Abstracts tagged "Subclinical Cardiovascular Disease"

Abstract Number: 1007 • ACR Convergence 2021
Vascular Deposition of Oxidized LDL Is Increased in Children with Untreated Juvenile Dermatomyositis
Jacob Spitznagle¹, Akadia Kacha-Ochana², Joan Cook-Mills³, Amer Khojah², Gabrielle Morgan⁴ and Lauren Pachman⁵, ¹Hospital for Special Surgery, New York, NY, ²Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, ³Indiana University School of Medicine, Departments of Pediatrics and Microbiology & Immunology, Indianapolis, IN, ⁴Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Northwestern's Feinberg School of Medicine. Ann and Robert H. Lurie Children's Hospital of Chicago; Stanley Manne Children's Research Institute of Chicago, Lake Forest, IL
Background/Purpose: Juvenile dermatomyositis (JDM) is a systemic vasculopathy associated with metabolic derangements and possible increased risk for premature atherosclerosis. Oxidation of low-density lipoprotein (LDL) in…
Abstract Number: 1357 • ACR Convergence 2021
Clinical and Molecular Profiles Determining Cardiovascular Risk in Psoriatic Arthritis: Specific Response to Apremilast and Methotrexate
Nuria Barbarroja¹, Iván Arias de la Rosa¹, Cristobal Román-Rodriguez², Ignacio Gomez-Garcia³, Clementina López Medina⁴, M.Lourdes Ladehesa-Pineda⁵, Carlos Pérez-Sánchez⁶, Maria del Carmen Ábalos-Aguilera², Alejandra Patiño-Trives⁷, Isabel Añón-Oñate⁸, Maria Jose Pérez-Galán⁸, Rocio Guzmán-Ruiz², Maria del Mar Malagón², Chary Lopez-Pedrera², alejandro Escudero², Eduardo Collantes-Estevez² and Maria Dolores López-Montilla², ¹University of Cordoba/IMIBIC/Reina Sofia Hospital, Cordoba, Spain, ²IMIBIC/Reina Sofia Hospital/University of Córdoba, Córdoba, Spain, ³Rheumatology Department, Reina Sofia University Hospital. Cordoba (Spain) / University of Cordoba (Spain) / Maimonides Institute for Biomedical Research (IMIBIC). Cordoba (Spain) / Physical Medicine and Rehabilitation Department. Infanta Margarita Hospital. Cabra (Spain), Córdoba, Spain, ⁴Department of Rheumatology, Reina Sofia Hospital, IMIBIC, University of Cordoba, Cordoba, Spain/ Department of Rheumatology, University of Paris, Cochin Hospital, Paris, France, ⁵Hospital Universitario Reina Sofía, Córdoba, Spain, ⁶IMIBIC, Córdoba, Spain, ⁷Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, ⁸Rheumatology department, University Hospital of Jaen, Jaen, Spain
Background/Purpose: 1) to evaluate clinical and subclinical markers of cardiovascular (CV) disease risk and its relationship with inflammation, disease activity and metabolic comorbidities in PsA…
Abstract Number: 1368 • ACR Convergence 2021
Characterising Exercise Capacity in Systemic Sclerosis Using Cardiac Magnetic Resonance Imaging, Skeletal Muscle Imaging and Cardiopulmonary Exercise Testing
Laura Ross¹, Benedict Costello², Dylan Hansen³, Anniina Lindqvist², Zoe Brown⁴, Andrew Burns⁴, David Prior⁴, Wendy Stevens⁴, Marcus Pianta⁴, Warren Perera⁴, Andre La Gerche² and Mandana Nikpour¹, ¹University of Melbourne at St Vincent's Hospital, Melbourne, Australia, ²Baker Heart and Diabetes Institute, Melbourne, Australia, ³St. Vincent’s Hospital Melbourne, Victoria, Australia, Adelaide, Australia, ⁴St Vincent's Hospital, Melbourne, Australia
Background/Purpose: Impaired exercise capacity contributes to functional impairment, negatively impacting individuals’ quality of life. Functional impairment is notable from early in the disease course of…
Abstract Number: 1929 • ACR Convergence 2021
Metabolomics Identifies Early Mechanisms of Atherogenic Dyslipidaemia in Juvenile-SLE Patients Associated with Inflammation
George Robinson¹, Kirsty Waddington¹, Junjie Peng¹, Anna Radziszewska¹, David Isenberg², Yiannis Ioannou¹, Ines Pineda-Torra¹, Coziana Ciurtin¹ and Elizabeth Jury¹, ¹University College London, London, United Kingdom, ²Centre for Rheumatology, University College London, London, United Kingdom
Background/Purpose: Cardiovascular disease (CVD) is a leading cause of mortality in patients with juvenile-onset systemic lupus erythematosus (JSLE) through atherosclerosis, the build-up of lipids and…
Abstract Number: 0191 • ACR Convergence 2020
Increased Frequency of Lower Limb Arterial Obstruction in Rheumatoid Arthritis
Ahmed Oglah¹, Ali Hussein², Jose Felix Restrepo³, Carlos Lorenzo³, Agustin Escalante³ and Inmaculada Del Rincon³, ¹University of Texas Health Science Center at San Antonio/ Internal Medicine Residency program, San Antonio, TX, ²University of Texas Health Science Center at San Antonio/ Department of Internal Medicine/ Rheumatology, San Antonio, TX, ³University of Texas Health Science Center at San Antonio/ Department of Medicine/ Rheumatology, San Antonio, TX
Background/Purpose: Despite a high frequency of cardiovascular disease in rheumatoid arthritis (RA), peripheral arterial disease in RA has received little attention. The objective of the…
Abstract Number: 1330 • ACR Convergence 2020
Subclinical atherosclertoic disease in ankylosing spondylitis and non-radiographic axial spondyloarthritis. A multicenter study with 806 patients.
Inigo Gonzalez-Mazon¹, Javier Rueda-Gotor², Ivan Ferraz-Amaro³, Lara Sanchez-Bilbao⁴, David Martinez-Lopez⁵, Fernanda Genre⁶, Natalia Palmou Fontana⁷, Vanesa Calvo-Río², Sara Remuzgo-Martínez⁶, Veronica Pulito-Cueto⁶, Alfonso Corrales⁸, Leticia Lera-Gómez⁶, Virginia Portilla⁶, Cristina Mata⁹, Vanesa Hernández-Hernández¹⁰, Santos Castañeda¹¹, Esther Francisca Vicente-Rabaneda¹², C Fernandez-Carballido¹³, M Paz Martínez-Vidal¹⁴, David Castro-Corredor¹⁵, Joaquín Anino-Fernández¹⁵, Juan Carlos Quevedo-Abeledo¹⁶, Carlos Rodríguez-Lozano¹⁷, María Luz García Vivar,¹⁸, Eva Galínez-Agirregoikoa¹⁸, C. Fernandez-Diaz¹⁹, Javier Llorca²⁰, Raquel López-Mejías⁶, Esther Montes-Perez²¹, Diana Peiteado²², Chamaida Plasencia²³, Alejandro Balsa-Criado²⁴, Nuria Barbarroja²⁵, Lourdes Ladehesa-Pineda²⁶, Rafaela Ortega-Castro²⁷, Eduardo Collantes-Estévez²⁶, Ricardo Blanco²⁸ and Miguel Ángel González-Gay²⁹, ¹Hospital Universitario Marques de Valdecilla, Bezana, Spain, ²H.U. Marques de Valdecilla, Santander, Spain, ³Division of Rheumatology. Hospital Universitario de Canarias. Spain., Santa Cruz de Tenerife, Spain, ⁴Hospital Universitario Marques de Valdecilla, Santander, Spain, ⁵Hospital Universitario Marques de Valdecilla, Santander (SPAIN), Spain, ⁶Research group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic bone Diseases of the Musculoskeletal System, IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain, ⁷UNIVERSITARY HOSPITAL MARQUES VALDECILLA, Santander, Spain, ⁸Research group on genetic epidemiology and atherosclerosis in systemic diseases and in metabolic bone diseases of the musculoskeletal system, IDIVAL; and Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, ⁹Hospital de Laredo, Santander, Spain, ¹⁰Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, ¹¹Princesa University Hospital, Universidad Autónoma, Madrid, Madrid, Spain, ¹²Hospital Universitario de la Princesa, IIS-Princesa, UAM, Madrid, Madrid, Spain, ¹³H San Juan, Alicante, Spain, ¹⁴Hospital General Universitario de Alicante, Alicante, Spain, ¹⁵Hospital General Universitario de Ciudad Real, Ciudad Real, Spain, ¹⁶Hospital Dr. Negrín, Las Palmas de Gran Canaria, Spain, ¹⁷Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain, ¹⁸Hospital Universitario Basurto, Bilbao, Spain, ¹⁹H. Marqués de Valdecilla, Madrid, Spain, ²⁰School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), Santander, Spain, ²¹Diagnóstico Médico Cantabria (DMC), Santander, Spain, ²²Hospital Universitario La Paz-IdiPaz, Madrid, Spain, ²³Rheumatology, La Paz University Hospital-IdiPAZ, madrid, Spain, ²⁴HOSPITAL UNIVERSITARIO LA PAZ, madrid, Spain, ²⁵Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Cordoba, Spain, ²⁶Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Córdoba, Spain, ²⁷Hospital Universitario Reina Sofía, Córdoba, Spain, ²⁸Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain, ²⁹Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain
Background/Purpose: Cardiovascular (CV) mortality and morbidity is increased in ankylosing spondylitits (AS) as compared to the general population. Carotid plaque, considered as a surrogate marker…

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