ACR Meeting Abstracts

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Abstracts tagged "Takayasu.s arteritis"

  • Abstract Number: 1878 • ACR Convergence 2021

    Tocilizumab in Caucasian Patients with Takayasu Arteritis: Multicenter Study of 54 Patients

    Diana Prieto-Peña1, Pilar Bernabeu2, Paloma Vela3, Javier Narvaez4, Jesús Carlos Fernández-López5, Mercedes Freire6, Beatriz González-Alvarez7, Roser Solans-Laqué8, José Luis Callejas9, Norberto Ortego10, Carlos Fernández-Díaz11, Esteban Rubio Romero12, Salvador Garcia-Morillo13, Mauricio Minguez14, Cristina Carballido14, Eugenio De Miguel15, Sheila Melchor16, Eva Salgado17, Beatriz Bravo18, Susana Romero-Yuste19, Juan Salvatierra20, Cristina Hidalgo21, Sara Manrique Arija22, Carlos Romero Gomez23, Patricia Moya24, Noelia Álvarez-Rivas25, Javier Mendizábal-Mateos26, Francisco Ortiz-Sanjuán27, Ivan Perez De Pedro28, Jose L Alonso-Valdivielso29, Laura Perez-Sanchez30, Rosa Roldan31, Nagore Fernandez-Llanio32, Ricardo Gómez de la Torre33, Silvia Suarez33, Mara Jess Montesa Cabrera34, MONICA DELGADO SANCHEZ35, Javier Loricera1, Belén Atienza-Mateo36, Miguel Ángel gonzalez-Gay37 and Ricardo Blanco38, 1Hospital Universitario Marqués de Valdecilla, santander, Spain, 2Hospital General Universitario de Alicante-ISABIAL, Alicante, Spain, 3Hospital General Universitario de Alicante, Alicante, Spain, 4Division of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 5Hospital Universitario Juan Canalejo, A Coruña, Spain, 6Rheumatology Service. CHU Coruña, La Coruña, Spain, 7H. NªSª de la Candelaria, Tenerife, Spain, 8Hospital Vall d'Hebron, Barcelona, Spain, 9Hospital San Cecilio, Granada, Spain, 10Medicine Department, Universidad de Granada, Granada, Spain, 11Hospital Universitario Reina Sofía, Murcia, Spain, 12HOSPITAL UNIVERSITARIO VIRGEN DEL ROCIO, Seville, Spain, 13H Virgen del Rocio, Sevilla, Spain, 14H. San Juan, Alicante, Spain, 15Hospital Universitario La Paz, Madrid, Spain, 16H. 12 de Octubre, Madrid, Spain, 17Complejo Hospitalario Universitario de Ourense, Ourense, Spain, 18Hospital Universitario Virgen de las Nieves, Granada, Spain, 19Complejo Hospitalario Universitario de Pontevedra, Pontevedra, Spain, 20H San Juan, Alicante, Spain, 21Hospital Universitario Salamanca, Salamanca, Spain, 22Hospital Regional de Málaga, Málaga. Spain., Malaga, Spain, 23H. Regional de Malaga, Malaga, Spain, 24Hospital Sant Pau, Barcelona, Spain, 25Hospital San Agustín, Aviles, Spain, 26H. Navarra, Navarra, Spain, 27H. La Fe, Valencia, Spain, 28H. Carlos Haya, Malaga, Spain, 29H. Burgos, Burgos, Spain, 30IMIBIC/Reina Sofia Hospital/University of Córdoba, Córdoba, Spain, 31H. Reina Sofia, Cordoba, Spain, 32H. Arnau de Vilanova, Valencia, Spain, 33H. Asturias, Oviedo, Spain, 34Hospital Universitario Nuestra Seora de la Candelaria, Santa Cruz de Tenerife, Spain, 35H NªSª Candelaria, Tenerife, Spain, 36Group "Research in genetic epidemiology and atherosclerosis of systemic diseases and in bone metabolic diseases of the locomotor system", IDIVAL; and Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 37Research group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL, Division of Rheumatology, Hospital Universitario Marqués de Valdecilla; School of Medicine, Universidad de Cantabria, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 38Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Tocilizumab (TCZ) has shown to be effective for large vessel vasculitis including Takayasu arteritis (TAK) (1-3). Most evidence in TAK comes from Asian patients.…
  • Abstract Number: 1882 • ACR Convergence 2021

    Clinical Characteristics and Reliability of a Self-Reported Diagnosis of Large-Vessel Vasculitis

    Tannaz Kermani1, Jason Springer2, Dianne Shaw3, Kalen Young4, Cristina Burroughs5 and Peter Merkel6, 1University of California Los Angeles, Los Angeles, CA, 2Vanderbilt University Medical Center, Franklin, TN, 3Vasculitis Foundation, Chapel Hill, NC, 4Vasculitis Foundation, Kansas City, MO, 5Health Informatics Institute, Tampa, FL, 6University of Pennsylvania, Philadelphia, PA

    Background/Purpose: To compare the clinical characteristics and determine the reliability of a self-reported diagnosis of giant cell arteritis (GCA) or Takayasu’s arteritis (TAK) from an…
  • Abstract Number: 1886 • ACR Convergence 2021

    Validation of Angiographic Patterns of Disease in a Turkish Cohort of Patients with Takayasu’s Arteritis

    K. Bates Gribbons1, SEMA KAYMAZ-TAHRA2, Fatma Alibaz3, Ertugrul Cagri bolek4, Omer Karadag5, Burak Ince6, Murat Inanc7, Sinem Kocaer8, Fatos Onen9, KENAN AKSU10, Gokhan Keser11, Askin Ates12, Ayten Yazici13, Ayse Cefle13, Nilufer Alpay Kanitez14, Ahmet Omma15, Onay Gercik16, Servet Akar17, Veli Cobankara18, Nazife Sule Yasar Bilge19, Timucin Kasifoglu20, Mete Kara11, Kaitlin Quinn21, Peter Grayson22, Peter Merkel23 and Haner Direskeneli24, 1McGovern Medical School, Colleyville, TX, 2Marmara University Faculty of Medicine, Rheumatology, Istanbul, Turkey, 3Marmara University, School of Medicine, Rheumatology, Istanbul, Turkey, 4Vasculitis Translational Research Program, NIAMS, NIH, US, Lanham, MD, 5Hacettepe University, Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Ankara, Turkey, 6Istanbul Faculty of Medicine, Istanbul University, Division of Rheumatology, İstanbul, Turkey, 7Istanbul University Faculty of Medicine, Istanbul, Turkey, 8Dokuz Eylul University, Izmer, Turkey, 9Dokuz Eylul University, Izmir, Turkey, 10EGE UNIV. FACULTY of MEDICINE, IZMIR, Turkey, 11Ege University, İzmir, Turkey, 12Ankara University, Ankara, Turkey, 13Kocaeli University, Kocaeli, Turkey, 14Koc University School of Medicine, Istanbul, Turkey, 15Ankara City Hospital, Istanbul, Turkey, 16Izmir Katip Celebi University, Izmir, Turkey, 17Izmir Katip Celebi University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Izmir, Turkey, 18Pamukkale University, Denizli, Turkey, 19Eskisehir Osmangazi University Medical Faculty, Eskisehir, Turkey, 20Osmangazi University Department of Rheumatology, Eskişehir, Turkey, 21National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Washington, DC, 22National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, 23University of Pennsylvania, Philadelphia, PA, 24Marmara University, Istanbul, Turkey

    Background/Purpose: Previous studies using computer-driven methods have identified subsets of patients with Takayasu’s arteritis based on angiographic patterns of disease. These subsets were consistent between…
  • Abstract Number: 0151 • ACR Convergence 2021

    Usefulness of Ultrasound and (FDG) PET/CT to Detect Cranial and Extracranial Artery Involvement in Patients with Suspected Large Vessel Vasculitis

    Juan Molina1, Isabel Castrejón2, Javier Rivera2, Julia Martínez Barrio2, Juan Carlos Nieto2, Katerine López2, Fernando Montero2, Laura Trives Folguera2, Carlos González3 and Jose Maria Alvaro-Gracia2, 1Hospital General Universitario Gregorio Maran, Madrid, Spain, 2Hospital General Universitario Gregorio Marañón, Madrid, Spain, 3CEIMI, Hospital General Universitario Gregorio Marañón, Madrid, Spain

    Background/Purpose: Ultrasound (US) is recommended as the first imaging modality to assess patients presenting with predominantly cranial symptoms of giant cell arteritis (GCA). However, its…
  • Abstract Number: 0161 • ACR Convergence 2021

    Does 18F-FDG-PET/MRI Add Metabolic Information to Anatomic Image in Childhood-onset Takayasu’s Arteritis Patients? A Multicenter Case Series

    Gleice Clemente1, Alexandre Souza2, Hilton Leão Filho3, Fernando Coelho3, Carlos Buchpiguel4, Marcos Lima4, Daniela Petry Pioto5, Melissa Fraga1, Ana Paula Sakamoto6, Camila Carneiro4, Rosa Pereira7, Nadia Aikawa7, Clovis Artur Silva7, Lucia Campos8, Camilla Astley9, Bruno Gualano10 and Maria Terreri11, 1Universidade Federal de São Paulo, São Paulo, Brazil, 2UNIFESP-EPM, São Paulo, Brazil, 3Universidade de Sao Paulo/Radiology Institute, São Paulo, Brazil, 4Universidade de São Paulo/Department of Radiology and Oncology, São Paulo, Brazil, 5Pediatric Rheumatology Unit, Universidade Federal de São Paulo, São Paulo, SP, Brazil, 6Federal University of So Paulo (UNIFESP), São Paulo, Brazil, 7Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 8children's institute, Sao Paulo, Brazil, 9University of Sao Paulo, Sao Paulo, Brazil, 10Universidade de Sao Paulo/Rheumatology Division, São Paulo, Brazil, 11UNIFESP, São Paulo, Brazil

    Background/Purpose: The disease activity assessment in c-TA is a challenge in clinical practice, especially in patients who are under immunosuppression. Our aim was to perform…
  • Abstract Number: 0503 • ACR Convergence 2021

    18F-fluorodeoxyglucose Positron Emission Tomography as a Predictor of Angiographic Progression of Disease in Large-vessel Vasculitis

    Kaitlin Quinn1, Mark A. Ahlman2, Hugh Alessi3, Ashkan Malayeri2, Jamie Marko2, Elaine Novakovich2 and Peter Grayson4, 1National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Washington, DC, 2National Institutes of Health, Bethesda, MD, 3National Institutes of Health, Bethesda, Maryland, 4National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD

    Background/Purpose: There is limited prospective data characterizing arterial lesions over time in giant cell arteritis (GCA) and Takayasu’s arteritis (TAK), the two main forms of…
  • Abstract Number: 1194 • ACR Convergence 2021

    A Module on Large Vessel Vasculitis for Learners in Rheumatology

    David Shoemaker1, Stamatina Danielides1, Abhishek Nandan1, Huzaefah Syed2, Beth Rubinstein1 and Seema Patel1, 1Virginia Commonwealth University, Richmond, VA, 2Virginia Commonwealth University Medical Center, Richmond, VA

    Background/Purpose: Of the rheumatic disorders that learners are expected to know, the vasculitides are among the hardest to grasp. Their pathogenesis is not well-established, they…
  • Abstract Number: 1728 • ACR Convergence 2021

    Takayasu’s Arteritis and Pregnancy: A Meta-analysis

    Aine Gorman1, Leah Rooney2, Matthew Turk1, Louise Moore3, Jared Bierbrier4, Celine O'Brien5, Anne Clohessy6, Eamonn Molloy7, Lorraine O Neill8, Fionnuala McAuliffe9 and Douglas Veale10, 1St Vincents Hospital, Dublin, Ireland, 2St Vincent's University Hospital, Dublin, Ireland, 3Our Lady's Hospice and Care Services, Harold's Cross, Dublin 6W, Kinnegad, Ireland, 4McMaster University, Hamilton, ON, Canada, 5Perinatal Research Centre, Obstetrics and Gynaecology, School of Medicine, University College Dublin and National Maternity Hospital, Dublin, Dublin, Ireland, 6National Maternity Hopistal, Dublin, Ireland, 7St Vincent's Healthcare Group, Dublin, Ireland, 8St. Vincent's Hospital, Dublin, Ireland, 9National Maternity Hopsital Dublin, Dublin, Ireland, 10University College Dublin, Dublin, Ireland

    Background/Purpose: Takayasu’s arteritis is a systemic autoimmune disease characterised by large vessel vasculitis. It usually affects women of childbearing age, with 90% of patients diagnosed…
  • Abstract Number: 1862 • ACR Convergence 2021

    Clonal Hematopoiesis Across the Age Spectrum in Patients with Systemic Vasculitis

    Kristina Wells1, Fernanda Gutierrez-Rodrigues2, Bhavisha Patel2, Kaitlin Quinn3, Keith Sikora1, Neal Young4 and Peter Grayson5, 1National Institute of Arthritis, Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, 2National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD, 3National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Washington, DC, 4National Heart, Lung, and Blood Institute (NHLBI), National Institues of Health, Bethesda, MD, 5National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD

    Background/Purpose: Clonal hematopoiesis (CH) is a pre-malignant state characterized by somatic mutations in hematologic precursor cells in genes associated with myeloid malignancies. Incidence of CH…
  • Abstract Number: 1864 • ACR Convergence 2021

    18F-Fluorodeoxyglucose PET/MRI as an Alternative Hybrid Imaging Modality: Comparative Study in a Prospective, Longitudinal Cohort of Patients with Large-Vessel Vasculitis

    Ertugrul Cagri bolek1, Kaitlin Quinn2, Hugh Alessi3, Elaine Novakovich4, Mark A. Ahlman4 and Peter Grayson5, 1Vasculitis Translational Research Program, NIAMS, NIH, US, Lanham, MD, 2National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Washington, DC, 3National Institutes of Health, Bethesda, Maryland, 4National Institutes of Health, Bethesda, MD, 5National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD

    Background/Purpose: Imaging modalities play an important role in the diagnosis and management of patients with large-vessel vasculitis (LVV). Use of 18F-fluorodeoxyglucose (FDG) positron emission tomography…
  • Abstract Number: 1867 • ACR Convergence 2021

    Investigating Adenosine Deaminase 2 Activity in Large Vessel Vasculitis

    Andrew Porter1, Robert Maughan1, Charis Pericleous1, Allan Kiprianos1, Hyuk Jee2, Pui Lee2, Taryn Youngstein1 and Justin Mason1, 1Imperial College London, London, United Kingdom, 2Boston Children's Hospital, Newton, MA

    Background/Purpose: Deficiency of adenosine deaminase 2 (DADA2) leads to a broad phenotype that in some resembles polyarteritis nodosa with fever and rash, but in others…
  • Abstract Number: 1874 • ACR Convergence 2021

    Using 18F-fluorodeoxyglucose Positron Emission Tomography to Standardize Clinical Trial Recruitment in Takayasu’s Arteritis

    Kaitlin Quinn1, Hugh Alessi2, Emily Rose3, Mark A. Ahlman4, Christopher Redmond4, Yiming Luo4, Ertugrul Cagri bolek5, Carol Langford6, Cristina Ponte7, Peter Merkel8 and Peter Grayson9, 1National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Washington, DC, 2National Institutes of Health, Bethesda, Maryland, 3Case Western, Cleveland Heights, OH, 4National Institutes of Health, Bethesda, MD, 5Vasculitis Translational Research Program, NIAMS, NIH, US, Lanham, MD, 6Cleveland Clinic, Moreland Hills, OH, 7Hospital de Santa Maria, Lisbon, Portugal, 8University of Pennsylvania, Philadelphia, PA, 9National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD

    Background/Purpose: Disease activity assessment can be challenging in Takayasu’s arteritis (TAK), which can lead to difficulty in determining eligibility for enrollment into randomized clinical trials…
  • Abstract Number: 0412 • ACR Convergence 2020

    2019 Novel Coronavirus Disease (COVID-19) in Patients with Large-Vessels Vasculitis: Single-centre Experience in Paris

    Chloé Comarmond1, Mathilde Leclercq1, Gaëlle Leroux2, Cindy Marques2, Alexandre Le Joncour3, Fanny Domont2, Céline Hatte1, Ségolène Toquet1, Perrine Guillaume-Jugnot1, Anne-Claire Desbois1, Mathieu Vautier1, Aude Rigolet1, Yves Allenbach4, Olivier Benveniste5, David Saadoun2 and Patrice Cacoub2, 1Assistance Publique des Hopitaux de Paris, Paris, France, 2AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Department of Internal Medicine and Clinical Immunology, F-75013, Paris, France, Centre national de références Maladies Autoimmunes et systémiques rares et Maladies Autoinflammatoires rares, Paris, France, 3APHP, paris, France, 4Sorbonne Université, Paris, Ile-de-France, France, 5Sorbonne Université, paris, France

    Background/Purpose: Advanced age and cardiovascular diseases are recognized as major comorbidities associated with severe forms of coronavirus disease 2019 (COVID-19) caused by the severe acute…
  • Abstract Number: 0418 • ACR Convergence 2020

    Prevalence of Thyroid Disease Among Patients with Vasculitis

    Tanaz Kermani1, David Cuthbertson2, Simon Carette3, Nader Khalidi4, Curry L. Koening5, Carol Langford6, Carol McAlear7, Paul Monach8, Larry Moreland9, Christian Pagnoux10, Philip Seo11, Ulrich Specks12, Antoine Sreih13, Kenneth Warrington12 and Peter Merkel13, 1David Geffen School of Medicine / University of California, Los Angeles, CA, 2University of South Florida, Tampa, 3Division of Rheumatology, Mount Sinai Hospital and University Health Network, University of Toronto, Toronto, ON, Canada, 4McMaster University, Hamilton, ON, Canada, 5University of Utah, Salt Lake City, 6Cleveland Clinic, Moreland Hills, OH, 7University of Pennsylvania, Philadelphia, 8Brigham and Women's, Boston, 9University of Pittsburgh, Denver, CO, 10Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 11Johns Hopkins University, Baltimore, MD, 12Mayo Clinic, Rochester, MN, 13University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Previous studies have reported higher risk of thyroid disease in patients with giant cell arteritis (GCA) and ANCA-associated vasculitis (AAV) compared to age- and…
  • Abstract Number: 0428 • ACR Convergence 2020

    Enrichment of Clinical Trial Recruitment Using Advanced Molecular Imaging in Takayasu’s Arteritis

    Kaitlin Quinn1, Mark Ahlman2, Emily Rose3, Peter Merkel4 and Peter C. Grayson5, 1Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, 2National Institutes of Health, Clinical Center, Radiology and Imaging Sciences, Bethesda, MD, 3Systemic Autoimmunity Branch, Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 4University of Pennsylvania, Philadelphia, PA, 5Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, MD

    Background/Purpose: Definitions of disease activity are not standardized in Takayasu’s arteritis (TAK), which can lead to difficulty in determining whether a patient should be enrolled…
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