Abstracts tagged "T cells and animal models"

Abstract Number: 2341 • 2012 ACR/ARHP Annual Meeting
Exacerbation of Collagen-Induced Arthritis by an Anti-CD3 Antibody Targeting Aminoterminal-Deficient CD3ε
María J. Pérez-Lorenzo¹, Elena Gonzalo², José M. Rojo³, María Galindo⁴, Jose L. Pablos⁴ and Gabriel Criado¹, ¹Grupo de Enfermedades Inflamatorias y Autoinmunes, Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, ²Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, ³Centro de Investigaciones Biológicas-CSIC, Madrid, Spain, ⁴Servicio de Reumatología, Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain
Background/Purpose: We have previously characterized naturally occurring forms of CD3e that lack the aminoterminal region (DNH2-CD3e) and are bound with high avidity by the YCD3-1…

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Abstracts tagged "T cells and animal models"

Exacerbation of Collagen-Induced Arthritis by an Anti-CD3 Antibody Targeting Aminoterminal-Deficient CD3ε