Abstracts tagged "therapy and toll-like receptors"

Abstract Number: 2791 • 2016 ACR/ARHP Annual Meeting
Targeting Micro-RNAs Derived from Extracellular Vesicles to Inhibit of TLR7 and TLR8 Signaling Suppresses Inflammation in a Novel Human-Mouse Chimeric Model of Systemic Lupus Erythematosus
Nicholas A. Young¹, Giancarlo R. Valiente², Holly Steigelman³, Jeffrey Hampton⁴ and Wael N. Jarjour⁵, ¹Immunology and Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, ²Rheumatology & Immunology, The Ohio State University Wexner Medical Center, Columbus, OH, ³The Ohio State University, Columbus, OH, ⁴Immunology and Rheumatoloty, The Ohio State University Wexner Medical Center, Columbus, OH, ⁵Department of Rheumatology/Medicine, Ohio State University, Columbus, OH
Background/Purpose: Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease displaying a heavy female predominance during reproductive years. We have previously shown that toll-like receptor…

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Abstracts tagged "therapy and toll-like receptors"

Targeting Micro-RNAs Derived from Extracellular Vesicles to Inhibit of TLR7 and TLR8 Signaling Suppresses Inflammation in a Novel Human-Mouse Chimeric Model of Systemic Lupus Erythematosus