta-Analysis of Statin Efficacy in Controlling Disease Activity in Psoriasis
Barbara Abreu Lopez¹, Ernesto Calderon Martinez², Tania Siu Xiao³, Zulma Sosa Carcamo⁴, Alejandra Maria Aleman Reyes⁵, Felix Ricardo Bonilla Bonilla⁶, María Isabel Murillo Pineda⁵, Edgar Josué Sanabria Herrera⁷, Alberto Ayala Aguilar⁸, Adreina Del Valle Rojas Marron⁹, Valentina Contreras Duran,¹⁰, Kevin J. Lopez Romero¹¹ and Marcela Garzon¹², ¹Universidad de Carabobo, Carabobo, Venezuela, ²The University of Texas Science Medical Center at Houston, Tomball, ³Thomas Jefferson University Hospital, Philadelphia, ⁴Universidad Evangélica de El Salvador, San Salvador, El Salvador, ⁵Universidad Católica de Honduras, Tegucigalpa, Honduras, ⁶Hospital Militar Central, San Salvador, El Salvador, ⁷Universidad Nacional Autónoma de Honduras, Tegucigalpa, ⁸Baylor College of Medicine, Houston, ⁹Universidad de Oriente Núcleo Anzoátegui, Barcelona, Venezuela, ¹⁰MD Anderson Cancer Center, Texas, Houston, ¹¹Universidad de El Salvador, San Salvador, El Salvador, ¹²Universidad de Los Andes, Bogotá, Colombia
Background/Purpose: Psoriasis is a chronic inflammatory skin disorder that is associated with an increased risk of cardiovascular diseases. Chronic inflammation in psoriasis can produce excessive…
Abstract Number: 1174 • ACR Convergence 2024
Effects of Electroacupuncture on Pain and Joint Deformity in Rat Models of Knee Osteoarthritis: A Study on the Differences in Acupoints Used
Hideshi Ikemoto, Oyunchimeg Chuluunbat, Takayuki Okumo, Naoki Adachi, Tadashi Hisamitsu and Masataka Sunagawa, Showa university, Shinagawa-ku, Tokyo, Japan
Background/Purpose: ADAMTS5, a member of the ADAMTS enzyme family, is a key enzyme in the degradation of cartilage in the early stages of knee osteoarthritis…
Abstract Number: 1178 • ACR Convergence 2024
Can Immersive Virtual Reality Improve the Effect of Meditation for People with Fibromyalgia?
Nancy Baker¹, Aliza Spielman¹ and Robert Edwards², ¹Tufts University, Medford, ²Brigham and Women's Hospital, Boston, MA
Background/Purpose: Fibromyalgia (FM) is a common and disabling condition characterized by widespread muscular pain. Meditation has been shown to alleviate affective pain in people with…
Abstract Number: 1217 • ACR Convergence 2024
Medical and Non-Medical Cannabis Use by Rheumatology Patients: A Study of over 2000 Patients in California
Maggie Hui¹, Nicholas Jackson², Angela Pham¹, Keren Chen², David Elashoff², ziva Cooper³ and Veena Ranganath⁴, ¹David Geffen School of Medicine at UCLA, Los Angeles, ²UCLA Department of Medicine Statistics Core, Los Angeles, ³UCLA Center for Cannabis and Cannabinoids, Semel Institute for Neuroscience & Human Behavior, Dept of Psychiatry and Biobehavioral Sciences, Dept of Anesthesiology and Perioperative Medicine, Los Angeles, ⁴UCLA, Los Angeles, CA
Background/Purpose: Approximately 12-20% of Rheumatology patients use cannabis (Fitzcharles 2020, Wipfler 2022, Rampakakis 2023). Despite the legalization of medical cannabis in California more than 2…
Abstract Number: 1415 • ACR Convergence 2024
Metformin Improves Salivary Gland Infiltration and Objective Measures of Dry Eyes in Sjögren’s Disease: A Retrospective Observational Study
Astrid Rasmussen¹, Alan Baer², Thomas Grader-Beck³, Margaret Beach⁴, Blake M. Warner⁵, Christopher Lessard¹, A. Darise Farris¹ and Robert Hal Scofield¹, ¹Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Johns Hopkins University School of Medicine, Baltimore, MD, ³Johns Hopkins, Baltimore, MD, ⁴NIH/NIDCR, Arlington, VA, ⁵National Institutes of Health, Bethesda, MD
Background/Purpose: Metformin (Met) is a widely used, first-line antidiabetic drug with AMPK-dependent anti-inflammatory and immunomodulatory effects. In in vitro studies and human trials in SLE…
Abstract Number: 1459 • ACR Convergence 2024
Dietary Modification and Intermittent Fasting Are Common in Patients with Axial Spondylarthritis and May Lead to Reduced Inflammatory Activity
Michael Nissen¹, Adrian Ciurea², Raphael Micheroli³, Eric Trunk⁴ and Delphine Courvoisier⁵, ¹Geneva University Hospital, Geneva, Switzerland, ²University Hospital Zurich, Zürich, Switzerland, ³University Hospital Zurich, Zurich, Switzerland, ⁴Geneva University Hospital, Geenva, Switzerland, ⁵University Hospitals of Geneva, Geneva, Switzerland
Background/Purpose: Current EULAR recommendations highlight the importance of a healthy, balanced diet in patients with inflammatory rheumatic disease, including axial spondylarthritis (axSpA). A Mediterranean-style diet…

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