Abstracts tagged "T cells and dendritic cells"

Abstract Number: 716 • 2013 ACR/ARHP Annual Meeting
The Active Metabolite Of Spleen Tyrosine Kinase Inhibitor Fostamatinib Abrogates The T Cell Priming Capacity Of Dendritic Cells
Andrew Platt¹, Ross McQueenie¹, Robert Benson², John Butcher¹, Martin Braddock³, James M. Brewer⁴, Iain B. McInnes¹ and Paul Garside¹, ¹Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom, ²Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom, ³AstraZeneca R&D Alderley Park, Macclesfield, United Kingdom, ⁴Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom
Background/Purpose: Spleen tyrosine kinase (SYK) is a core signaling protein that drives inflammatory responses and is fundamental to the propagation of signals via numerous immune-receptors…

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Abstracts tagged "T cells and dendritic cells"

The Active Metabolite Of Spleen Tyrosine Kinase Inhibitor Fostamatinib Abrogates The T Cell Priming Capacity Of Dendritic Cells