Abstracts tagged "T cells and atherosclerosis"

Abstract Number: 644 • 2013 ACR/ARHP Annual Meeting
Expansion Of CD4⁺CXCR3⁺ T Cells In Patients With Systemic Lupus Erythematosus (SLE) Correlates With Subclinical Atherosclerosis
Karim Sacre¹, Brigitte Escoubet², Nicolas Charles³, Antoine Dossier⁴, Marie-Paule Chauveheid⁵ and Thomas Papo¹, ¹Internal Medicine, University Paris-7, INSERM U699, APHP, Bichat Hospital, Paris, France, ²Cardiology, University Paris-7, INSERM U872, APHP, Bichat Hospital, Paris, France, ³INSERM U699, Paris, France, ⁴Internal Medicine, University Paris-7, APHP, Bichat Hospital, Paris, France, ⁵Internal Medicine,, University Paris-7, APHP, Bichat Hospital, Paris, France
Background/Purpose: The mechanisms for accelerated atherosclerosis in SLE remain unclear. As atherosclerosis is itself immune-mediated, features of SLE-associated immunity might explain accelerated cardiovascular disease beside traditional…
Abstract Number: 640 • 2013 ACR/ARHP Annual Meeting
Systemic Lupus Erythematosus Patients With Atherosclerosis Are Characterised By a Distinct Invariant Natural Killer T Cell Phenotype and Altered CD1d-Mediated Lipid Antigen Presentation
Edward Smith¹, Sara Croca², Andrew Pitcher¹, D.A. Isenberg¹, Anisur Rahman³ and Elizabeth C. Jury⁴, ¹Centre for Rheumatology Research, University College London, London, United Kingdom, ²Centre for Rheumatology Research, Division of Medicine, University College London, London, United Kingdom, ³Centre for Rheumatology Research,Rayne Institute, 4th Floor, University College London, London, United Kingdom, ⁴Division of Medicine, Centre for Rheumatology Research, University College London, London, United Kingdom
Background/Purpose: It is widely reported that systemic lupus erythematosus (SLE) patients have an increased risk of atherosclerosis compared to the general population, irrespective of traditional…

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