Abstracts tagged "T cells and osteoclastogenesis"

Abstract Number: 1753 • 2014 ACR/ARHP Annual Meeting
Human T-Cells Express RANKL in Response to Combination of ZAP-70, Calcineurin and Voltage-Gated K+-Channel Signaling Following Co-Ligation of the Adhesion Molecule CD2 and the T-Cell Receptor Complex
Bohdan P. Harvey and Zehra Kaymakcalan, Biologics, AbbVie Bioresearch Center, Worcester, MA
Background/Purpose Human T lymphocytes promote osteolysis in rheumatic diseases through the production of the osteoclastogenic cytokine RANKL. We have previously demonstrated that RANKL secretion is…

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Abstracts tagged "T cells and osteoclastogenesis"

Human T-Cells Express RANKL in Response to Combination of ZAP-70, Calcineurin and Voltage-Gated K+-Channel Signaling Following Co-Ligation of the Adhesion Molecule CD2 and the T-Cell Receptor Complex