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Abstracts tagged "synovial fluid and WNT Signaling"

  • Abstract Number: 816 • ACR/ARP Annual Meeting 2019

    The Long Non-coding RNA HOTAIR Regulates BMP2 and Wnt Pathways in Synovial Fibroblasts

    Muriel Elhai1, Raphael Micheroli 1, Mojca Frank-Bertoncelj 2, Kerstin Klein 1, Oliver Distler 3 and Caroline Ospelt 2, 1Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Switzerland., Zürich, Switzerland, 2University Hospital Zürich, Zürich, Switzerland, 3Dept. of Rheumatology, University Hospital Zürich, Zürich, Switzerland, Zürich, Switzerland

    Background/Purpose: Mechanisms involved in joint patterning of rheumatic diseases remain unknown. The long non-coding RNA HOTAIR is exclusively expressed in synovial fibroblasts (SF) from lower…

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