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Abstracts tagged "T cells and ankylosing spondylitis (AS)"

  • Abstract Number: 1675 • ACR/ARHP Annual Meeting 2016

    Triptolide Inhibits Th17 Differentation By JAK2/STAT3 Signal Pathway in Inflammation of Ankylosing Spondylitis

    Hongxiao Liu1, Junyao Song1, Ziqi Xu1, Xinghua Feng1, Quan Jiang2 and YaNan Zhao3, 1Department of Rheumatology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China, 2Rheumatology Department, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China, 3Department of Rheumatology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, BeiJing, China

    Background/Purpose: Th17 plays important role in pathogenesis of AS inflammation, and its main effector, IL-17, was the critical effector on mediating it. Activated of Th17…
  • Abstract Number: 2821 • ACR/ARHP Annual Meeting 2015

    Increased CD4 T Cell GM-CSF Production in Spondyloarthritis

    M Hussein Al-Mossawi1, Jelle De Wit2, Anna Ridley3 and Paul Bowness1, 1Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 2Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 3Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, United Kingdom

    Background/Purpose: Immunological, genetic and therapeutic studies have implicated the IL-17A/IL-23 inflammatory axis in SpA.  GM-CSF is emerging as a cytokine that marks out a pathogenic…

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