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Abstracts tagged "synovium and ultrasound"

  • Abstract Number: 3098 • 2015 ACR/ARHP Annual Meeting

    Synovial Lymphocytic Aggregates Associate with Highly Active RA and Predict Erosive Disease at 12 Months: Results from the Pathobiology of Early Arthritis Cohort

    Maria DiCicco1, Frances Humby1, Stephen Kelly2, Rebecca Hands1, nora ng3, Arti Mahto3, Illias Lazarou3, Vidalba Rocher1, Lu Zou3, Michele Bombardieri4, Christopher Buckley5, A.H.M. van der Helm- van Mil6, Robert B.M. Landewé7, Désirée van der Heijde8, Iain B. McInnes9, Peter C. Taylor10 and Costantino Pitzalis11, 1Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom, 2William Harvey Research Institute, Centre for Experimental Medicine and Rheumatology, Queen Mary University of London, London, United Kingdom, 3William Harvey Research Institute, Centre for Experimental Medicine and Rheumatology, London, United Kingdom, 4Experimental Medicine and Rheumatology, Queen Mary University of London, London, United Kingdom, 5University of Birmingham, Rheumatology Research Group, Birmingham, United Kingdom, 6Leiden University Medical Center, Leiden, Netherlands, 7University of Amsterdam and Atrium Medical Center, Amsterdam, Netherlands, 8Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 9Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom, 10Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford Botnar Research Centre, Oxford, United Kingdom, 11Centre for Experimental Medicine & Rheumatology, Queen Mary's School of Medicine and Dentistry, London, United Kingdom

    Background/Purpose: The inflammatory cell infiltrate in RA synovium has been recognised to organise into lymphocytic aggregates (Ags) with data to suggest that these structures are…
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