Abstracts tagged "Telomeres and rheumatoid arthritis (RA)"

Abstract Number: 1574 • 2016 ACR/ARHP Annual Meeting
The Role of Shelterin Deficiency in the Senescence in T Cells of Rheumatoid Arthritis
Wenjie Zheng¹, Lili Zhang², Hua Chen³ and Yan Zhao¹, ¹Rheumatology, Peking Union Medical College Hospital, Beijing, China, ²Infection and Immunity, Tianjin people's hospital, Tianjing, China, ³Peking Union Medical College Hospital, Beijing, China
Background/Purpose: T cells abnormality is an essential part in the pathogenesis of rheumatoid arthritis (RA), which includes a signature of premature immune aging, and restricted…
Abstract Number: 1606 • 2015 ACR/ARHP Annual Meeting
Telomere Damage in Rheumatoid Arthritis
Yinyin Li¹, Jihang Ju¹, Thomas M. Bush², Mark C. Genovese³, Jorg Goronzy¹ and Cornelia M. Weyand⁴, ¹Medicine: Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, ²Medicine/Rheumatology, Santa Clara Valley Medical Center, San Jose, CA, ³Division of Rheumatology, Stanford University Medical Center, Palo Alto, CA, ⁴Medicine, Stanford University School of Medicine, Stanford, CA
Background/Purpose: Production of anti-CCP autoantibodies, the hallmark of rheumatoid arthritis (RA), is dependent on T cell help, positioning T cells into a pinnacle position in…

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