ACR Meeting Abstracts

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Abstracts tagged "Spondyloarthropathies"

  • Abstract Number: 0399 • ACR Convergence 2022

    ASAS Recommendations for Requesting and Reporting Imaging in Patients with Suspected Axial Spondyloarthritis

    Torsten Diekhoff1, Iris Eshed2, Chiara Giraudo3, Hildrun Haibel4, Kay-Geert Hermann5, Manouk de Hooge6, Lennart Jans7, Anne Jurik8, Robert G Lambert9, Pedro Machado10, Walter P Maksymowych11, Michael Mallinson12, Helena Marzo-Ortega13, Victoria Navarro-Compán14, Susanne Pedersen15, Mikkel Østergaard16, Monique Reijnierse17, Martin Rudwaleit18, Fernando Andres Sommerfleck19, Ulrich Weber20, Xenofon Baraliakos21 and Denis Poddubnyy22, 1Charité – Universitätsmedizin Berlin, Berlin, Germany, 2Sheba Medical Center, Tel Aviv, Israel, 3University of Padova, Padova, Italy, 4Charité - Universitätsmedizin, Berlin, Berlin, Germany, 5Charité - Universitätsmedizin Berlin, Berlin, Germany, 6Ghent University Hospital, Luxembourg, Luxembourg, 7Ghent University Hospital, Ghent, Belgium, 8Aarhus University Hospital, Aarhus, Denmark, 9University of Alberta, Edmonton, AB, Canada, 10University College London, London, United Kingdom, 11Department of Medicine, University of Alberta, Edmonton, AB, Canada, 12ASIF Axial Spondyloarthritis International Federation, London, United Kingdom, 13Leeds Teaching Hospitals Trust and University of Leeds, Leeds, United Kingdom, 14Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, 15Rigshospitalet, København, Denmark, 16Rigshospitalet, University of Copenhagen, Glostrup, Denmark, 17Leiden University Medical Center, Leiden, Netherlands, 18University of Bielefeld, Klinikum Bielefeld, Bielefeld; Germany Klinikum Bielefeld and Charité Berlin, Germany, and Gent University, Gent, Belgium, 19Sanatorio Julio Mendez, Buenos Aires, Argentina, 20Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, 21Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 22Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany

    Background/Purpose: Clinicians face uncertainties in their daily practice when requesting imaging for patients with suspicion of axial spondyloarthritis (axSpA) or producing a report because requirements…
  • Abstract Number: 1029 • ACR Convergence 2022

    Virtual Assessment in Axial Spondyloarthritis: Validation of Video Observation of Spinal Metrology

    Laura Passalent1, Sareh Keshavarzi1, Robert Inman1 and Nigil Haroon2, 1University Health Network, Toronto, ON, Canada, 2Schroeder Arthritis Institute, University Health Network; University of Toronto, Toronto, ON, Canada

    Background/Purpose: A shift to virtual clinical encounters was required because of the COVID-19 pandemic. To date, there have been few studies exploring the utility of…
  • Abstract Number: 1515 • ACR Convergence 2022

    Assessing the Difference Between Radiographic Axial Spondylorthritis and Non-radiographic Axial Spondylorthritis in a Two-center Descriptive Study with Mexican Patients: The Influence of Clinical, Demographic, Laboratory and Clinimetric Features

    John Londono1, Gustavo Rodriguez-Salas2, Igor Rueda-Cardenas3, Ana Maria Santos1, Marta Mantilla1, Juan Camilo Santacruz2, Cesar Pachecho4, Gilberto Vargas-Alarcon5 and Ruben Burgos vargas6, 1Spondyloarthropathies study group - Universidad de La Sabana - Hospital Militar Central, Bogotá, Colombia, 2Spondyloathropathies study group Universidad de La Sabana Hospital Militar Central, Bogotá, Colombia, 3Spondyloarthropathies study group - Universidad de LA Sabana - Hospital Militar Central, Colombia, Colombia, 4Universidad Autónoma de chihuahua, Chihuahua, Mexico, 5Insituto Nacional de Cardiología Ignacio Chavez, Ciudad de México, Mexico, 6hospital general de mexico, Ciudad de México, Mexico

    Background/Purpose: Spondyloarthritis (SpA) is a group of inflammatory rheumatic diseases that have some key features in common. According to ASAS, this condition is classified into…
  • Abstract Number: 2257 • ACR Convergence 2022

    MRI Spinal Lesions in Patients Without MRI or Radiographic Lesions in the Sacroiliac Joints Typical of Axial Spondyloarthritis

    Walter P Maksymowych1, Mikkel Østergaard2, Xenofon Baraliakos3, Pedro Machado4, Susanne J. Pedersen5, Ulrich Weber6, Iris Eshed7, Manouk de Hooge8, Joachim Sieper9, Denis Poddubnyy10, Martin Rudwaleit11, Désirée van der Heijde12, Robert Landewé13 and Robert G Lambert14, 1Department of Medicine, University of Alberta, Edmonton, AB, Canada, 2Rigshospitalet, University of Copenhagen, Glostrup, Denmark, 3Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 4University College London, London, United Kingdom, 5Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, 6Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, 7Sheba Medical Center, Tel Aviv, Israel, 8Ghent University Hospital, Luxembourg, Luxembourg, 9Charité - Universitätsmedizin, Berlin, Berlin, Germany, 10Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany, 11University of Bielefeld, Klinikum Bielefeld, Bielefeld; Germany Klinikum Bielefeld and Charité Berlin, Germany, and Gent University, Gent, Belgium, 12Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, 13Amsterdam University Medical Center, Meerssen, Netherlands, 14University of Alberta, Edmonton, AB, Canada

    Background/Purpose: There is limited data as to the frequency of spinal lesions on MRI in patients without MRI or radiographic features typical of sacroiliac joint…
  • Abstract Number: 0405 • ACR Convergence 2022

    Efficacy and Safety of Tofacitinib in Patients with Ankylosing Spondylitis by Baseline BMI: A Post Hoc Analysis of Phase 2 and Phase 3 Trials

    Hillary Norton1, Paula Sliwinska-Stanczyk2, Tomas Hala3, Bassel Elzorkany4, Lori Stockert5, Harry Shi5, Cunshan Wang6, Jerome Paulissen7 and Christopher Ritchlin8, 1Sante Fe Rheumatology, Santa Fe, NM, 2Reumatika Centrum Reumatologii, Warsaw, Poland, 3Center for Clinical and Basic Research, Pardubice, Czech Republic, 4Department of Rheumatology, Cairo University, Cairo, Egypt, 5Pfizer, Inc, Collegeville, PA, 6Pfizer Inc, Groton, CT, 7Pfizer Inc, New York, NY, 8Allergy, Immunology and Rheumatology Division, University of Rochester Medical School, Canandaigua, NY

    Background/Purpose: Higher BMI is associated with reduced response to TNF inhibitors (TNFi) in patients (pts) with AS.1 Tofacitinib is an oral Janus kinase inhibitor for…
  • Abstract Number: 1031 • ACR Convergence 2022

    Foot Involvement in Psoriatic Arthritis- a Retrospective Study

    Sofia Ferreira Azevedo1, Carolina Mazeda2, Susana P. Silva3, Claudia P. Oliveira1 and Anabela Barcelos3, 1Rheumatology Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal, 2Centro Hospitalar Baixo Vouga, Ovar, Portugal, 3Centro Hospitalar Baixo Vouga, Aveiro, Portugal

    Background/Purpose: Foot involvement is well recognized in many inflammatory rheumatic diseases, namely in Spondylarthritis (SpA), where its early recognition is of utmost importance. Psoriatic arthritis…
  • Abstract Number: 1516 • ACR Convergence 2022

    How Disease Activity Can Affect Workability in Spondyloarthropaties: A Monocentric Cohort Analysis

    Federico Fattorini1, Cosimo Cigolini2, Gabriele Marchetti3, Andrea Delle Sedie4, Linda Carli5 and Marta Mosca5, 1Rheumatology Unit, University of Pisa, Pisa, Italy, 2Rheumatology Unit, University of Pisa, Pisa, Toscana, Italy, 3University of Pisa, Pisa, Toscana, Italy, 4University of Pisa, Pisa, Pisa, Italy, 5Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, PISA, Italy

    Background/Purpose: Spondyloarthropathies (SpA) may compromise the working ability (WA) of patients, often affected by the disease during their productive life. The Work Productivity and Activity…
  • Abstract Number: 2258 • ACR Convergence 2022

    Relative Frequencies of the Spectrum of MRI Lesions in the Sacroiliac Joints of Healthy Individuals and Patients with Non-Specific Back Pain: What Is the Impact of Increasing Age?

    Ulrich Weber1, Susanne Pedersen2, Mikkel Østergaard3, Pedro Machado4, Xenofon Baraliakos5, Robert G Lambert6 and Walter P Maksymowych7, 1Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, 2Rigshospitalet, København, Denmark, 3Rigshospitalet, University of Copenhagen, Glostrup, Denmark, 4University College London, London, United Kingdom, 5Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 6University of Alberta, Edmonton, AB, Canada, 7Department of Medicine, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: Previous studies of patients with axial spondyloarthritis (axSpA) have demonstrated that certain MRI structural lesions in the sacroiliac joints (SIJ), notably erosions, has high…
  • Abstract Number: 0406 • ACR Convergence 2022

    Are the BASDAI & BASFI Capturing the Full Impact of Disease Activity on Quality of Life in Women with Axial Spondyloarthritis?

    Sinead Maguire1, Fiona Wilson2, Phil Gallagher3 and Finbar (Barry) O'Shea1, 1St James' Hospital, Dublin, Ireland, 2Trinity College Dublin, Dublin, Ireland, 3St Vincent's University Hospital, Dublin, Ireland

    Background/Purpose: The tools to assess disease activity and quality of life in axial spondyloarthritis (axSpA) were developed in ankylosing spondylitis cohorts biased towards inclusion of…
  • Abstract Number: 1032 • ACR Convergence 2022

    Anti-arthritogenic Effect of Smoking in Curdlan-Administered SKG Mice

    YoungEun Kim1, Eun-Ju Lee1, Jae-Hyun Lee1, Soo Min Ahn1, Ji Seon Oh2, Seokchan Hong1, Chang Keun Lee1, Bin Yoo1 and Yong Gil Kim1, 1Department of Rheumatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, Seoul, Republic of Korea, 2Department of Information Medicine, Big Data Research Center, Asan Medical Center, Seoul, Republic of Korea

    Background/Purpose: Alpha7 nicotinic acetylcholine receptor (α7nAChR), a member of AChR expressed in various immune cells and synoviocytes, has an important role in the anti-inflammatory pathway…
  • Abstract Number: 1601 • ACR Convergence 2022

    Female Psoriatic Arthritis Patients Show Differences in Treatment Response to IL12/23 Inhibition in Combination with or Without MTX Compared to Male – Results from a Multicenter Investigator-initiated Randomized Placebo-controlled Clinical Trial

    Michaela Koehm1, Ann Christina Foldenauer2, Tanja Rossmanith3, Herbert Kellner4, Uta Kiltz5, Juergen Rech6, Gerd Burmester7, David Kofler8, Jan Brandt-Juergens9, Stephanie Finzel10, Raoul Bergner11, Maren Sieburg12 and Frank Behrens13, 1Rheumatology Goethe-University Frankfurt, Frankfurt Am Main, Germany, 2Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt, 3Fraunhofer Institute for Translational Medicine & Pharmacology ITMP, Frankfurt, Germany, 4Schwerpunktpraxis für Rheumatologie und Gastroenterologie, Munich, Germany, 5Rheumazentrum Ruhrgebiet, Herne, Germany, 6University Clinic Erlangen, Erlangen, Germany, 7Charité University Medicine Berlin, Berlin, Germany, 8University of Cologne, Cologne, Germany, 9Rheumatologische Schwerpunktpraxis, Berlin, Germany, 10University of Freiburg, Freiburg, Germany, 11Klinikum Ludwigshafen, Ludwigshafen, Germany, 12Rheumatologische Facharztpraxis, Magdeburg, Germany, 13Rheumatology University Hospital & Fraunhofer Institute Translational Medicine and Pharmacology, Goethe-University Frankfurt, Frankfurt Am Main, Germany

    Background/Purpose: Subgroup analysis from different clinical trials and real-world data suggest, that there are differences in baseline characteristics, clinical phenotypes, and treatment responses in female…
  • Abstract Number: 0413 • ACR Convergence 2022

    Efficacy and Safety of Non-Pharmacological and Non-Biological Therapy: A Systematic Literature Review Informing the 2022 Update of the ASAS-EULAR Recommendations for the Management of Axial Spondyloarthritis

    Augusta Ortolan1, Casper Webers2, Alexandre Sepriano3, Louise Falzon4, Xenofon Baraliakos5, Robert Landewé6, Sofia Ramiro7, Désirée van der Heijde8 and Elena Nikiphorou9, 1University of Padova/Leiden University Medical Center, Padova, Italy, 2Maastricht University Medical Centre, Maastricht, Netherlands, 3Leiden University Medical Centre, Portela Loures, Portugal, 4Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, Sheffield, United Kingdom, 5Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 6Amsterdam University Medical Center, Meerssen, Netherlands, 7Leiden University Medical Center, Leiden, Netherlands, 8Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, 9Leiden University Medical Center & King's College London, London, United Kingdom

    Background/Purpose: Since the 2016 recommendations for axial spondyloarthritis (axSpA) management, new evidence emerged regarding axSpA treatment. The aim of this work was to update the…
  • Abstract Number: 1033 • ACR Convergence 2022

    Risk of Mood Disorders in SpA Patients and Correlations with Disease Activity, Quality of Life and Working Ability: Analysis of a Monocentric Cohort

    Cosimo Cigolini1, Federico Fattorini1, Linda Carli2, Andrea Delle Sedie3, Marta Mosca2 and Gabriele Marchetti4, 1Rheumatology Unit, University of Pisa, Pisa, Toscana, Italy, 2Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, PISA, Italy, 3University of Pisa, Pisa, Pisa, Italy, 4University of Pisa, Pisa, Toscana, Italy

    Background/Purpose: Spondyloarthropathies (SpA) are chronic inflammatory arthritides, characterized by both peripheral and axial skeletal involvement and some typical extra-articular marks; they tend to associate with…
  • Abstract Number: 1612 • ACR Convergence 2022

    Prediction of Psoriatic Arthritis Tool (PRESTO): Development and Performance of a New Scoring System for Psoriatic Arthritis Risk

    Lihi Eder1, Ker-Ai Lee2, Vinod Chandran3, Jessica Widdifield4, Aaron Drucker4, Christopher Ritchlin5, Cheryl F Rosen4, Richard Cook2 and Dafna Gladman6, 1Women’s College Research Institute, Department of Medicine, University of Toronto, Toronto, ON, Canada, 2University of Waterloo, Waterloo, ON, Canada, 3Departments of Medicine and Laboratory Medicine and Pathobiology, University of Toronto/ Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, ON, Canada, 4University of Toronto, Toronto, ON, Canada, 5Allergy, Immunology and Rheumatology Division, University of Rochester Medical School, Canandaigua, NY, 6Toronto Western Hospital, Schroeder Arthritis Institute, Toronto, ON, Canada

    Background/Purpose: A simple, scalable tool that identifies psoriasis patients at high risk for developing PsA could improve early detection and facilitate early intervention. Our overall…
  • Abstract Number: 0416 • ACR Convergence 2022

    Efficacy and Safety of Biological DMARDs: A Systematic Literature Review Informing the 2022 Update of the ASAS-EULAR Recommendations for the Management of Axial Spondyloarthritis

    Casper Webers1, Augusta Ortolan2, Alexandre Sepriano3, Louise Falzon4, Xenofon Baraliakos5, Robert Landewé6, Sofia Ramiro7, Désirée van der Heijde8 and Elena Nikiphorou9, 1Maastricht University Medical Centre, Maastricht, Netherlands, 2University of Padova/Leiden University Medical Center, Padova, Italy, 3Leiden University Medical Centre, Portela Loures, Portugal, 4Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, Sheffield, United Kingdom, 5Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 6Amsterdam University Medical Center, Meerssen, Netherlands, 7Leiden University Medical Center, Leiden, Netherlands, 8Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, 9Leiden University Medical Center & King's College London, London, United Kingdom

    Background/Purpose: Since the 2016 update of the management recommendations for axial spondyloarthritis (axSpA), new evidence has emerged on the efficacy and safety of biological disease-modifying…
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