Abstracts tagged "T cells and ankylosing spondylitis (AS)"

Abstract Number: 1675 • 2016 ACR/ARHP Annual Meeting
Triptolide Inhibits Th17 Differentation By JAK2/STAT3 Signal Pathway in Inflammation of Ankylosing Spondylitis
Hongxiao Liu¹, Junyao Song¹, Ziqi Xu¹, Xinghua Feng¹, Quan Jiang² and YaNan Zhao³, ¹Department of Rheumatology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China, ²Rheumatology Department, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China, ³Department of Rheumatology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, BeiJing, China
Background/Purpose: Th17 plays important role in pathogenesis of AS inflammation, and its main effector, IL-17, was the critical effector on mediating it. Activated of Th17…
Abstract Number: 2821 • 2015 ACR/ARHP Annual Meeting
Increased CD4 T Cell GM-CSF Production in Spondyloarthritis
M Hussein Al-Mossawi¹, Jelle De Wit², Anna Ridley³ and Paul Bowness¹, ¹Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, ²Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, ³Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, United Kingdom
Background/Purpose: Immunological, genetic and therapeutic studies have implicated the IL-17A/IL-23 inflammatory axis in SpA. GM-CSF is emerging as a cytokine that marks out a pathogenic…

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