Abstract Number: 3110 • 2016 ACR/ARHP Annual Meeting
Rab4A Is Required for Development of Tregs, Restricts Antiphospholipid Antibody Production and Pro-Inflammatory Expansion of Macrophages and Neutrophils, and Blocks Pristane-Induced Intra-Alveolar Hemorrhage in a Mouse Model of SLE
Background/Purpose: Polymorphic haplotypes of the HRES-1 endogenous retrovirus at the 1q42 chromosomal locus have been associated with lupus susceptibility, in particular, with predisposition to antiphospholipid…