Abstracts tagged "systemic vasculitides and Biologic agents"

Abstract Number: 870 • 2019 ACR/ARP Annual Meeting
Off-Label Use of Biotherapies to Treat Relapsing And/or Refractory Eosinophilic Granulomatosis with Polyangiitis (Churg–Strauss)
Alice Canzian ¹, Nils Venhoff ², Silvia Sartorelli ³, Anne-Marie Ruppert ⁴, Matthieu Groh ⁵, Camille Taille ⁶, Virginie Rieu ⁷, Perrine Smets ⁷, François Maurier ⁸, Nicolas Girszyn ⁹, Maxime Samson ¹⁰, Claire de Moreuil ¹¹, Grégory Pugnet ¹², Xavier Delbrel ¹³, Jean-Emmanuel Kahn ¹⁴, Xavier Puéchal for the French Vasculitis Study Group ¹⁵, Giacomo Emmi ¹⁶, Loic Guillevin ¹⁵, Lorenzo Dagna ¹⁷, Jens Thiel ², Augusto Vaglio ¹⁸ and Benjamin Terrier¹⁵, ¹Cochin Hospital, Paris, France, ²Clinic for Rheumatology and Clinical Immunology, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany, ³Vita-Salute San Raffaele University, IRCCS San Raffaele Hospital, Milan, Italy, ⁴Tenon Hospital, Paris, France, ⁵Service de Médecine Interne, Centre de Référence des Syndromes Hyperéosinophiliques-CEREO, Hôpital Foch, Université Versailles–Saint-Quentin-en-Yvelines, Suresnes, France, Suresnes, France, ⁶Bichat Hospital, Paris, France, ⁷CHU, Clermont-Ferrand, France, ⁸Service de Médecine Interne, Hôpital Belle Isle, Metz, Metz, France, ⁹CHU, Rouen, France, ¹⁰Service de Médecine Interne et Immunologie Clinique, CHU Dijon Bourgogne, Hôpital François Mitterrand, Dijon ; Université Bourgogne-Franche Comté, INSERM, EFS BFC, UMR1098, F-21000 Dijon, Dijon, France, ¹¹CHU Brest, Brest, France, ¹²CHU de Toulouse, Hôpital Purpan, Service de Médecine Interne, Toulouse, France, ¹³CH, Pau, France, ¹⁴APHP, Boulogne Billancourt, France, ¹⁵National Referral Center for Rare Systemic Autoimmune Diseases Paris Cochin, Paris, France, ¹⁶Department of Experimental and Clinical Medicine, University of Firenze, Florence, Italy, Florence, Italy, ¹⁷Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy, ¹⁸Nephrology Unit, Parma University Hospital, Parma, Italy, Nephrology Unit, Parma University Hospital, Parma, Italy, Italy
Background/Purpose: Eosinophilic granulomatosis with polyangiitis (EGPA; formerly Churg–Strauss syndrome), is characterized by small-vessel necrotizing vasculitis, and blood and tissue eosinophilia in asthmatic individuals. Glucocorticoids (GCs)…

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