Abstracts tagged "synovitis and tumor necrosis factor (TNF)"

Abstract Number: 1131 • 2012 ACR/ARHP Annual Meeting
Intraarticular Infliximab for Knee Osteoarthritis: High Baseline Levels of Synovial Cellularity and High MRI Cartilage Injury At the Lateral Tibial Plateau Predict Improvement in Total WOMAC Score
Jeremy R. Schue¹, Ossama Tawfik², Rebecca Bolce³, Donald D. Smith¹, Gary Hinson⁴, Jo A. Wick⁵ and Herbert B. Lindsley⁶, ¹Internal Medicine, Kansas University Med Ctr, Kansas City, KS, ²Pathology, Kansas University Med Ctr, Kansas City, KS, ³Crescendo Bioscience Inc., South San Francisco, CA, ⁴Radiology, Kansas University Med Ctr, Kansas City, KS, ⁵Biostatistics, Kansas University Med Ctr, Kansas City, KS, ⁶Medicine, Kansas University Med Ctr, Kansas City, KS
Background/Purpose: Synovial tissue from patients with OA often demonstrates inflammation. We hypothesized that a single intraarticular (IA) injection of an anti-TNF drug would decrease inflammatory…

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Abstracts tagged "synovitis and tumor necrosis factor (TNF)"

Intraarticular Infliximab for Knee Osteoarthritis: High Baseline Levels of Synovial Cellularity and High MRI Cartilage Injury At the Lateral Tibial Plateau Predict Improvement in Total WOMAC Score