Abstracts tagged "systemic sclerosis and clinical trials"

Abstract Number: 1653 • 2019 ACR/ARP Annual Meeting
Efficacy and Safety of Romilkimab in Diffuse Cutaneous Systemic Sclerosis (dcSSc): A Randomized, Double-Blind, Placebo-Controlled, 24-week, Proof of Concept Study
Yannick Allanore¹, Christopher Denton ², Dinesh Khanna ³, Christina Soubrane ⁴, Corinne Esperet ⁴, Frederic Marrache ⁴, Raphael Bejuit ⁴, Amel Lahmar ⁵ and Peter Wung ⁵, ¹Dept. of Rheumatology A, Descartes University, APHP, Cochin Hospital, Paris, France, Paris, France, ²University College London Division of Medicine, Centre for Rheumatology and Connective Tissue Diseases, London, UK, London, United Kingdom, ³Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA, Ann Arbor, ⁴Sanofi, Chilly Mazarin, France, ⁵Sanofi, Bridgewater, NJ
Background/Purpose: Systemic sclerosis (SSc) is a progressive, multi-organ disease with limited treatment options. Interleukin-4 (IL-4) and IL-13 have been implicated in the general fibrotic pathway…