Abstracts tagged "TACI and autoantibodies"

Abstract Number: 1117 • ACR/ARHP Annual Meeting 2015
The B Cell Survival Cytokine BAFF Promotes Systemic Lupus Erythematosus Via Activation of TACI, Not BAFF Receptor
Holly Jacobs¹, Christopher Thouvenel¹, Tanvi Arkatkar¹, Nicole Scharping¹, David Rawlings² and Shaun Jackson¹, ¹Seattle Children's Research Institute, Seattle, WA, ²Pediatrics/Immunology, Washington, Seattle, WA
Background/Purpose: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by polyclonal B cell activation and production of class-switched antinuclear antibodies (ANA). Transgenic mice…