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Abstracts tagged "synovitis and ultrasound"

  • Abstract Number: 1363 • 2018 ACR/ARHP Annual Meeting

    Progression of Pain, Stiffness, Function Changes, and Ultrasound Detected Synovitis and Osteophyte Formation in Patients with Hand Osteoarthritis over Three Years

    Olga Sleglova1, Olga Ruzickova2, Karel Pavelka1 and Ladislav Šenolt1, 1Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, 2Institute of Rheumatology, Prague, Czech Republic, Prague, Czech Republic

    Background/Purpose: Hand osteoarthritis (HOA) is a common and frequent cause of pain. HOA is a heterogeneous group of disorders with two main subsets including non-erosive…
  • Abstract Number: 2906 • 2018 ACR/ARHP Annual Meeting

    Synovitis Focused Ultrasound in Rheumatoid Arthritis: A Joint Reduction Strategy

    Daniel Kuo1, Gurjit Kaeley2, Ami Ben-Artzi3, Jenny Brook4, Astrid Floegel-Shetty4, David Elashoff4 and Veena K. Ranganath1, 1Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, 2Rheumatology, University of Florida College of Medicine, Jacksonville, Jacksonville, FL, 3Rheumatology, Cedars Sinai Medical Center, Beverly Hills, CA, 4Department of Medicine Statistics Core, UCLA David Geffen School of Medicine, Los Angeles, CA

    Background/Purpose: Musculoskeletal ultrasound is increasingly being used as a tool to assess inflammatory burden in rheumatoid arthritis (RA). Ultrasound-based outcome measures include power Doppler (PD)…
  • Abstract Number: 241 • 2017 ACR/ARHP Annual Meeting

    Histological and Clinical Correlates of Ultrasound Measures of Joint Inflammation: Analysis of RA Tissue Obtained By Ultrasound Guided Biopsy in Phase 1 of the Accelerating Medicines Partnership RA Network

    Andrew Filer1, Arthur M. Mandelin II2, Edward F. DiCarlo3, Brendan Boyce4, Darren Tabechian5, Ralf G. Thiele6, Stephan Kelly7, Ellen M. Gravallese8, Diane Horowitz9, Kevin Wei10, Deepak Rao11, Vivian P. Bykerk12 and Jennifer H. Anolik13, 1Institute of Inflammation and Ageing (IIA), University of Birmingham, Birmingham, United Kingdom, 2Rheumatology, Northwestern University, Chicago, IL, 3Laboratory Medicine, Hospital for Special Surgery, New York, NY, 4University of Rochester Medical Center, Rochester, NY, 5Medicine, Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, 6Medicine, University of Rochester Medical Center, Rochester, NY, 7Queen Mary University of London, London, United Kingdom, 8Lazare Research Bldg, University of Massachusetts Medical School, Worcester, MA, 9Division of Rheumatology, North Shore - Long Island Jewish Health System, Woodbury, NY, 10Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 11Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Spring, IN, 122-005, Mt Sinai Hospital, Toronto, ON, Canada, 13Medicine- Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY

    Background/Purpose: The AMP-RA network applies cutting edge technologies to the study of tissue obtained by ultrasound guided synovial biopsy from patients with rheumatoid arthritis (RA).…
  • Abstract Number: 2210 • 2017 ACR/ARHP Annual Meeting

    Thumb Base Osteoarthritis: Associations between Pain and Synovitis on Ultrasound

    F.P.B. Kroon1, S. Ermurat2, M. Kortekaas1, M. Reijnierse3 and M. Kloppenburg1,4, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Rheumatology, Uludag University Medical Faculty, Bursa, Turkey, 3Radiology, Leiden University Medical Center, Leiden, Netherlands, 4Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Osteoarthritis (OA) in the first carpometacarpal (CMC1) joint in the thumb base is frequent and has a large contribution in hand pain and disability.…
  • Abstract Number: 134 • 2016 ACR/ARHP Annual Meeting

    Synovitis Assessed By the German 7-Joint Ultrasound Score (US7S) Is Associated with the Reversible Activity-Related Component of Physical Disability in Patients with Rheumatoid Arthritis 

    Jakub Zavada1, Petra Hanova1, Jana Hurnakova1, Lenka Szczukova2, Michal Uher2, Šárka Forejtová1, Martin Klein1, Heřman F Mann1, Marta Olejarova1, Olga Sleglova1, Olga Ruzickova1 and Karel Pavelka1, 1Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, 2Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Brno, Czech Republic

    Background/Purpose: Restoring normal functioning is a major therapeutic aim. Differences in the sources of functional limitations should be considered in the interpretation of functional measures.…
  • Abstract Number: 136 • 2016 ACR/ARHP Annual Meeting

    The 7-Joints Musculoskeletal Ultrasound Score (US7 score) Predicts Therapeutic Change in Patients with Early Rheumatoid Arthritis

    Sarah Ohrndorf1, Philipp Daniel Oberdorfer2, Lien Le3, Ulrich Mansmann3, Lisa Ines Sprenger2, Thomas Häupl4, Sandra Hermann2, Gabriela Schmittat2, Silvia Pade2, GR Burmester5, Anne-Marie Glimm2 and Marina Backhaus6, 1Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Berlin, Germany, 2Department of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany, 3Institut für medizinische Informationsverarbeitung, Biometrie und Epidemiologie, Ludwig-Maximilians-Universität Munich, Munich, Germany, 4Department of Rheumatology and Clinical Immunology, Charité University Medicine, Berlin, Germany, 5Charité – University Medicine Berlin, Berlin, Germany, 6Department of Rheumatology & Immunology, University Medicine Charit, Berlin, Germany

    Background/Purpose: Treatment decisions in patients with Rheumatoid Arthritis (RA) after the “Treat to Target (T2T)” - principle is widely recommended, as this management strategy leads…
  • Abstract Number: 142 • 2016 ACR/ARHP Annual Meeting

    Quality Assessment of Ultrasound Guided Synovial Biopsies Performed in Clinical Practice

    Aurélie Najm1, Marie-Françoise Heymann2, Géraldine Bart1, Yves Maugars1 and Benoît Le Goff1, 1Rheumatology, Nantes University Hospital, Nantes, France, 2Histopathology, Histopathology, Nantes University Hospital, Nantes, France

    Background/Purpose: Synovial tissue is the principal target and end organ involved in the pathogenesis of multiple articular disease processes. Histological and bacteriological analyses of synovial…
  • Abstract Number: 153 • 2016 ACR/ARHP Annual Meeting

    Synovial Immunophenotype and Ultrasonography: A Contemporaneous Study of Different Compartments of the Knee Joint

    Aurélie Najm1,2, Carl Orr3, Benoît Le Goff MD PhD1, Ursula Fearon4 and Douglas J. Veale5, 1Rheumatology, Nantes University Hospital, Nantes, France, 2Rheumatology, Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, University College Dublin, Dublin, Ireland, 3Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, University College Dublin, Dublin 4, Ireland, 4Trinity College Dublin, Department of Molecular Rheumatology, Trinity College Dublin, Dublin, Ireland, 5Consultant Rheumatologist, Centre for Arthritis and Rheumatic Disease, St. Vincent’s University Hospital and University College Dublin, Dublin 4, Ireland

    Background/Purpose: Histological analysis of synovial tissue, despite being a reliable and accurate assessment for synovitis, is not routinely performed. Ultrasonography (US) is a fast, available…
  • Abstract Number: 543 • 2016 ACR/ARHP Annual Meeting

    Synovial Features of Rheumatoid Arthritis and Psoriatic Arthritis Differ in Patients in Clinical and Ultrasound Remission after Anti-TNF Therapy

    Stefano Alivernini1, Luca Petricca1, Laura Bui2, Barbara Tolusso1, Gabriele Di Sante1, Roberta Benvenuto2, Anna Laura Fedele1, Elisa Gremese1 and Gianfranco Ferraccioli1, 1Division of Rheumatology - Institute of Rheumatology and Affine Sciences, Catholic University of the Sacred Heart, Rome, Italy, 2Division of Histopathology - Institute of Pathology, Catholic University of the Sacred Heart, Rome, Italy

    Background/Purpose:  Persistent disease remission is the major goal of Rheumatoid Arthritis (RA) and Psoriatic Arthritis (PsA) treatment. The combined use of clinical and ultrasound selection…
  • Abstract Number: 151 • 2015 ACR/ARHP Annual Meeting

    Residual Synovitis in Ultrasound (US) Is Associated with an Evolution Towards Rheumatoid Arthritis  (RA) in Patients with Inflammatory Polyarthralgia without ANTI-Citrulinated Antibodies (ACPA)

    Pascal Zufferey1,2,3, Claudia Rebell Jr.4, Alexandre Dumusc5, Mauro lucini4, Juerg Hains6, Alexander K. So Sr.7 and Charles Benaim8, 1Rheumatology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland, 2Pierer Decler, Chuv, Lausanne, Switzerland, 3Rhu /Dal .Chuv, Rheumatology, Lausanne, Switzerland, 4DAL, RHU/CHUV, lausanne, Switzerland, 5RHU/CHUV, lausanne, Switzerland, 6DAL, RHU/CHUV, Lausanne, Syria, 7Service De Rhumatologie, CHUV, Lausanne, Switzerland, 8DAL, MPR, Lausanne, Switzerland

    Background/Purpose: In ACPA positive patients, subclinical synovitis as observed by US has been demonstrated in pre RA patients and seems to be predictive for future…
  • Abstract Number: 163 • 2015 ACR/ARHP Annual Meeting

    Ultrasonographic Assessment Covers Clinical Examination in the Localization of Ankle Pathology in Rheumatoid Arthritis

    Yukihiro Toyota1, Kaoru Minegishi-Takase1, Maasa Hama1, Ryusuke Yoshimi1, Yumiko Sugiyama1, Naomi Tsuchida1, Yosuke Kunishita1, Daiga Kishimoto1, Reikou Kamiyama1, Yohei Kirino1, Mitsuhiro Takeno1,2, Atsuhisa Ueda1 and Yoshiaki Ishigatsubo1,3, 1Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan, 2Department of Allergy and Rheumatology, Nippon Medical School, Tokyo, Japan, 3Yokosuka Rheumatic Diseases Center, Yokosuka City Hospital, Yokosuka, Japan

    Background/Purpose: Though rheumatoid arthritis (RA) commonly affects ankle joints, ankle joints are not included in widely used composite measures of disease activity with 28-joint counts.…
  • Abstract Number: 185 • 2015 ACR/ARHP Annual Meeting

    Success Rate and Utility of Ultrasound Guided Synovial Biopsies in Clinical Practice

    Aurélie Najm, Benoît Le Goff and Yves Maugars, Rheumatology, Rheumatology, Nantes, France

    Background/Purpose: Histological and bacteriological analysis of synovial tissue (ST) can be useful in the diagnosis of arthritis of undetermined origin. Ultrasound can assist this biopsy…
  • Abstract Number: 137 • 2014 ACR/ARHP Annual Meeting

    Evaluation of Metalloproteinase-3 As a Soluble Biomarker of Synovitis Using Weighted Joint Counts Assessed Clinically and on Ultrasound Imaging

    Agata Burska1,2, Elizabeth Hensor2,3, Jackie L. Nam3, Lukasz Kozera4, Richard J. Wakefield3, Paul Emery3 and Ann W Morgan5, 1NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds., Leeds, United Kingdom, 2joint first authorship, Leeds, United Kingdom, 3NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 4Faculty of Pharmacy and Laboratory Diagnostics, Wroclaw Medical University, Wroclaw, Poland, Wroclaw, Poland, 5NIHR-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom

    Background/Purpose: Synovial inflammation is known to play a central role in articular cartilage degradation in rheumatoid arthritis (RA); it could be a passive marker of…
  • Abstract Number: 131 • 2014 ACR/ARHP Annual Meeting

    Detection of Synovitis and Erosions with an Automated Ultrasound System: Data from a Prospective Cohort with Early and Established RA

    Matthias Witt1, Janette Frielinghausen2, Jan Leipe2, Hendrik Schulze-Koops2, Ruediger Mueller3 and Mathias Grunke2, 1Division of Rheumatology and Clinical Immunology, University of Munich, Munich, Germany, 2Division for Rheumatology, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany, 3Rheumatology, Kantonspital St. Gallen, St. Gallen, Switzerland

    Background/Purpose: Arthrosonography has proven to be a sensitive and reliable, but time-consuming method for the evaluation of arthritis in small joints of patients with RA…
  • Abstract Number: 129 • 2014 ACR/ARHP Annual Meeting

    Seven Joints Ultrasound Scoring System May be Useful and Effective in Assessing Disease Activity in Patients with Rheumatoid Arthritis in the State of Remission in Daily Clinical Practice

    Petra Hanova1, Jakub Zavada1, Jana Hurnakova1, Martin Klein1, Olga Sleglova1, Marta Olejarova1, Martin Komarc2, Ladislav ŠEnolt1 and Karel Pavelka3, 1Institute of Rheumatology, Charles University, 1st Medical Faculty, Prague, Czech Republic, 2Institute of Biophysics and Informatics, Prague, Czech Republic, 3Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic

    Background/Purpose: To evaluate if the 7-joint ultrasound scoring system (US7) is able to find synovitis in patients in remission of RA.   Methods: Patients with rheumatoid…
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