Abstracts tagged "Takayasu arteritis"

Abstract Number: 1964 • 2019 ACR/ARP Annual Meeting
A Role for Microbiota in the Pathophysiology of Takayasu Arteritis (TAK) and Giant Cell Arteritis (GCA)
Anne Desbois¹, Dragos Ciocan ², David Saadoun ¹, Gabriel Perlemuter ³ and Patrice Cacoub ⁴, ¹GHPS, Paris, France, ²Hôpital Antoine Beclere, Clamart, France, ³Hôpital Clamart, Paris, France, ⁴AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Department of Internal Medicine and Clinical Immunology, F-75013, Paris, France, Paris, France
Background/Purpose: The pathogenesis of Large Vessel Vasculitis (LVV) is not well understood. There is increasing evidence of a close link between intestinal dysbiosis and systemic…
Abstract Number: 2740 • 2019 ACR/ARP Annual Meeting
Takayasu Arteritis Associated Risk Locus in IL6 Represses the Anti-inflammatory Gene GPNMB Through Chromatin Looping and Recruiting MEF2-HDAC Complex
Xiufang Kong ¹ and Amr Sawalha², ¹University of Michigan & Fudan University, Ann Arbor, MI, ²University of Pittsburgh & University of Michigan, Pittsburgh, PA
Background/Purpose: Previous work has revealed a genetic association between Takayasu arteritis and a non-coding genetic variant in an enhancer region within IL6 (rs2069837 A/G). The…
Abstract Number: 2919 • 2019 ACR/ARP Annual Meeting
Endothelial Protein C Receptor and Scavenger Receptor Class B Type 1 Negatively Regulate Vascular Inflammation and Are Major Autoantigens in Takayasu Arteritis
Tomoyuki Mutoh¹, Tsuyoshi Shirai ¹, Tomonori Ishii ², Yuko Shirota ³, Hideo Harigae ¹ and Hiroshi Fujii ¹, ¹Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan, ²Tohoku University Hospital, Sendai, Japan, ³Department of Hematology and Rheumatology, Tohoku Medical and Pharmaceutical University, Sendai, Japan
Background/Purpose: Takayasu arteritis (TAK) is a chronic vasculitis which predominantly affects large vessels. Although anti-endothelial cell antibodies (AECA) had been reported to be involved in…
Abstract Number: 2920 • 2019 ACR/ARP Annual Meeting
Comparison of Arterial Patterns of Disease in Takayasu’s Arteritis and Giant Cell Arteritis
K Bates Gribbons¹, Cristina Ponte ², Anthea Craven ³, David Cuthbertson ⁴, Simon Carette ⁵, Gary S. Hoffman ⁶, Nader A. Khalidi ⁷, Curry L. Koening ⁸, Carol Langford ⁹, Kathleen Maksimowicz-McKinnon ¹⁰, Carol A. McAlear ¹¹, Paul Monach ¹², Larry Moreland ¹³, Christian Pagnoux ¹⁴, Kaitlin Quinn ¹⁵, Joanna Robson ¹⁶, Philip Seo ¹⁷, Antoine Sreih ¹⁸, Ravi Suppiah ¹⁹, Kenneth Warrington ²⁰, Steven Ytterberg ²¹, Raashid Luqmani ³, Richard Watts ²², Peter Merkel ¹⁸ and Peter C. Grayson ²³, ¹National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ²Department of Rheumatology, Hospital de Santa Maria, Lisbon, Portugal, ³University of Oxford, Oxford, United Kingdom, ⁴University of South Florida, Tampa, FL, ⁵Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, Canada, ⁶Cleveland Clinic Foundation, Cleveland, OH, ⁷McMaster University, Hamilton, ON, Canada, ⁸University of Utah Hospital, Salt Lake City, UT, ⁹Cleveland Clinic, Cleveland, OH, ¹⁰Henry Ford Hospital, Wayne State University, Detroit, MI, ¹¹University of Pennsylvania - VCRC Project Manager, Philadelphia, PA, ¹²Brigham and Women's Hospital, Boston, MA, ¹³University of Pittsburgh, PITTSBURGH, PA, ¹⁴Mount Sinai Hospital and University Health Network, Toronto, ON, Canada, ¹⁵Georgetown University Hospital/National Institutes of Health, Washington, DC, ¹⁶Faculty of Health and Applied Sciences, University of the West of England, Bristol, United Kingdom, ¹⁷Johns Hopkins Medicine, Baltimore, MD, ¹⁸University of Pennsylvania, Philadelphia, PA, ¹⁹Department of Rheumatology, Auckland District Health Board, Auckland, New Zealand, ²⁰Mayo Clinic Rochester, Rochester, MN, ²¹Mayo Clinic College of Medicine, Rochester, MN, ²²Norwich Medical School, University of East Anglia, Norwich, United Kingdom, ²³National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD
Background/Purpose: Current classification criteria differentiate between Takayasu’s arteritis (TAK) and giant cell arteritis (GCA), the two most common forms of large-vessel vasculitis, based primarily on…
Abstract Number: 779 • 2017 ACR/ARHP Annual Meeting
Assessment of Treatment Response By 18f-Fludeoxyglucose Positron Emission Tomography (FDG-PET) in Patients with Large Vessel Vasculitis (LVV)
Shubhasree Banerjee¹, Sara Alehashemi², Ali Cahid Civelek³, Elaine Novakovich⁴, Armin Bagheri⁵, Ashkan Malayeri³, Mark Ahlman³ and Peter C. Grayson⁶, ¹Fellowship and training branch, NIAMS/NIH, Bethesda, MD, ²Rheumatology, National Institutes of Health, Bethesda, MD, ³Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, ⁴Systemic Autoimmunity Branch, NIAMS, National Institutes of Health, Bethesda, MD, ⁵Vasculitis Translational Research Program, NIAMS, NIH, Bethesda, MD, ⁶Research, National Institutes of Health, Bethesda, MD
Background/Purpose: Disease activity in large vessel vasculitis (LVV) is traditionally assessed by clinical and serological (ESR, CRP) parameters. Imaging assessment, including FDG-PET, may also be…
Abstract Number: 901 • 2016 ACR/ARHP Annual Meeting
Clinical Features of Takayasu’s Arteritis from an Inception Cohort: Early Disease Is Characterized By ‘systemic Inflammation’
Fatma Alibaz-Oner¹, Ali Ugur Unal², Ahmet Mesut Onat³, Bunyamin Kisacik⁴, Orhan Zengin⁵, Omer Karadag⁶, Abdulsamet Erden⁶, Handan Yarkan⁷, Servet Akar⁸, Fatih Yildiz⁹, Eren Erken¹⁰, Huseyin Özer¹¹, Ahmet Omma¹², Zeynep Ozbalkan¹³, Yasar Karaaslan¹⁴, Cemal Bes¹⁵, Sibel Yilmaz Oner¹⁵, Nilufer Alpay Kanitez¹⁵, Ozun Bayndır¹⁶, Sule Yavuz¹⁷, Nursen Duzgun¹⁸, Ayse Nur Tufan¹⁹, Ediz Dalkilic¹⁹, Hajime Yoshifuji²⁰, Abdurrahman Tufan¹⁷, Lutfi Akyol²¹, Mehmet Akif Ozturk²², Mehmet Sayarlioglu²³, Kenan Aksu¹⁶, Gokhan Keser²⁴, Sedat Kiraz²⁵, Omer Nuri Pamuk²⁶, Fatos Onen²⁷ and Haner Direskeneli²⁸, ¹Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, ²Marmara University, School of Medicine, Rheumatology, Istanbul, Turkey, ³Department Of Internal Medicine, Division of Rheumatology, Gaziantep University, Gaziantep University,Division of Rheumatology, Gaziantep, Turkey, ⁴Rheumatology Department, Gaziantep University School of Medicine, Gaziantep, Turkey, ⁵Rheumatology, Gaziantep University School of Medicine, Gaziantep, Turkey, ⁶Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, ⁷Rheumatology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey, ⁸Department of Rheumatology, İzmir Katip Çelebi University, School of Medicine, İzmir, Turkey, İzmir, Turkey, ⁹Rheumatology, Van EAH, Adana, Turkey, ¹⁰Rheumatology, Cukurova University Faculty of Medicine, Adana, Turkey, ¹¹Rheumatology, Cukurova Univesity, School of Medicine, Adana, Turkey, ¹²Department of Internal Medicine, Rheumatology Division, Ankara Numune Hospital, Ankara, Turkey, ¹³Rheumatology Departent, MD,Assoc. Prof., Ankara, Turkey, ¹⁴Rheumatology, Turkish Takayasu's Arteritis Study Group, Istanbul, Turkey, ¹⁵Rheumatology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey, ¹⁶İnternal Medicine Division of Rheumatology, Ege University Medical Faculty, Izmir, Turkey, ¹⁷PsART study group, Ankara, Turkey, ¹⁸Internal Medicines, Rheumatology Department, Ankara University School of Medicine, Ankara, Turkey, ¹⁹Rheumatology, Uludag University Medcal Faculty, Bursa, Turkey, ²⁰Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan, ²¹Department of Internal Medicine Division of Rheumatology, Ondokuz Mayıs University, Faculty of Medicine, Samsun, Turkey, ²²Internal Medicine-Rheumatology, Gazi University Medical School, Ankara, Turkey, ²³Rheumatology, Ondokuz Mayis University School of Medicine, Samsun, Turkey, ²⁴Rheumatology, Ege University Medical Faculty, Izmir, Turkey, ²⁵Hacettepe University Vasculitis Center (HUVAC), Ankara, Turkey, ²⁶Department of Rheumatology, Trakya University School of Medicine, Edirne, Turkey, ²⁷Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, ²⁸Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey
Background/Purpose: There is only retrospective and very limited data for the long term prognosis of Takayasu's Arteritis (TAK), a rare large-vessel vasculitis. In this study,…
Abstract Number: 979 • 2016 ACR/ARHP Annual Meeting
A Randomized Double-Blind Trial of Abatacept and Glucocorticoids for the Treatment of Takayasu’s Arteritis
Carol A. Langford¹, David Cuthbertson², Steven R. Ytterberg³, Nader A. Khalidi⁴, Paul A. Monach⁵, Simon Carette⁶, Philip Seo⁷, Larry W. Moreland⁸, Michael Weisman⁹, Curry L. Koening¹⁰, Antoine G. Sreih¹¹, Robert F. Spiera¹², Carol A McAlear¹³, Kenneth J. Warrington³, Christian Pagnoux¹⁴, Kathleen Maksimowicz-McKinnon¹⁵, Lindsy J. Forbess⁹, Gary S. Hoffman¹⁶, Renee Borchin¹⁷, Jeffrey Krischer¹⁷ and Peter A. Merkel¹⁸, ¹Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, ²Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL, ³Rheumatology, Mayo Clinic, Rochester, MN, ⁴McMaster University, St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, ⁵Rheumatology, Boston University School of Medicine, Boston, MA, ⁶Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁷Division of Rheumatology, Johns Hopkins University, Baltimore, MD, ⁸Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ⁹Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ¹⁰Rheumatology, University of Utah, Salt Lake City, UT, ¹¹Department of Rheumatology, University of Pennsylvania, Philadelphia, PA, ¹²Hospital for Special Surgery, Cornell, New York, NY, ¹³Penn Vasculitis Center, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, ¹⁴Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ¹⁵Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ¹⁶Rheumatology, Cleveland Clinic, Cleveland, OH, ¹⁷University of South Florida, Tampa, FL, ¹⁸Division of Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Takayasu’s arteritis (TAK) is a large-vessel primary systemic vasculitis that affects the aorta, its branches, and the pulmonary arteries. Despite treatment with glucocorticoids, relapse…
Abstract Number: 1287 • 2016 ACR/ARHP Annual Meeting
Utility of Vascular Findings By PET/CT Scan in the Diagnosis and Activity Assesment of Takayasu Arteritis
Bahtiyar Toz¹, Zeynep Gözde Özkan², Bahar Artim-Esen¹, Burak Erer¹, Sevil Kamali³, Ahmet Gul¹, Lale Ocal³ and Murat Inanc⁴, ¹Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ²Department of Nuclear Medicine,, Istanbul Faculty of Medicine, Istanbul, Turkey, Istanbul, Turkey, ³Department of Internal Medicine, Rheumatology Division, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ⁴Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, İstanbul, Turkey
Background/Purpose: Takayasu arteritis (TA) is a large-vessel vasculitis predominantly affecting the aorta and its main branches. Assessing disease activity is difficult and mainly based on…
Abstract Number: 3062 • 2015 ACR/ARHP Annual Meeting
Frequency, Presentation and Outcome of Takayasu Arteritis in Western Australia
Krista Makin¹, Maxine Garnsey² and Johannes Nossent³, ¹Rheumatology, Fiona Stanley Hospital, Murdoch, Australia, ²Internal Medicine, Sir Charles Gairdner Hospital, Nedlands, Australia, ³Medicine, University of Western Australia, WA, Australia
Background/Purpose: Takayasu Arteritis (TAK) is a systemic large-vessel vasculitis that mostly affects women of childbearing age. The worldwide incidence of TAK varies due to genetic…
Abstract Number: 3067 • 2015 ACR/ARHP Annual Meeting
Microscopic Colitis in Patients with Takayasu Arteritis; A Potential Association Between the Two Disease Entities
Nilufer Alpay Kanitez¹, Bahtiyar Toz¹, Mine Gulluoglu², Burak Erer^1,3, Murat Inanc⁴, Bilger Cavus⁵, Raim Iliaz⁵, Cetin Karaca⁵ and Sevil Kamali¹, ¹Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ²Pathology, Istanbul University, Istanbul Faculty of Medicine, Ä°stanbul, Turkey, ³Department of Internal Medicine, Rheumatology Division, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ⁴Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Ä°stanbul, Turkey, ⁵Department of Internal Medicine, Division of Gastroenterology, Istanbul University, Istanbul Faculty of Medicine, Ä°stanbul, Turkey
Background/Purpose: Takayasu's arteritis (TAK) is a chronic vasculitis of large-vessels, mainly affects the aorta and its branches in the middle-aged females. There are reports regarding…
Abstract Number: 810 • 2014 ACR/ARHP Annual Meeting
Damage Assessment in Takyasu Arteritis Using Takayasu Arteritis Damage Score (TADS)
Debashish Danda¹, Ruchika Goel², Raheesh Ravindran² and George Joseph³, ¹Clinical Immunology& Rheum, Christian Medical College, Vellore Tamilnadu, India, ²Clinical Immunology & Rheumatology, Christian Medical College & Hospital, Vellore, India, Vellore, India, ³Cardiology, Christian Medical College & Hospital, Vellore, India, Vellore, India
Background/Purpose Takayasu arteritis (TA) is a prototype large vessel vasculitis. Assessment of disease activity and damage has been challenging in TA due to lack of…
Abstract Number: 801 • 2014 ACR/ARHP Annual Meeting
Venothromboembolism in Large Vessel Vasculitis
Sankalp V. Bhavsar¹, Nader A. Khalidi², Simon Carette³, David Cuthbertson⁴, Peter C. Grayson⁵, Gary S. Hoffman⁶, Curry L. Koening⁷, Carol A. Langford⁸, Carol McAlear⁹, Larry Moreland¹⁰, Paul A. Monach¹¹, Christian Pagnoux³, Philip Seo¹², Kenneth J. Warrington¹³, Steven R. Ytterberg¹³ and Peter A. Merkel¹⁴, ¹Division of Rheumatology, McMaster University, Hamilton, ON, Canada, ²Division of Rheumatology, St. Joseph’s Hospital, McMaster University, Hamilton, ON, Canada, ³Division of Rheumatology, University of Toronto, Toronto, ON, Canada, ⁴Department of Biostatistics, University of South Florida, Tampa, FL, ⁵NIAMS Systemic Autoimmunity Branch, National Institutes of Health, Bethesda, MD, ⁶Center for Vasculitis Care and Research, Cleveland Clinic Foundation, Cleveland, OH, ⁷Division of Rheumatology, University of Utah, Salt Lake City, UT, ⁸Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, OH, ⁹Division of Rheumatology, Vasculitis Center, University of Pennsylvania, Philadelphia, PA, ¹⁰Vasculitis Center, of University of Pittsburgh Medical Center, Pittsburgh, PA, ¹¹Section of Rheumatology, Vasculitis Center, Boston University School of Medicine, Boston, MA, ¹²Rheumatology Division, Johns Hopkins Vasculitis Center, Johns Hopkins University, Baltimore, MD, ¹³Division of Rheumatology, Mayo Clinic, Rochester, MN, ¹⁴University of Pennsylvania, Philadelphia, PA
Background/Purpose: Venous thromboembolic disease (VTE) is a recognized characteristic of various systemic vasculitides, particularly small-vessel vasculitis. However, there are no reports describing the frequency of…
Abstract Number: 1686 • 2013 ACR/ARHP Annual Meeting
Tocilizumab In Refractory Takayasu Arteritis: a Case Series and Updated Literature Review.²
Noemie Abisror¹, Arsene Mekinian², Christian Lavigne³, Marie Anne Vandenhende⁴, Michael Soussan⁵ and Olivier Fain¹, ¹Internal Medicine, Jean Verdier Hospital, Bondy, France, ²Internal Medicine, Jean Verdier Hospital, Bondy, FL, France, ³Internal Medicine, Angers, France, ⁴Internal Medicine, Bordeaux, France, ⁵Nuclear Medicine, Avicennes Hospital, Bobigny, France
Tocilizumab in refractory Takayasu arteritis: a case series and updated literature review.Background/Purpose: The aim of this study is to analyze the efficacy and tolerance of…
Abstract Number: 1681 • 2013 ACR/ARHP Annual Meeting
Assessment of Patients With Takayasu’s Arteritis in Routine Clinical Follow-Up With Indian Takayasu Clinical Activity Score 2010(ITAS2010)
Fatma Alibaz-Oner and Haner Direskeneli, Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey
Background/Purpose: ITAS2010 (Indian Takayasu Clinical Activity Score) is a new composite index developed to assess clinical activity in Takayasu’s arteritis (TAK), which is weighted for…
Abstract Number: 1680 • 2013 ACR/ARHP Annual Meeting
Predictivity Of Serum Biomarkers For Disease Activity In a Prospectively Followed-Up Takayasu Arteritis Cohort: Is Serum Amyloid A Protein Better Than Conventional Acute Phase Markers?
Ahmet Omma¹, Burak Erer², Nilufer Alpay³, Nuray Gurel Polat⁴, Ahmet Gul¹, Murat Inanc⁴, Lale Ocal¹ and Sevil Kamali¹, ¹Department of Internal Medicine, Rheumatology Division, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ²Department of Internal Medicine, Rheumatology Division, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey, ³Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ⁴Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey
Background/Purpose: Takayasu arteritis (TA) is a chronic vasculitis with an indolent course. Reliable diagnostic and activity markers have not yet been demonstrated. We aimed to…

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