Abstracts tagged "switched memory B-cells"

Abstract Number: 1022 • 2019 ACR/ARP Annual Meeting
Single Cell Transcriptome Analysis of Circulating Plasmacytoid Dendritic Cells and Switched Memory B-cells in SLE Patients Reveals Transcriptional Subsets Within the Classical Cell Lineages
Amrutesh Puranik¹, Yogita Ghodke-Puranik ², Regine Tipon ², Mark Jensen ¹, Auroni Gupta ³, Jacqueline Paredes ³, Uma Sankaramanchi ⁴, Ilona Nln ³, Amit Saxena ⁵, H. Michael Belmont ⁶, Peter Izmirly ⁷, Robert Clancy ⁷, Jill Buyon ⁵ and Timothy Niewold ², ¹Colton Center for Autoimmunity, NYU School of Medicine, New York, NY, ²Colton Center for Autoimmunity, NYU School of Medicine, New York, ³Colton Center for Autoimmunity, NYU School of Medicine, ny, ⁴Colton Center for Autoimmunity, NYU Langone Medical Center, NY, ⁵New York University School of Medicine, New York, NY, ⁶New York University School of Medicine, Ney York, ⁷New York University School of Medicine, New York
Background/Purpose: Both plasmacytoid dendritic cells (pDCs) and switched memory B cells (SMBCs) are considered to be key effector cells in systemic lupus erythematosus. It seems…