Abstracts tagged "Spondyloarthropathies"

Abstract Number: 0386 • ACR Convergence 2022
Quantitative Proteomic Screening Uncovers Diagnostic and Monitoring Serum Biomarkers of Ankylosing Spondylitis
Mark Hwang¹, Jessica Castillo², kamala Vanarsa², Jim Zheng³, Shervin Assassi⁴, Chandra Mohan² and John Reveille⁵, ¹McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, ²University of Houston, Houston, TX, ³UTHealth School of Bioinformatics, Houston, TX, ⁴McGovern Medical School, University of Texas, Houston, TX, ⁵University of Texas McGovern Medical School, Houston, TX
Background/Purpose: We sought to discover novel serum biomarkers of ankylosing spondylitis (AS) for diagnosis and monitoring disease activity. Methods: We used biologic-treatment naïve AS and…
Abstract Number: 1022 • ACR Convergence 2022
Validation of the SPARCCRETIC E-Tool for Ensuring Scoring Proficiency of MRI Lesions in Axial Spondyloarthritis
Walter P Maksymowych¹, Anna Hadsbjerg², Mikkel Østergaard³, Raphael Micheroli⁴, Susanne J. Pedersen⁵, Adrian Ciurea⁶, Nora Vladimirova², Michael Nissen⁷, Kristyna Bubova⁸, Stephanie Wichuk⁹, Manouk de Hooge¹⁰, Ashish J Mathew¹¹, Karlo Pintaric¹², Monika gregova¹³, Ziga Snoj¹², Marie Wetterslev¹⁴, Karel Gorican¹⁵, Joel Paschke¹⁶, Iris Eshed¹⁷ and Robert G Lambert⁹, ¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ²Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ³Rigshospitalet, University of Copenhagen, Glostrup, Denmark, ⁴University Hospital Zurich, Department of Rheumatology, Zürich, Switzerland, ⁵Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, ⁶University Hospital Zurich, Zürich, Switzerland, ⁷Hopitaux Universitaires de Genève, Geneva, Switzerland, ⁸First Faculty of Medicine, Charles University,, Prague, Czech Republic, ⁹University of Alberta, Edmonton, AB, Canada, ¹⁰Ghent University Hospital, Luxembourg, Luxembourg, ¹¹Rigshospitalet, Copenhagen, Denmark, ¹²Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia, ¹³Institue of Rheumatology, Prague, ¹⁴Rigshospitalet, Copenhagen, Glostrup, Denmark, ¹⁵MSK radiology unit, Radiology section – Diagnostic department, Geneva University Hospitals, Geneva, Switzerland, ¹⁶CARE Arthritis LTD, Edmonton, AB, Canada, ¹⁷Sheba Medical Center, Tel Aviv, Israel
Background/Purpose: Quantification of inflammatory and structural lesions in the sacroiliac joints (SIJ) on MRI scans from patients with axial spondyloarthritis (axSpA) has a growing list…
Abstract Number: 1503 • ACR Convergence 2022
Is Inflammation-driven Bone Loss Associated with Two-year Bone Formation at the Same Vertebra in Axial Spondyloarthritis? – a Multilevel MRI and Low Dose CT Analysis from the Sensitive Imaging of Axial Spondyloarthritis (SIAS) Cohort
Mary Lucy Marques¹, Nuno Pereira da Silva², Désirée van der Heijde³, Rosalinde Stal⁴, Xenofon Baraliakos⁵, Juergen Braun⁶, Monique Reijnierse⁴, Caroline Bastiaenen⁷, Sofia Ramiro⁴ and floris van Gaalen⁴, ¹Leiden University Medical Center, Coimbra, Portugal, ²Radiology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, ³Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, ⁴Leiden University Medical Center, Leiden, Netherlands, ⁵Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ⁶Rheumazentrum Ruhrgebiet, Herne, Germany, ⁷Department of Epidemiology, Maastricht University, Maastricht, Netherlands
Background/Purpose: In radiographic axial spondyloarthritis (r-axSpA), inflammation-driven trabecular bone loss is hypothesised to trigger bone repair at an anatomically distinct site of the same vertebra…
Abstract Number: 2199 • ACR Convergence 2022
Primary Non-adherence to Biologics and Immunomodulatory Therapies for Rheumatoid Arthritis, Psoriatic Arthritis, and Spondyloarthritis Using Linked EHR and Pharmacy Claims Data
Jeffrey Curtis¹, Yujie Su², Cassie Clinton², Patrick Stewart³, Bryant England⁴, Tim Buekelman⁵ and Fenglong Xie², ¹Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham, AL, ³Bendcare, Boca Raton, FL, ⁴University of Nebraska Medical Center, Omaha, NE, ⁵FASTER, Hoover, AL
Background/Purpose: Many patients with autoimmune and inflammatory conditions discontinue biologics and other immunomodulatory medications prematurely, but many fail to even start (primary non-adherence). We examined…
Abstract Number: 0387 • ACR Convergence 2022
Sleep Quality in Patients with Psoriatic Arthritis and Its Relationship with Activity and Comorbidity
Marta Ibañez Martinez¹, Sonia Pastor Navarro², Olga Compán Fernández², Belén Miguel Ibáñez², Ana Isabel Turrión Nieves², Susana Gómez Castro¹, Olga Martínez González², Cristina Hidalgo Calleja², Esther Toledano Martinez³ and Carlos Montilla Morales², ¹Hospital Universitario Salamanca, Salamanca, Spain, ²Hospital Universitario de Salamanca, Salamanca, Spain, ³Hospital Clínico San Carlos, Madrid, Spain
Background/Purpose: To evaluate the quality of sleep in patients with psoriatic arthritis (PsA) and its relationship with/to clinical variables, activity, functionality, the impact of the…
Abstract Number: 1023 • ACR Convergence 2022
Are We Treating-to-target in Spondyloarthritis (SpA)? A Cross Sectional Analysis from the Asia Pacific League of Associations for Rheumatology (APLAR) SpA Registry
Isaac Cheng¹, Ying Ying Leung², Ho SO¹, Praveena Chiowchanwisawakit³, Stanley Angkodjojo⁴, Muhammad Saeed⁵, Kichul Shin⁶, Han Joo Baek⁷, Mohit Goyal⁸, Muhammad Haroon⁹, Eman Satti¹⁰, Nallasivan Subramanian¹¹, Fariz Yahya¹², Soosan Soroosh¹³, ASAL ADNAN RIDHA¹⁴, Ho Yin Chung¹⁵, James Cheng-Chung WEI¹⁶, Kishimoto Mitsumasa¹⁷ and Lai-shan Tam¹, ¹The Chinese University of Hong Kong, Hong Kong, China, ²Rheumatology Department, Singapore General Hospital, Singapore, Singapore, ³Mahidol University, Bangkok, Thailand, ⁴Sengkang General Hospital / Singhealth, Singapore, Singapore, ⁵Central Park Medical College, Lahore, Pakistan, ⁶Seoul Metropolitan Government- Seoul National University Boramae Medical Center, Seoul, Republic of Korea, ⁷Gachon University College of Medicine, Inchon, Republic of Korea, ⁸CARE Pain & Arthritis Centre, Udaipur, India, ⁹Doctor, Tralee, Ireland, ¹⁰Hamad Medical Corporation, Doha, Qatar, ¹¹Velammal Medical College Hospital, Velammal, India, ¹²University of Malaya, Kuala Lumpur, Malaysia, ¹³Army University for Medical School, Tehran, Iran, ¹⁴Baghdad Teaching Hospital, Baghdad, Iraq, ¹⁵Chiron Medical, Hong Kong, Hong Kong, ¹⁶Chung Shan Medical University Hospital, Taichung, Taiwan, ¹⁷Department of Nephrology and Rheumatology, Kyorin University School of Medicine, Tokyo, Japan
Background/Purpose: Data on the extent to which internationally agreed treat-to-target (T2T) recommendations were applied in clinical practice in patients with SpA across the Asia-Pacific region…
Abstract Number: 1510 • ACR Convergence 2022
Modifying Lifestyle Factors May Offer the Potential to Enhance the Outcome of Tumour Necrosis Factor Inhibitors in Axial Spondyloarthritis – Data from 14 European Countries
Gareth Jones¹, Ovidiu Rotariu¹, Brigitte Michelsen², Bente Glintborg³, Bjorn Gudbjornsson⁴, Arni Geirsson⁵, Heikki Relas⁶, Pia Isomäki⁷, Jakub Závada⁸, Karel Pavelka⁹, Ziga Rotar¹⁰, Matija Tomsic¹⁰, Michael Nissen¹¹, Adrian Ciurea¹², Catalin Codreanu¹³, Johan Karlsson Wallman¹⁴, Eirik Kristianslund¹⁵, Simon Rasmussen¹⁶, Lykke Ørnbjerg¹⁷, Maria José Santos¹⁸, Mikkel Østergaard¹⁹, Merete L Hetland²⁰ and Gary Macfarlane¹, ¹University of Aberdeen, Aberdeen, Scotland, United Kingdom, ²Center for treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, Kristiansand, Norway, ³Rigshospitalet, Glostrup, Virum, Denmark, ⁴Centre for Rheumatology Research, University Hospital, Reykjavik, Iceland, ⁵Department of Rheumatology, Landspitali University Hospital, Reykjavik, Iceland, ⁶Rheumatology, Inflammation Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland, ⁷Centre for Rheumatology, Tampere University Hospital, Tampere, Finland, ⁸Institute of Rheumatology, Prague, Czech Republic, ⁹Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Praha, Czech Republic, ¹⁰University Medical Centre Ljubljana, Ljubljana, Slovenia, ¹¹Hopitaux Universitaires de Genève, Geneva, Switzerland, ¹²University Hospital Zurich, Zürich, Switzerland, ¹³Center for Rheumatic Diseases, Bucharest, Romania, ¹⁴Lund University and Skane University Hospital, Hjarup, Sweden, ¹⁵Diakonhjemmet Hospital, Division of Rheumatology and Research, Oslo, Norway, ¹⁶Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, ¹⁷Copenhagen Center for Arthritis Research, Glostrup, Denmark, ¹⁸Hospital Garcia de Orta, Almada, Charneca da Caparica, Portugal, ¹⁹Rigshospitalet, University of Copenhagen, Glostrup, Denmark, ²⁰Rigshospitalet, Glostrup, Denmark
Background/Purpose: In axial spondyloarthritis (axSpA) much attention has been focused on pharmacological management, including tumour necrosis factor inhibitors (TNFi), as a means to reducing inflammation,…
Abstract Number: 2206 • ACR Convergence 2022
Understanding Inter-rater Variability in Scoring of Entheseal Lesions: Results from the Diagnostic Ultrasound Enthesitis Tool (DUET) Study
Lihi Eder¹, Fangya Ma², Josefina Marin³, Minna Kohler⁴, Janeth Yinh⁵, Ari Polachek⁶, Marcos Rosemffet⁷, Ernesto Rodriguez⁸, Ilaria Tinnazzi⁹, Amir Haddad¹⁰, Philippe Carron¹¹, Mariana Alves Ferreira Martins¹², Catherine Bakewell¹³, Fahmeen J. Afgani¹⁴, Richard Cook², Sibel Aydin¹⁵ and Gurjit S. Kaeley¹⁶, ¹Women’s College Research Institute, Department of Medicine, University of Toronto, Toronto, ON, Canada, ²University of Waterloo, Waterloo, ON, Canada, ³Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁴Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁵Massachusetts General Hospital, Boston, MA, ⁶Tel Aviv Medical Center, Tel Aviv, Israel, ⁷Rheumatology Unit, Instituto de Rehabilitación Psicofísica, Capital Federal, Argentina, ⁸Florida Medical Clinic, Tampa, FL, ⁹Ospedale Sacro Cuore-Don Calabria, Negrar, Italy, ¹⁰Carmel Medical Centre, Haifa, Israel, ¹¹Ghent University Hospital, Ghent, Belgium, ¹²São José Do Rio Preto Medical School, São José do Rio Preto, Brazil, ¹³Intermountain Healthcare, Salt Lake City, UT, ¹⁴Women's College Hospital, Toronto, ON, Canada, ¹⁵University of Ottawa, Rheumatology, Ottawa, Canada, Ottawa, ON, Canada, ¹⁶UF COM-J, Ponte Vedra Beach, FL
Background/Purpose: Variability in scoring of sonographic entheseal lesions may be influenced by patient characteristics and sonographer expertise. We aimed to assess inter-rater agreement in scoring…
Abstract Number: 0389 • ACR Convergence 2022
Vaccine Effectiveness Among Patients with Psoriatic Disease: A Population-based Study
Lihi Eder¹, Idit Lavi², Amir Haddad³, Nili Stein⁴, Ilan feldhamer⁵, ARNON DOV COHEN⁵, Walid Saliba² and Devy Zisman², ¹Women’s College Research Institute, Department of Medicine, University of Toronto, Toronto, ON, Canada, ²Carmel Medical Center, Haifa, Israel, ³Carmel Medical Centre, Haifa, Israel, ⁴Department of Community Medicine and Epidemiology, Carmel Medical Center, Haifa, Israel, ⁵Clalit Health Services, Tel Aviv, Israel
Background/Purpose: We assess the effectiveness of COVID-19 vaccination in preventing SARS-CoV2 infection and COVID-19 hospitalizations in patients with psoriatic disease (PsD) and non-psoriatic controls, and…
Abstract Number: 1027 • ACR Convergence 2022
Low Dose Computed Tomography Hounsfield Units: A Reliable Methodology for Assessing Changes in Vertebral Bone Density in Radiographic Axial Spondyloarthritis
Mary Lucy Marques¹, Nuno Pereira da Silva², Désirée van der Heijde³, Monique Reijnierse⁴, Juergen Braun⁵, Xenofon Baraliakos⁶, floris van Gaalen⁴ and Sofia Ramiro⁴, ¹Leiden University Medical Center, Coimbra, Portugal, ²Radiology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, ³Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, ⁴Leiden University Medical Center, Leiden, Netherlands, ⁵Rheumazentrum Ruhrgebiet, Herne, Germany, ⁶Rheumazentrum Ruhrgebiet Herne, Herne, Germany
Background/Purpose: In radiographic axial Spondyloarthritis (r-axSpA), low dose Computed Tomography (ldCT) Hounsfield Units (HU) were shown to cross-sectionally reliably assess bone density at each vertebra…
Abstract Number: 1514 • ACR Convergence 2022
Self-referral Strategy for Early Diagnosis of Axial Spondyloarthritis- Preliminary Analysis from Finding Axial Spondyloarthritis Study
Abhijeet Danve, Yale University, New Haven, CT
Background/Purpose: Lack of timely rheumatology referral for suspected axial spondyloarthritis (axSpA) is a major contributor to delayed diagnosis in patients with chronic back pain (CBP).…
Abstract Number: 2254 • ACR Convergence 2022
Detection of Active Inflammatory and Structural Changes Indicative of Axial Spondyloarthritis on MRI of Sacroiliac Joint Using a Deep Learning Framework
Keno Kyrill Bressem¹, Lisa Adams¹, Fabian Proft², Kay-Geert Hermann³, Torsten Diekhoff¹, Laura Spiller¹, Stefan Niehues¹, Marcus Makowski⁴, Bernd Hamm¹, Mikhail Protopopov⁵, valeria Rios-Rodriguez⁶, Hildrun Haibel⁷, Judith Rademacher⁵, Murat Torgutalp⁷, Robert G Lambert⁸, Xenofon Baraliakos⁹, Walter P Maksymowych¹⁰, Janis Vahldiek¹ and Denis Poddubnyy², ¹Charité – Universitätsmedizin Berlin, Berlin, Germany, ²Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany, ³Charité - Universitätsmedizin Berlin, Berlin, Germany, ⁴Technical University of Munich, Munich, Germany, ⁵Charité Universitätsmedizin Berlin, Berlin, Germany, ⁶Charité-Universitätsmedizin Berlin, Berlin, Germany, ⁷Charité - Universitätsmedizin, Berlin, Berlin, Germany, ⁸University of Alberta, Edmonton, AB, Canada, ⁹Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ¹⁰Department of Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Magnetic resonance tomography (MRI) plays a key role in the early diagnosis of axial spondyloarthritis (axSpA). However, the detection of changes indicative of axSpA…
Abstract Number: 0399 • ACR Convergence 2022
ASAS Recommendations for Requesting and Reporting Imaging in Patients with Suspected Axial Spondyloarthritis
Torsten Diekhoff¹, Iris Eshed², Chiara Giraudo³, Hildrun Haibel⁴, Kay-Geert Hermann⁵, Manouk de Hooge⁶, Lennart Jans⁷, Anne Jurik⁸, Robert G Lambert⁹, Pedro Machado¹⁰, Walter P Maksymowych¹¹, Michael Mallinson¹², Helena Marzo-Ortega¹³, Victoria Navarro-Compán¹⁴, Susanne Pedersen¹⁵, Mikkel Østergaard¹⁶, Monique Reijnierse¹⁷, Martin Rudwaleit¹⁸, Fernando Andres Sommerfleck¹⁹, Ulrich Weber²⁰, Xenofon Baraliakos²¹ and Denis Poddubnyy²², ¹Charité – Universitätsmedizin Berlin, Berlin, Germany, ²Sheba Medical Center, Tel Aviv, Israel, ³University of Padova, Padova, Italy, ⁴Charité - Universitätsmedizin, Berlin, Berlin, Germany, ⁵Charité - Universitätsmedizin Berlin, Berlin, Germany, ⁶Ghent University Hospital, Luxembourg, Luxembourg, ⁷Ghent University Hospital, Ghent, Belgium, ⁸Aarhus University Hospital, Aarhus, Denmark, ⁹University of Alberta, Edmonton, AB, Canada, ¹⁰University College London, London, United Kingdom, ¹¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ¹²ASIF Axial Spondyloarthritis International Federation, London, United Kingdom, ¹³Leeds Teaching Hospitals Trust and University of Leeds, Leeds, United Kingdom, ¹⁴Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, ¹⁵Rigshospitalet, København, Denmark, ¹⁶Rigshospitalet, University of Copenhagen, Glostrup, Denmark, ¹⁷Leiden University Medical Center, Leiden, Netherlands, ¹⁸University of Bielefeld, Klinikum Bielefeld, Bielefeld; Germany Klinikum Bielefeld and Charité Berlin, Germany, and Gent University, Gent, Belgium, ¹⁹Sanatorio Julio Mendez, Buenos Aires, Argentina, ²⁰Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, ²¹Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ²²Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany
Background/Purpose: Clinicians face uncertainties in their daily practice when requesting imaging for patients with suspicion of axial spondyloarthritis (axSpA) or producing a report because requirements…
Abstract Number: 1029 • ACR Convergence 2022
Virtual Assessment in Axial Spondyloarthritis: Validation of Video Observation of Spinal Metrology
Laura Passalent¹, Sareh Keshavarzi¹, Robert Inman¹ and Nigil Haroon², ¹University Health Network, Toronto, ON, Canada, ²Schroeder Arthritis Institute, University Health Network; University of Toronto, Toronto, ON, Canada
Background/Purpose: A shift to virtual clinical encounters was required because of the COVID-19 pandemic. To date, there have been few studies exploring the utility of…
Abstract Number: 1515 • ACR Convergence 2022
Assessing the Difference Between Radiographic Axial Spondylorthritis and Non-radiographic Axial Spondylorthritis in a Two-center Descriptive Study with Mexican Patients: The Influence of Clinical, Demographic, Laboratory and Clinimetric Features
John Londono¹, Gustavo Rodriguez-Salas², Igor Rueda-Cardenas³, Ana Maria Santos¹, Marta Mantilla¹, Juan Camilo Santacruz², Cesar Pachecho⁴, Gilberto Vargas-Alarcon⁵ and Ruben Burgos vargas⁶, ¹Spondyloarthropathies study group - Universidad de La Sabana - Hospital Militar Central, Bogotá, Colombia, ²Spondyloathropathies study group Universidad de La Sabana Hospital Militar Central, Bogotá, Colombia, ³Spondyloarthropathies study group - Universidad de LA Sabana - Hospital Militar Central, Colombia, Colombia, ⁴Universidad Autónoma de chihuahua, Chihuahua, Mexico, ⁵Insituto Nacional de Cardiología Ignacio Chavez, Ciudad de México, Mexico, ⁶hospital general de mexico, Ciudad de México, Mexico
Background/Purpose: Spondyloarthritis (SpA) is a group of inflammatory rheumatic diseases that have some key features in common. According to ASAS, this condition is classified into…

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