ACR Meeting Abstracts

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Abstracts tagged "Systemic lupus erythematosus (SLE)"

  • Abstract Number: 1268 • ACR Convergence 2025

    Development of the LupusCoach Chatbot: Results of a Focus Group

    Leila Khalili1, Pooja Desai2, Maya Souvignier2, Adrienne Pichon2, Stephen Suh3, Alberto Nordmann-Gomes2, Lena Mamykina2 and Anca Askanase1, 1Columbia University Medical Center, New York, NY, 2Columbia University Irving Medical Center, New York, NY, 3Columbia University Irving Medical Center, New York City, NY

    Background/Purpose: Self-management education and coaching are successful interventions for managing chronic health conditions. However, accessibility of in-person coaching is limited; digital coaching is available and…
  • Abstract Number: 1387 • ACR Convergence 2025

    Demographic and Clinical Characteristics of Patients Diagnosed With Sjögren’s Disease Using Electronic Health Records and Linked Claims Data From the US Excellence Network in RheumatoloGY (ENRGY) Practice-Based Research Network

    Jeffrey Curtis1, Emily Holladay2, Antton Egana3, Anjana Lalla3, Yujie Su4, Fenglong Xie5, Amy Mudano4, Shanette Daigle4 and Sara McCoy6, 1Foundation for Advancing Science, Technology, Education and Research, Birmingham, AL, 2University of Alabama at Birmingham, Edmond, OK, 3Novartis Pharmaceuticals Corporation, East Hanover, NJ, 4Foundation for Advancing Science, Technology, Education and Research (FASTER), Hoover, AL, 5The University of Alabama at Birmingham, Birmingham, AL, 6University of Wisconsin–Madison, Madison, WI

    Background/Purpose: Sjögren’s disease (SjD) is a chronic autoimmune disease characterized by systemic symptoms such as dryness, fatigue, musculoskeletal pain, and extraglandular manifestations. SjD may overlap…
  • Abstract Number: 1483 • ACR Convergence 2025

    Evidence of Early Cardiovascular Dysfunction in Young Systemic Lupus Erythematosus Patients Compared to Older Healthy Controls

    Fernanda M. Garcia-Garcia1, Oscar Azael Garza-Flores2, Esteban C. Garza-Gonzalez3, Rebeca L. Polina-Lugo4, Leslie Y. Lopez-Cantú1, Dionicio A. Galarza-Delgado1, Iris J. Colunga-Pedraza1, Jesus Alberto Cardenas-de la Garza5, Jose R Azpiri-Lopez6 and Victor M Fraga-Enriquez7, 1Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico, 2Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Guadalupe, Mexico, 3Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, San Nicolas de los Garza, Nuevo Leon, Mexico, 4Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico, 5Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Mexico, 6Cardiology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico, 7Cardiology Service, Hospital Universitario “Dr. Jose Eleuterio Gonzalez”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterized by systemic inflammation and accelerated atherosclerosis, leading to increased cardiovascular (CV) risk. While CV…
  • Abstract Number: 1500 • ACR Convergence 2025

    Prognostic Impact of Thrombocytopenia on Morbidity and Mortality in Systemic Lupus Erythematosus: A Retrospective Single-Center Study

    Milad Heydari-Kamjani1, Amir Daneshvar2, Dana Nachawati2, Elleson Harper2, Keri Ann Pfeil2, Meghan Gump2, Lindsay Frumker3 and Omer Pamuk1, 1University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH, 2University Hospitals Cleveland Medical Center/Case Western Reserve University, Cleveland, OH, 3University hospitals Cleveland medical center, Highland Heights, OH

    Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune rheumatic disease with heterogeneous hematologic manifestations. Thrombocytopenia (TP) in SLE may be associated with major organ involvement…
  • Abstract Number: 1516 • ACR Convergence 2025

    The Benefits of SGLT2i on GFR Slope and Proteinuria in SLE Depend on Subgroups of Diabetes Mellitus and Baseline eGFR

    Jennifer Lee1, Andrea Fava2, Daniel Goldman3, Laurence Magder4 and Michelle Petri3, 1Johns Hopkins University School of Medicine, Baltimore, MD, 2Johns Hopkins University, Baltimore, MD, 3Johns Hopkins University School of Medicine, Timonium, MD, 4University of Maryland, Baltimore, Baltimore, MD

    Background/Purpose: Lupus nephritis (LN) affects over 50% of SLE patients. Twenty percent of LN patients develop end-stage renal disease (ESRD) within 10 years. The 2021…
  • Abstract Number: 1534 • ACR Convergence 2025

    Rapid Oral Glucocorticoid Discontinuation or Dose Reduction Among US Patients with SLE Receiving Belimumab in a Real-World Setting

    Yan Chen1, Maral DerSarkissian1, Shumin Rui1, Justin Clark1, Daniel Moldaver2, Jeffrey J. Ellis3, Karen Worley3 and Aarat M Patel4, 1Analysis Group, Los Angeles, CA, 2GSK, Global Real-World Evidence & Health Outcomes Research, Toronto, ON, Canada, 3GSK, Global Real-World Evidence & Health Outcomes Research, Collegeville, PA, 4GSK, US Medical Affairs, Durham, NC

    Background/Purpose: Belimumab (BEL), a B-cell modulator mAb that selectively inhibits soluble B-lymphocyte stimulator and reduces autoreactive B cells that drive lupus disease activity, is approved…
  • Abstract Number: 1552 • ACR Convergence 2025

    Treatment With Anifrolumab Prevents Long-Term Cardiovascular Damage Accrual Compared With Real-World Standard of Care in Patients With Systemic Lupus Erythematosus: Findings From the LASER Study

    Zahi Touma1, Ian Bruce2, Richard Furie3, Eric Morand4, Raj Tummala5, Shelly Chandran6, Gabriel Abreu7, Jacob Knagenhjelm7, Cathy Emmas8, Lyra Agustin8, Alessandra Venerus9, Tarana Mehdikhanova10, Zheyuan Yang10 and Miina Waratani8, 1University of Toronto, Toronto, ON, Canada, 2Centre for Public Health, Faculty of Medicine, Health and Life Sciences, Queen's University, Belfast, Manchester, United Kingdom, 3Division of Rheumatology, Northwell Health, Great Neck, NY, 4Centre for Inflammatory Diseases, Monash University and Monash Health, Melbourne, Victoria, Australia, 5AstraZeneca, BioPharmaceuticals R&D, Gaithersburg, Gaithersburg, MD, 6AstraZeneca, Medical & Scientific Affairs, R&I, Mississauga, ON, Canada, 7AstraZeneca, BioPharmaceuticals R&D, Gothenburg, Sweden, 8AstraZeneca, BioPharmaceuticals Medical, Cambridge, United Kingdom, 9IQVIA, EMEA Real World Methods and Evidence Generation, Milan, Italy, 10IQVIA, EMEA Real World Methods and Evidence Generation, London, United Kingdom

    Background/Purpose: Patients with systemic lupus erythematosus (SLE) can develop cardiovascular (CV) damage (angina, myocardial infarction, ventricular dysfunction, valvular disease, or pericarditis for 6 months/pericardiectomy) particularly…
  • Abstract Number: 1707 • ACR Convergence 2025

    Racial and Ethnic Disparities in Kidney Transplant Outcomes Among Patients With Systemic Lupus Erythematosus (SLE): A 20-Year Analysis Spanning Before and After the 2014 Kidney Allocation System Revision

    Soziema Salia1, Boniface Mensah2, Ufuoma Mamoh1, Gilava Hedayati1, Terrylyna Baffoe-Bonnie3, Joan Morny4 and Christhopher Haas3, 1MedStar Health Georgetown University (Baltimore) Internal Medicine Program, Baltimore, MD, 2MedStar Health Georgetown University (Baltimore) Internal Medicine Program, Baltimore, CA, 3MedStar Health Georgetown University (Baltimore) Internal Medicine Program, Baltimore, 4Piedmont Athens Regional Internal Medicine Residency Program, Athens, GA

    Background/Purpose: Systemic lupus erythematosus (SLE) is a leading cause of end-stage kidney disease (ESKD) in young women, particularly among racial and ethnic minorities. Kidney transplantation…
  • Abstract Number: 1777 • ACR Convergence 2025

    Granzyme B as a regulator of interferon alpha production in cutaneous lupus erythematosus

    Touraj Khosravi1, Ahmed Eldaboush2, Darae Kang3 and Victoria Werth2, 1Department of Dermatology, Perelman Shool of Medicine, University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3University of Pennsylvania, Potomac, MD

    Background/Purpose: Recent studies have shown that monocytes, macrophages, and conventional DCs, but not plasmacytoid dendritic cells (pDC), are major sources of IFNα in cutaneous lupus…
  • Abstract Number: 1845 • ACR Convergence 2025

    Immune Cell Profiles and Transcriptomic Signatures of Atherosclerosis in Systemic Lupus Erythemathosus

    Rodolfo Martinez-Canales1, Andres M. Ortiz-Rios2, Braulio R. Avalos-Garcia2, Eva Abigaid Galindo-Calvillo2, Mario Cesar Salinas-Carmona1, Noe Macias-Segura1, Lorena Perez-Barbosa2, Dionicio A. Galarza-Delgado3 and Cassandra Michele Skinner-Taylor2, 1Immunology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Nuevo Leon, Mexico, 2Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Nuevo Leon, Mexico, 3Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico

    Background/Purpose: Systemic lupus erythematosus (SLE) significantly increases the risk of premature atherosclerosis, contributing to long-term morbidity and mortality. Traditional cardiovascular risk factors do not fully…
  • Abstract Number: 1916 • ACR Convergence 2025

    Adherence to cervical cancer screening programs in women with Systemic Lupus Erythematosus

    Carmen Lasa Teja1, Carolina Aguirre-Portilla2, Virginia Portilla González3, Carmen Bejerano-Herreria2, Alfonso Corrales-Martínez4 and Ricardo Blanco5, 1Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain., Riotuerto, Cantabria, Spain, 2Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander , Spain, Santander, Spain, 3Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander , Spain, Santander, 4Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, Santander, Spain, 5Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, Santander, Cantabria, Spain

    Background/Purpose: Women with Systemic Lupus Erythematosus (SLE) are at a higher risk of persistent HPV infection and developing premalignant cervical lesions and cervical cancer. High-risk…
  • Abstract Number: 2199 • ACR Convergence 2025

    Disparities in Reproductive Health Counseling Among Hispanic Women with Autoimmune Rheumatic Diseases: Insights from a Patient-Reported Survey in an Urban Safety-Net Setting

    Eaman Alhassan1, Laura Kobashigawa2, Vanessa Ramos2, Jack Rodman2 and Leanna Wise3, 1University of Pittsburgh Medical Center, Pittsburgh, PA, 2University of Southern California, Los Angeles, 3LAGMC/Keck Medicine of USC, Los Angeles

    Background/Purpose: Reproductive-age Hispanic women with rheumatoid arthritis, juvenile idiopathic arthritis (combined, inflammatory arthritis; IA), and systemic lupus erythematosus (SLE) often bear a higher disease burden…
  • Abstract Number: 2377 • ACR Convergence 2025

    Statin Use for Primary Prevention of Atherosclerotic Cardiovascular Disease Among Patients with Systemic Lupus Erythematosus

    Aakash V. Patel1, Lingxiao Zhang2, Emily S. Lau3, Hyon K. Choi4 and April Jorge5, 1Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2Massachusetts General Hospital, Boston, 3Massachusetts General Hospital, Harvard Medical School, Boston, 4MASSACHUSETTS GENERAL HOSPITAL, Lexington, MA, 5Massachusetts General Hospital, Boston, MA

    Background/Purpose: Cardiovascular disease (CVD) is the most common cause of mortality among patients with systemic lupus erythematosus (SLE). Statin medications play a crucial role for…
  • Abstract Number: 2393 • ACR Convergence 2025

    Improving Clinical Outcomes In SLE Arthritis Trials: Post-Hoc Analysis Of A Prospective Intervention Study

    Samuel Wood1, Khaled Mahmoud2, Md Yuzaiful Md Yusof2, Philip Conaghan2, Elizabeth Hensor2 and Ed Vital3, 1University of Leeds, Leeds Institute for Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom, 2University of Leeds, Leeds, United Kingdom, 3University of Leeds, Leeds, England, United Kingdom

    Background/Purpose: Musculoskeletal (MSK) manifestations of SLE are the most frequently assessed domain in clinical trials. Optimal MSK assessment is contested; candidates include the binary or…
  • Abstract Number: 2411 • ACR Convergence 2025

    The 2019 EULAR/ACR and 2012 SLICC Classification Criteria for SLE Should Be Applied with Caution as Diagnostic Criteria

    Luca Mazzoleni1, Francesca Crisafulli2, Md Yuzaiful Md Yusof3, Aamir Aslam4, Andrew Barr5, Lesley-Anne Bissell6, Shouvik Dass5, Jack E Arnold7, Ed Vital8, Franco Franceschini9 and Porntip Intapiboon10, 1University of Brescia, Brescia, Italy, 2ASST Spedali Civili and University of Brescia, Brescia, Italy, 3University of Leeds, Leeds, United Kingdom, 4Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 5Leeds teaching hospitals- NHS trust, Leeds, United Kingdom, 6Leeds Teaching Hospitals NHS Trust, Leeds, England, United Kingdom, 7Leeds Institute of Rheumatic & Musculoskeletal Medicine, Leeds, United Kingdom, 8University of Leeds, Leeds, England, United Kingdom, 9University of Brescia, Brescia, Brescia, Italy, 10Prince Of Songkla universitiy, Tambon Kohong, Thailand

    Background/Purpose: To assess the 2012 SLICC and 2019 EULAR/ACR classification criteria performance as diagnostic criteria in two cohorts of ANA-positive patients clinically suspected of having…
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All abstracts accepted to PRYSM are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 6:00 PM CT on March 18. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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