Abstract Number: 1459 • 2016 ACR/ARHP Annual Meeting
Enhanced Efficacy of Early Vs. Late IL-1β Antagonism in Murine Arthritis Mediated By Deficiency of the IL-1 Receptor Antagonist IL-1ra
Background/Purpose: IL-1 blockade is highly effective for systemic juvenile idiopathic arthritis (sJIA), but clinical observations raise the possibility that initiation of treatment in a “window…