Abstracts tagged "synovial fluid and synovium"

Abstract Number: 995 • 2015 ACR/ARHP Annual Meeting
In Rheumatoid Arthritis Only a Few Expanded T-Cell Clones Dominate in Joint Inflammation: A Study in Seven RA Patients Undergoing Paired Synovial Tissue Biopsies in Multiple Joints
Anne Musters¹, Paul L. Klarenbeek^1,2, Marieke E. Doorenspleet^1,2, Rebecca E.E. Esveldt^1,2, Barbera D.C. van Schaik³, Sander W. Tas^1,2, Antoine H.C. van Kampen³, Frank Baas⁴ and Niek de Vries^1,2, ¹Dept. of Clinical Immunology & Rheumatology, Amsterdam Rheumatology and immunology Center | Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ²Dept. of Experimental Immunology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ³Bioinformatics Laboratory, Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ⁴Dept. of Genome Analysis, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands
Background/Purpose: Previously we found a strong enrichment of highly expanded T-cell clones in rheumatoid arthritis (RA) synovial tissue of inflamed joints. To gain more insight…

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