Abstracts tagged "T cells and transcription factor"

Abstract Number: 1907 • 2016 ACR/ARHP Annual Meeting
T-Bet Regulates Ahr-Mediated Th-17 Differentiation Independently of IFNγ
Masahiro Yokosawa, Yuya Kondo, Shunta Kaneko, Seiji Segawa, Hiroto Tsuboi, Isao Matsumoto and Takayuki Sumida, Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Background/Purpose: Our previous reports showed that the development of collagen-induced arthritis was suppressed in T-bet transgenic (T-bet Tg) mice. The regulatory mechanism might relate to…
Abstract Number: 2741 • 2014 ACR/ARHP Annual Meeting
The Role of Fli1 in Lupus T Cell Function and Nephritis
Thirumagal Thiyagarajan¹, Ivan Molano² and Tamara K. Nowling³, ¹Medicine, Medical University of South Carolina, Charleston, SC, ²Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC, ³Medicine/Rheumatology, Medical University of South Carolina and Ralph H. Johnson VA Medical Center, Charleston, SC
Background/Purpose: The Ets factor Fli1 is implicated as a key modulator of lupus disease expression. Over-expressing Fli1 in healthy mice, results in the development of…

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