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Abstracts tagged "Takayasu.s arteritis"

  • Abstract Number: 1622 • ACR Convergence 2025

    Defective CD4+ regulatory T cells in active Takayasu arteritis patients can be improved by efficiency treatment of tofacitinib

    jing luo1 and Lan He2, 1the first affiliated hospital of xi'an jiaotong university, xi'an, China (People's Republic), 2The First Affiliated Hospital of Xi’an Jiaotong University, Xi'an, China (People's Republic)

    Background/Purpose: To investigate the efficacy of tofacitinib (TOF) in patients with active TAK, explore the effect on CD4+ regulatory T cells (Tregs) homeostasis and relationship…
  • Abstract Number: 1618 • ACR Convergence 2025

    Use of JAK inhibitors in patients with refractory Takayasu arteritis: A worldwide retrospective study

    Fatma Alibaz-Oner1, İbrahim yahya Çakır2, Alessandro Tomelleri3, Aysegul Avcu4, Kaitlin Quinn5, Durga Prasanna Misra6, Matthew Koster7, Peter Grayson8, Alojzija Hocevar9, Kenan Aksu10, Duygu Kerim11, Ertugrul Cağrı Bolek12, Elena Baldissera13, Corrado Campochiaro14, Lorenzo Dagna15, Sema Kaymaz-Tahra16 and Haner Direskeneli4, 1MARMARA UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DIVISION OF RHEUMATOLOGY, Istanbul, Turkey, 2Gazi University, Ankara, 3IRCCS San Raffaele Hospital, Milan, Italy, Milano, Italy, 4Marmara University, Istanbul, Turkey, 5National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, 6Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India, Lucknow, Uttar Pradesh, India, 7Mayo Clinic, Rochester, MN, 8National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Chevy Chase, MD, 9University Medical Center Ljubljana, LJUBLJANA, Slovenia, 10Ege Uni. Tip Fak., Istanbul, Turkey, 11Ege University, Izmir, 12Gazi University, Rheumatology, Ankara, 13IRCCS San Raffaele Hospital, Unit of Immunology, Rheumatology, Allergy and Rare Diseases, Milan, Italy, Milan, 14IRCCS San Raffaele Hospital. Vita-Salute San Raffaele University, Milan, Milan, Italy, 15Ospedale San Raffaele, Milano, Italy, 16Bahcesehir University Faculty of Medicine Department of Internal Medicine Division of Rheumatology, Istanbul, Turkey

    Background/Purpose: Glucocorticoids(GCs) are the mainstay of treatment in Takayasu arteritis (TAK). Conventional DMARDs(cDMARDs) and biologic DMARDS(bDMARDs) are often used as steroid sparing agents in TAK.…
  • Abstract Number: 1614 • ACR Convergence 2025

    A Systematic Literature Review to Inform the EULAR Recommendations for the Management of Polymyalgia Rheumatica and Large Vessel Vasculitis: Focus on Referral and Diagnosis

    Alice Bartoletti1, Georgina Ducker2, Mrinalini Dey3, Durga Prasanna Misra4, Sara Monti5, Bernhard Hellmich6, Chetan Mukhtyar7, Paul Studenic8 and Elena Nikiphorou9, 1Department of Rheumatology, ASST Gaetano Pini CTO, Milan, Italy, Milan, Lombardia, Italy, 2Department of Rheumatology, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, UK, Norwich, England, United Kingdom, 3Department of Rheumatology, King's College Hospital NHS Foundation Trust, London, UK, London, England, United Kingdom, 4Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India, Lucknow, Uttar Pradesh, India, 5University of Pavia, Pavia, Pavia, Italy, 6Department of Internal Medicine, Rheumatology, Pulmonology, Nephrology and Diabetology, Medius Kliniken Kirchheim/Teck, University Tübingen, Tübingen, Germany, Kirchheim-Teck, Germany, 7Norfolk and Norwich University Hospital, Norwich, England, United Kingdom, 8Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, Vienna, Austria, 9King's College London, London, United Kingdom

    Background/Purpose: European Alliance of Associations for Rheumatology (EULAR) recommendations for the management of Polymyalgia Rheumatica (PMR) and Large Vessel Vasculitis (LVV) date back to 2015…
  • Abstract Number: 0764 • ACR Convergence 2025

    Frequency of large vessel vasculitis in giant cell arteritis with and without adventiitis of temporal artery – Is the presence of temporal arteritis sufficient to diagnose giant cell arteritis?-

    Yoichiro Akiyama, Jun Nakamura, Ayako Kokuzawa, Hiroi Kusaka, Sho Tani, Fuminori Taniguchi, Kohei Morikawa, Haruka Kondo, Shotaro Yamamoto, Yasuyuki Kamata and Kojiro Sato, Jichi Medical University, Shimotsuke, Tochigi, Japan

    Background/Purpose: Takayasu arteritis (TAK) and giant cell arteritis (GCA) belong to the large vessel vasculitis group. Differences between the two diseases have been reported based…
  • Abstract Number: 0756 • ACR Convergence 2025

    Stroke Characteristics in Giant Cell Arteritis and Takayasu Arteritis: A Multicenter Cohort Study of 108 Patients

    Omar Dhrif1, Charlotte Caudron2, Simon Parreau3, Eric Liozon3, Adrien Mirouse4, Jean-François Alexandra5, Laurent Sailler6, Mathieu Groh7, Hubert De Boysson8, Mikael Ebbo9, Cloé Comarmond10, Cécile Audrey Durel11, Juliette Woessner12, Pierre-André Jarrot13, Kévin Didier14, Goulabchand Radjiv15, Cacoub Patrice16, Bernard Bonnotte17, David Saadoun16 and Maxime Samson1, 1CHU Dijon Bourgogne, Dijon, France, 2CENTRE HOSPITALIER UNIVERSITAIRE DE DIJON, Paris, France, 3CHU de Limoges, Limoges, France, 4Médecine Interne et Immunologie Clinique, Groupe Hospitalier Pitié-Salpêtrière, APHP, Paris, Paris, France, 5Internal Medicine, Hôpital Bichat, APHP, Paris, France, 6CHU Toulouse, Toulouse, France, 7Hôpital Foch, Suresnes, France, 8Internal Medicine, CHU Caean, Caen, France, 9Internal Medicine, Marseille-APHM, hôpital La Timone, Marseille, France, 10Department of Internal Medicine, Lariboisière University Hospital, Université Paris Cité, Assistance Publique Hôpitaux de Paris, INSERM U942, Paris, France, 11Médecine Interne, Hôpital Saint Joseph Saint Luc, Lyon, Lyon, France, 12Médecine Interne, CH d’Avignon, Avignon, Avignon, France, 13Médecine Interne, Hôpital de la Conception, APHM, Marseille, Marseille, France, 14Médecine Interne, CHU Reims, Reims, Reims, France, 15Médecine Interne, CHU Nîmes, Nîmes, Nîmes, France, 16Department of Internal Medicine and Clinical Immunology, Sorbonne Universités, AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Centre national de références Maladies Autoimmunes et systémiques rares, Centre national de références Maladies Autoinflammatoires rares et Amylose inflammatoire (CEREMAIA), INSERM, UMR S959, Immunology-Immunopathology-Immunotherapy (I3), Paris, France, Paris, France, 17Internal medicine and clinical immunology, Université Bourgogne Europe , CHU Dijon Bourgogne, Dijon, France

    Background/Purpose: In giant cell arteritis (GCA) and Takayasu arteritis (TA), strokes occur in approximately 7.4% and 15.8% of cases, respectively. Although these two large-vessel vasculitides…
  • Abstract Number: 0747 • ACR Convergence 2025

    Patterns of Macrophage Polarization Induced by Serum from Patients with Giant Cell Arteritis and Takayasu’s Arteritis

    Irene Carrión-Barberà1, Ryan D. Stultz2, David Cuthbertson3, Nader Khalidi4, Curry Koening5, Carol Langford6, Carol McAlear7, Paul Monach8, Larry Moreland9, Christian Pagnoux10, Philip Seo11, Kenneth Warrington12, Peter Merkel7 and Christian Lood13, 1Department of Rheumatology. Hospital del Mar, Barcelona, Spain, 2University of Washington, Division of Rheumatology, Seattle, WA, 3University of South Florida, Tampa, 4Department of Medicine, McMaster University and St. Joseph’s Healthcare, Hamilton, Canada, 5University of Texas Dell Medical School, Austin, TX, 6Cleveland Clinic, Moreland Hills, OH, 7University of Pennsylvania, Philadelphia, PA, 8VA Boston Healthcare System, Boston, MA, 9University of Colorado, Denver, CO, 10Mount Sinai Hospital, University Health Network, Toronto, and Canadian Vasculitis Research Network (CanVasc), Toronto, ON, Canada, 11Johns Hopkins University, Baltimore, MD, 12Mayo Clinic, ROCHESTER, MN, 13University of Washington, Division of Rheumatology, Seattle

    Background/Purpose: Macrophages play a central role in the pathogenesis of large-vessel vasculitides, including giant cell arteritis (GCA) and Takayasu’s arteritis (TAK). Characterizing patterns of macrophage…
  • Abstract Number: PP03 • ACR Convergence 2025

    My Journey of Risk, Loss, and Hope: The Role of Multidisciplinary Collaboration in Managing Pregnancy with Takayasu Arteritis

    Tugce Turten Kaymaz

    Background/Purpose: At the age of 26, the same month I got married, I was diagnosed with Takayasu Arteritis following severe chest and back pain. Hypertension…
  • Abstract Number: 2126 • ACR Convergence 2025

    Preliminary Results of a Large, Global Registry Characterizing Childhood-Onset Takayasu Arteritis

    Muserref Kasap Cuceoglu1, James Bistolarides2, Mario Sestan3, Samuel Gagne4, Nick McPhate5, Kimberly Morishita6, Vidya Sivaraman7, Linda Wagner-Weiner8, Seza Özen9, Marija Jelusic10 and David Cabral11, 1Hacettepe University, Ankara, Turkey, 2Medical College of Wisconsin, Wauwatosa, WI, 3University of Zagreb School of Medicine, Zagreb, Croatia, 4University of Pittsburgh, Pittsburgh, PA, 5BC Children's Hospital, Vancouver, Canada, 6University of British Columbia, Vancouver, BC, Canada, 7Nationwide Children's Hospital/ The Ohio State University, Columbus, OH, 8University of Chicago, Chicago, IL, 9Hacettepe University Medical Faculty, Ankara, Turkey, 10University of Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Zagreb, Croatia, 11BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: The rarity of childhood-onset Takayasu arteritis (c-TAK) has resulted in small cohorts for study that has limited the potential for evaluating its course and…
  • Abstract Number: 1632 • ACR Convergence 2025

    PET/CT-Based Distribution of Arterial Involvement and Its Association With Clinical Outcomes in Takayasu Arteritis

    Tokio Katakura1, Tsuyoshi Shirai2, Kentaro Mori1, Mikihiro Takahashi1, Yuito Tanno3, Soshi Okazaki3, So Itoi3, Yosuke Hoshi3, Tomoaki Machiyama3, Yusho Ishii3, Hiroko Sato3 and Hiroshi Fujii3, 1Department of Rheumatology, Tohoku University Hospital, Sendai, Japan, 2Department of Rheumatology, Tohoku University Hospital, Sendai, Miyagi, Japan, 3Department of Rheumatology, Tohoku University Hospital, Sendai

    Background/Purpose: PET/CT enables assessment of active vascular inflammation in Takayasu arteritis (TAK), which is often difficult to evaluate with conventional imaging. Although the distribution of…
  • Abstract Number: 1630 • ACR Convergence 2025

    Validation of the classification algorithm using the modified 2022 ACR/EULAR giant cell arteritis classification criteria and Japanese Takayasu arteritis diagnostic criteria

    Takahiko Sugihara1, Masayoshi Harigai2, Haruhito Uchida3, Yasuhiro Maejima4, Hajime Yoshifuji5, Yoshiko Watanabe6, Yasuhiro Onishi3, Shunsuke Furuta7, Tomonori Ishii8, Tsuyoshi Shirai9, Taio Naniwa10, Noriyoshi Ogawa11, Yuko Kaneko12, Hiroaki Dobashi13, Koichi Amano14, Jun Ishizaki15, Takako Miyamae16, Shuichi Ito17, Yoshinori Komagata18, Naoto Tamura19 and Yoshikazu Nakaoka20, 1Division of Rheumatology, Department of Internal Medicine, Toho University School of Medicine, Tokyo, Japan, 2Department of Rheumatology, International University of Health and Welfare, Tokyo, Japan, 3Department of Chronic Kidney Disease and Cardiovascular Disease, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan, 4Department of Cardiovascular Medicine, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan, 5Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan, 6Department of General Medicine, Kawasaki Medical School, Kurashiki,, Japan, 7Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan, 8Division of Hematology and Rheumatology, Tohoku Medical and Pharmaceutical University, Sendai, Japan, 9Department of Rheumatology, Tohoku University Hospital, Sendai, Miyagi, Japan, 10Division of Rheumatology, Department of Internal Medicine, Nagoya City University Hospital, Nagoya, Japan, 11Department of Internal Medicine 3, Hamamatsu University School of Medicine, Hamamatsu, Japan, 12Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 13Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University, Miki-cho, Kita-gun, Kagawa, Japan, 14Department of rheumatology and clinical Immunology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan, 15Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine, Ehime, Japan, 16Department of Pediatric Rheumatology, Institute of Rheumatology, Tokyo Women’s Medical University Hospital, Tokyo, Japan, 17Department of Pediatrics, Yokohama City University School of Medicine, Yokohama, Japan, 18Department of Nephrology and Rheumatology, Kyorin University School of Medicine, Tokyo, Japan, 19Juntendo University School of Medicine, Tokyo, Japan, 20Department of Vascular Physiology, National Cerebral and Cardiovascular Center Research Institute,, Suita, Japan

    Background/Purpose: Given the increasing number of patients with giant cell arteritis (GCA) in Japan and the higher incidence of Takayasu arteritis (TAK) compared to Europe…
  • Abstract Number: 1631 • ACR Convergence 2025

    New Arterial Damage in Takayasu’s Arteritis

    Tanaz Kermani1, Sema Kaymaz-Tahra2, Aysegul Avcu3, Fatma Alibaz-Oner4, Haner Direskeneli3 and Peter Merkel5, 1University of California Los Angeles, Santa Monica, CA, 2Bahcesehir University Faculty of Medicine Department of Internal Medicine Division of Rheumatology, Istanbul, Turkey, 3Marmara University, Istanbul, Turkey, 4MARMARA UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DIVISION OF RHEUMATOLOGY, Istanbul, Turkey, 5University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Damage is one of the consequences of disease and is often considered irreversible. This study aimed to evaluate new arterial damage in Takayasu’s arteritis…
  • Abstract Number: 1627 • ACR Convergence 2025

    A systematic literature review to inform the 2025 EULAR recommendations for management of Polymyalgia Rheumatica and Large Vessel Vasculitis: management of disease including relapse and complications

    Mrinalini Dey1, Durga Prasanna Misra2, Alice Bartoletti3, Georgina Ducker4, Sara Monti5, Bernhard Hellmich6, Chetan Mukhtyar7, Paul Studenic8 and Elena Nikiphorou9, 1Centre for Rheumatic Diseases, King's College London, London, United Kingdom, 2Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India, Lucknow, Uttar Pradesh, India, 3ASST Gaetano Pini CTO, Cremona, Italy, 4Department of Rheumatology, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, UK, Norwich, England, United Kingdom, 5University of Pavia, Pavia, Pavia, Italy, 6Department of Internal Medicine, Rheumatology, Pulmonology, Nephrology and Diabetology, Medius Kliniken Kirchheim/Teck, University Tübingen, Tübingen, Germany, Kirchheim-Teck, Germany, 7Norfolk and Norwich University Hospital, Norwich, England, United Kingdom, 8Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, Vienna, Austria, 9King's College London, London, United Kingdom

    Background/Purpose: EULAR recommendations informing the management of Polymyalgia Rheumatica (PMR) and Large Vessel Vasculitis (LVV) were previously published separately in 2015 [1] and 2020 [2]…
  • Abstract Number: 0765 • ACR Convergence 2024

    Tocilizumab in Extracranial Large-Vessel Giant Cell Arteritis and Takayasu Arteritis: A Multicentric Observational Comparative Study

    Carmen Lasa Teja1, Javier Loricera2, Diana Prieto-Peña3, fernando lopez gutierrez4, Pilar Bernabéu5, Mercedes Freire González6, ivan Ferraz-Amaro7, Santos Castañeda8, Mauricio Mínguez9, Beatriz bravo-Mancheño10, Roser Solans-Laqué11 and Ricardo Blanco-Alonso12, 1Hospital Universitario Marqués de Valdecilla, Riotuerto, Spain, 2Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 3Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Cantabria, Spain, 4Rheumatology, madrid, Madrid, Spain, 5Rheumatology section, Dr. Balmis General University Hospital-ISABIAL, Alicante, Spain, Alicante, Spain, 6Complexo Hospitalario Universitario de A Coruña, La coruna, Galicia, Spain, 7Rheumatology, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Canarias, Spain, 8Hospital Universitario de la Princesa, Madrid, Spain, 9Hospital San Juan de Alicante, Rheumatology., Alicante, Spain, 10Hospital Universitario Virgen de las Nieves, Granada, Granada., Spain, 11Internal Medicine Service, Vall d'Hebron Hospital University and Campus, Barcelona, Spain, 12Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain

    Background/Purpose: Tocilizumab (TCZ) seems to be effective in large vessel (LV) vasculitis including giant cell arteritis (GCA) and Takayasu arteritis (TAK). LV-GCA phenotype shares some…
  • Abstract Number: 1561 • ACR Convergence 2024

    Association of Large Vessel Vasculitis and Development of SSc and SSc-Associated Antibodies: Impact of Pulmonary Arterial Hypertension

    Brett Dinner1, Ahmed Abdelmaksoud2, Ann Igoe3, Taylor Viggiano4 and Vivek Nagaraja5, 1Creighton University, Paradise Valley, AZ, 2University of California, Riverside, Riverside, CA, 3Flow, Tempe, AZ, 4Mayo Clinic, Phoenix, 5Mayo Clinic Arizona, Scottsdale, AZ

    Background/Purpose: Large vessel vasculitis (LVV) comprises a spectrum of rare, potentially life-threatening disorders, including giant cell arteritis (GCA) and Takayasu's arteritis (TAK), defined by granulomatous…
  • Abstract Number: 1615 • ACR Convergence 2024

    Is Regular Vascular Imaging Scheduled Essential in the Follow-Up of Takayasu Arteritis? A Large-Scale Multicenter Cohort Study

    Fatih Yildirim1, Cemal Bes2, Muhammet Emin Kutu3, Fatih Tastekin4, Gokhan Keser5, Tugba Ocak6, Ediz Dalkilic6, Yavuz Pehlivan6, Hasan Kocaayan7, Servet Akar7, Sema İsik8, Ahmet Omma9, Senar San10, Ayten Yazici11, Ayse Cefle11, Safiye Bakkal12, Gökçe Kenar13, Fatos Onen12, Aysegül Avcu14, Fatma Alibaz Öner15, Haner Direskeneli15, Burcu Ceren Uludogan16, Nazife Sule yaşar Bile16 and Nilüfer Alpay Kanıtez17, 1University of Health Sciences Başakşehir Çam and Sakura City Hospital, İstanbul, Turkey, İstanbul, Turkey, 2University of Health Sciences Başakşehir Çam and Sakura City HospitalUniversity of Health Sciences Başakşehir Çam and Sakura City Hospital, İstanbul, Turkey, İstanbul, Turkey, 3Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey, 4Ege University School of Medicine, Rheumatology, İzmir, Turkey, İzmir, Turkey, 5Ege University School of Medicine, Rheumatology, İzmir, Turkey, Izmir, Turkey, 6Uludağ University Faculty of Medicine, Rheumatology, Bursa, Turkey, Bursa, Turkey, 7İzmir Katip Celebi University School of Medicine, Rheumatology, İzmir, Turkey, İzmir, Turkey, 8University of Health Sciences Ankara Bilkent City Hospital, Rheumatology, Ankara, Turkey, Ankara, Turkey, 9Ankara Bilkent City Hospital, Ankara, Turkey, 10Kocaeli University Faculty of Medicine, Rheumatology, Kocaeli, Turkey, Kocaeli, Turkey, 11Kocaeli University Faculty of Medicine, Kocaeli, Turkey, Kocaeli, Turkey, 12Dokuz Eylul University Faculty of Medicine, İzmir, Turkey, İzmir, Turkey, 13Dokuz Eylul University School of Medicine, Izmir, Turkey, 14Marmara University Faculty of Medicine, Rheumatology, İstanbul, Turkey, İstanbul, Turkey, 15Marmara University Faculty of Medicine, Rheumatology, İstanbul, Turkey, Istanbul, Turkey, 16Osmangazi University Faculty of Medicine, Rheumatology, Eskişehir, Turkey, Eskisehir, Turkey, 17Koc University Faculty of Medicine, Rheumatology, İstanbul, Turkey, Istanbul, Turkey

    Background/Purpose: The understanding of progression or minimal disease activity in patients with Takayasu arteritis (TA) can be complicated due to the possibility of mild vascular…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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