Abstracts tagged "Spondyloarthropathies"

Abstract Number: 2334 • ACR Convergence 2024
Characteristics of Patients with Psoriatic Arthritis Presenting with Axial Involvement: Results of a Prospective International Multicenter Study (AXIS)
Murat Torgutalp¹, Valderilio Azevedo², Xenofon Baraliakos³, Filip Van den Bosch⁴, Jürgen Braun⁵, Alberto Cauli⁶, Laura Coates⁷, Vinod Chandran⁸, Torsten Diekhoff⁹, Floris van Gaalen¹⁰, Rodrigo Garcia Salinas¹¹, Lianne S Gensler¹², Niti Goel¹³, Alice Gottlieb¹⁴, Desiree van der Heijde¹⁵, Philip Helliwell¹⁶, Kay Geert Hermann¹⁷, Umut Kalyoncu¹⁸, Uta Kiltz¹⁹, Robert Lambert²⁰, Ying Ying Leung²¹, Maria Llop²², Alejandra Lopez²³, Miranda van Lunteren²⁴, Ajesh Maharaj²⁵, Walter Maksymowych²⁶, Helena Marzo-Ortega²⁷, Ashish J Mathew²⁸, Philip Mease²⁹, Peter Nash³⁰, Mikkel Ostergaard³¹, Fabian Proft³², Mikhail Protopopov³³, Sherry Rohekar³⁴, RUXANDRA ELENA SCHIOTIS³⁵, Joachim Sieper³⁶, Enrique R. Soriano³⁷, Lai-shan Tam³⁸, James Wei³⁹, Nelly Ziade⁴⁰, Dafna Gladman⁴¹ and Denis Poddubnyy⁴², and AXIS Cohort Investigators, ¹Charite Universitatsmedizin - Berlin, Berlin, Germany, ²Department of Internal Medicine, Universidade Federal of Paraná, Curitiba, Brazil, Curitiba, Brazil, ³Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, ⁴Ghent University Hospital, Ghent, Belgium, ⁵Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany., Herne, Germany, ⁶University of Cagliari, Cagliari, Italy, ⁷University of Oxford, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom, ⁸University of Toronto, Toronto, ON, Canada, ⁹Charite Universitatsmedizin Berlin, Berlin, Germany, ¹⁰LUMC, Leiden, Zuid-Holland, Netherlands, ¹¹Hospital Italiano La Plata, La Plata, Argentina, ¹²Department of Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ¹³Caduceus Biomedical Consulting, Duke University, Durham, NC, ¹⁴Department of Dermatology, Icahn School of Medicine, New York, NY, USA., New York, NY, ¹⁵Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, ¹⁶Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK., Leeds, United Kingdom, ¹⁷Charite Medical School, Berlin, Germany, ¹⁸Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, ¹⁹Rheumazentrum Ruhrgebiet Herne, Ruhr-University, D-44649 Herne, Germany, ²⁰University of Alberta, Edmonton, AB, Canada, ²¹Singapore General Hospital, Singapore, Singapore, ²²Hospital Parc Tauli, Sabadell, Spain, ²³Centro Dermatológico del Country, Guadalajara, Jalisco, Mexico, Guadalajara, Mexico, ²⁴Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands, ²⁵Department of Internal Medicine & Therapeutics, Faculty of Health Sciences. Walter Sisulu University, Eastern Cape, South Africa, Eastern Cape, South Africa, ²⁶Department of Medicine, University of Alberta, Edmonton, AB, Canada; CARE Arthritis, Edmonton, AB, Canada, Edmonton, Canada, ²⁷NIHR Leeds BRC, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK., Leeds, United Kingdom, ²⁸Christian Medical College, Vellore, Tamil Nadu, India, ²⁹Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA, ³⁰School of Medicine, Griffith University, Sunshine Coast, Queensland, Australia, ³¹Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark, ³²Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ³³Charite – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ³⁴Western University, London, Ontario, Canada, London, Canada, ³⁵SPITAL CLINIC DE BOLI INFECTIOASE CLUJ NAPOCA, Cluj-Napoca, Romania, ³⁶Charité University Medicine Berlin, Berlin, Germany, ³⁷Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ³⁸The Chinese University of Hong Kong, New Territories, Hong Kong, ³⁹Chung Shan Medical University Hospital; China Medical University, Taichung, Taiwan (Republic of China), ⁴⁰Saint-Joseph University, Beirut, Lebanon, ⁴¹University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁴²Charite-Universitatsmedizin Berlin, Berlin, Germany
Background/Purpose: Axial involvement, affecting the sacroiliac joints (SIJ) and/or spine, is a clinically relevant manifestation of psoriatic arthritis (PsA) that can influence management strategies. Previous…
Abstract Number: 0051 • ACR Convergence 2023
CD14+CD64+ Classical Monocytes Are the Main Producers of IL-23 at the Enthesis
Nicole McDermott¹, Thomas Macleod¹, Ala Altaie¹, Liz Straszynski², Robert Dunsmuir³, Vishal Borse³, Peter Loughenbury³, Davide Simone⁴, Stevephen Sansom⁴, Christopher Buckley⁴ and Dennis McGonagle⁵, ¹University of Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom, ²Leeds Institute of Medical Research at St. James’s, Leeds, United Kingdom, ³Leeds Teaching Hospital NHS Trust, Leeds, United Kingdom, ⁴Kennedy Institute of Rheumatology, Oxford, United Kingdom, ⁵Leeds Biomedical Research Centre, University of Leeds, Leeds, United Kingdom
Background/Purpose: IL-23 is a key cytokine involved in diseases such as psoriasis, psoriatic arthritis and spondyloarthropathies (SpA) and inflammatory bowel disease.IL-23 is produced by activated…
Abstract Number: 1032 • ACR Convergence 2023
“Not of Your Ethnicity”: A Qualitative Study Exploring Diverse Patient Experiences in Axial Spondyloarthritis (axSpA)
Bryanna Mantilla¹, K Wysham², Jean liew³ and Grant Hughes¹, ¹University of Washington, Seattle, WA, ²VA Puget Sound/University of Washington, Seattle, WA, ³Boston University, Boston, MA
Background/Purpose: Axial spondyloarthritis (axSpA) can result in significant morbidity. Existing studies suggest functional impairment and inflammation may be worse in Black and Latine patients. However,…
Abstract Number: 1880 • ACR Convergence 2023
Performance of Machine Learning Algorithms in Discriminating Spondyloarthritis Features on Magnetic Resonance Imaging: A Systematic Review and Meta-analysis
Sun Jae Moon¹, Seulkee Lee¹, Seonyoung Kang¹, Hyungjin Kim¹, Jaejoon Lee¹, Jinseok kim², Eun-Mi Koh³, Jinseub Hwang⁴ and Hoon-Suk Cha¹, ¹Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, ²Division of Rheumatology, Department of Internal Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, South Korea, ³Health Insurance Review and Assessment Service, Seoul, South Korea, ⁴Department of Data Science, Daegu University, Gyeongsan, South Korea
Background/Purpose: The diagnostic role of Magnetic Resonance Imaging (MRI) for axial spondyloarthritis(axSpA) has grown since introducing the ASAS criteria for axSpA. Recent advances in machine…
Abstract Number: 0216 • ACR Convergence 2023
High Immunogenicity of mRNA Covid-19 Vaccine Booster in Immune Mediated Inflammatory Disease
Rebecca Haberman¹, Rebecca Blank², Paula Rackoff², Gary Solomon³, Samrachana Adhikari¹, Natalie Azar⁴, Ramin Herati¹, Pamela Rosenthal⁵, Peter Izmirly⁶, Jonathan Samuels⁷, Brian Golden⁸, Soumya Reddy⁵, Mark Mulligan¹ and Jose Scher⁶, ¹NYU Grossman School of Medicine, New York, NY, ²New York University, New York, NY, ³NYU Langone School of Medicine, Hartsdale, NY, ⁴NYU Langone, New York, NY, ⁵NYU School of Medicine, New York, NY, ⁶New York University School of Medicine, New York, NY, ⁷NYU Langone, Rye Brook, NY, ⁸NYU Langone Medical Center - NYU Hospital for Joint Diseases, New York, NY
Background/Purpose: Patients with immune-mediated inflammatory disorders (IMIDs) have an inherently heightened susceptibility to infection and may be considered high risk for COVID-19, yet IMID populations…
Abstract Number: 1346 • ACR Convergence 2023
Semen Analysis of Patients with Psoriatic Arthritis, Axial Spondyloarthritis and Healthy Controls
Katya Meridor¹, Shimi Barda², Ofir Elalouf², Victoria Furer², Sara Pel³, Hila Nochomovitz⁴, michael zisapel², Jonathan Wollman², Reut Tzemach², Mark Berman⁵, Sara Borok⁶, Hagit Sarbagil-Maman⁷, Hagit Padova⁸, David levartovsky², Tzippy Shochat⁹, Daphna Paran², Ron Hauser², Ori Elkayam² and Ari Polachek⁶, ¹Tel Aviv Medical Center, Kfar Saba, Israel, ²Tel Aviv Medical Center, Tel Aviv, Israel, ³Tel Aviv Medical Center, Modiin, Israel, ⁴Ichilov, Tel Aviv, Israel, ⁵Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ⁶Sourasky Medical Center, Tel Aviv, Israel, ⁷Tel Aviv Sourasky Medical center, Kiryat Ono, Israel, ⁸Tel Aviv Medical center, Petah-Tikva, Israel, ⁹Rabin Medical Center, Modiin, Israel
Background/Purpose: Psoriatic arthritis (PsA) and axial spondyloarthritis (AxSpA) are commonly diagnosed in young males in their reproductive years. However, only a few studies have investigated…
Abstract Number: 1886 • ACR Convergence 2023
Costotransverse Joint Ankylosis and Association with Syndesmophyte Progression in Patients with Radiographic Axial Spondyloarthritis
Hong Ki Min¹, Se Hee Kim², Hae-Rim Kim³, Sang-Heon Lee¹ and Sang-Hoon Lee², ¹Konkuk University School of Medicine, Seoul, South Korea, ²Kyung Hee University Hospital at Gangdong, Seoul, South Korea, ³Rheumatology, Konkuk University Medical Center, Seoul, South Korea
Background/Purpose: Costotransverse joint ankylosis in radiographic axial spondyloarthritis (r-axSpA) patients was measured. Furthermore, the association between syndesmophyte progression assessed by CT syndesmophyte score (CTSS) and…
Abstract Number: 0452 • ACR Convergence 2023
Real Life Safety and Survival of Targeted Therapies in Arthritis Patients over Age of 65
Elena Grau Garcia¹, Pablo Francisco Muñoz Martínez², Laura Mas Sanchez³, Alba Maria Torrat Noves¹, Daniel Ramos Castro¹, Carmen Riesco Barcena¹, Anderson Victor Huaylla Quispe¹, Iago Alcantara Alvarez¹, Belen Villanueva Mañez¹, Samuel Leal Rodriguez¹, Ines Canovas Olmos¹, Hikmat Charia¹, Marta De la Rubia Navarro¹, Luis Gonzalez Puig¹, Jose Ivorra Cortes¹, Isabel Martinez Cordellat¹, Carmen Najera Herranz¹, Rosa Negueroles Albuixech¹, Jose Eloy Oller Rodriguez¹, Ernesto Tovar Sugrañes¹, Elvira Vicens Bernabeu¹ and Jose Andres Roman Ivorra⁴, ¹Rheumatology Department. HUP La Fe, Valencia, Spain, ²Rheumatology Department. HUP La Fe, Sagunto, Spain, ³Rheumatology Department. HUP La Fe, Valéncia, Spain, ⁴Hospital Universitari i Politècnic la Fe, Valencia, Spain
Background/Purpose: Prognosis for chronic inflammatory arthritis is drastically improved over previous decades and older patients are treated with targeted therapies (TTs) (biological or synthetic targeted…
Abstract Number: 1392 • ACR Convergence 2023
Improving the Diagnostic Accuracy in Axial Spondyloarthritis: Interim Results of a Nationwide Telemedicine Project
Denis Poddubnyy¹, Marc Kämmerer², Marcus Kremers³, Berit Schoppen³, Charlotte Arens³, Annette Wiedon⁴, Imke Redeker⁵ and Xenofon Baraliakos⁶, ¹Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany, ²VISUS Health IT GmbH, Bochum, Germany, ³MedEcon Telemedizin GmbH / MedEcon Ruhr GmbH, Bochum, Germany, ⁴Novartis Pharma GmbH, Nürnberg, Germany, ⁵Ruhr Universität Bochum, Bochum, Germany, ⁶Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany
Background/Purpose: Axial spondyloarthritis (axSpA) is often diagnosed late, while there is also a problem of over- and misdiagnosis in patients with chronic back pain. Imaging,…
Abstract Number: 1892 • ACR Convergence 2023
Sacroiliac Bone Marrow Oedema on Postpartum MRI Does Not Result in Significant SpA-like Structural Lesions: Results of a 5-year Follow-up Study
De Meester Liesbet¹, Gaelle Varkas², Manouk de Hooge³, Ann-Sophie De Craemer⁴, Nele Herregods⁵, Lennart Jans⁵, Philippe Carron⁶, Dirk Elewaut⁷ and Filip Van den Bosch⁸, ¹Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, ²Dept. of Rheumatology, Ghent University Hospital, Ghent, Belgium, ³Ghent University Hospital, Hesperange, Luxembourg, ⁴Ghent University Hospital, Gent, Belgium, ⁵Department of Radiology, Ghent University Hospital, Ghent, Belgium, ⁶UZ Gent, Gent, Belgium, ⁷Ghent University and VIB Center for Inflammation Research, Ghent, Belgium, ⁸Department of Internal Medicine and Pediatrics, Ghent University and VIB Center for Inflammation Research, Ghent, Belgium
Background/Purpose: Sacroiliac bone marrow oedema (BMO) on MRI, immediately after childbirth, has been observed in a large proportion of postpartum women and appears to be…
Abstract Number: 0484 • ACR Convergence 2023
Higher Levels of High-sensitivity CRP Are Associated with Future Risk of Developing Psoriatic Arthritis Among Patients with Psoriasis: A Prospective Cohort Study
Lihi Eder¹, Vinod Chandran², Cheryl Rosen³, Richard J. Cook⁴ and Dafna Gladman⁵, ¹Women’s College Research Institute, Division of Rheumatology, University of Toronto, Toronto, ON, Canada, ²Schroeder Arthritis Institute, Krembil Research Institute, University Health Network and Division of Rheumatology, Department of Medicine, University of Toronto, Toronto, ON, Canada, ³Division of Dermatology, Toronto Western Hospital, Toronto, ON, Canada, ⁴Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada, ⁵Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Department of Medicine, University of Toronto, Toronto, ON, Canada
Background/Purpose: Simple and accessible biomarkers that predict the development of psoriatic arthritis (PsA) among psoriasis patients are critically needed to improve early detection of high-risk…
Abstract Number: 1398 • ACR Convergence 2023
A Deep Learning Algorithm for MRI Spinal Inflammation in Axial Spondyloarthritis
Shirley Chiu Wai Chan¹, Ying Ying Lin², Ho Yin Chung¹, Kam Ho Lee³ and Peng Cao², ¹Divison of Rheumatology and Clinical Immunology, Department of Medicine, Queen Mary Hospital, the University of Hong Kong, Hong Kong, Hong Kong, ²Department of Diagnostic Radiology, the University of Hong Kong, Hong Kong, Hong Kong, ³Department of Radiology, Queen Mary Hospital, Hong Kong, Hong Kong, Hong Kong
Background/Purpose: Deep learning has achieved wide applications in different areas of medical imaging analysis. Limited studies have explored the use of deep learning for imaging…
Abstract Number: 2199 • ACR Convergence 2023
Four-year Secukinumab Treatment Outcomes in Axial Spondyloarthritis and Psoriatic Arthritis Patients Treated in Routine Care: Results from the EuroSpA Collaboration
Marion Pons¹, Stylianos Georgiadis¹, Zohra Faizy Ahmadzay², Mikkel Østergaard³, Bente Glintborg¹, Jette Heberg¹, Sara Nysom Christiansen¹, Simon Horskjær Rasmussen¹, Isabel Castrejon⁴, Fernando Alonso⁵, Karin Laas⁶, Sigrid Vorobjov⁷, Nikita Khmelinskii⁸, Jakub Zavada⁹, Adrian Ciurea¹⁰, Michael Nissen¹¹, Brigitte Michelsen¹², Pawel Mielnik¹³, Anne Gitte Loft¹⁴, Ziga Rotar¹⁵, Katja Perdan Pirkmajer¹⁶, Gary Macfarlane¹⁷, Gareth T. Jones¹⁷, Dan Nordstrom¹⁸, Anna-Mari Hokkanen¹⁹, Irene van der Horst-Bruinsma²⁰, Johan Karlsson Wallman²¹, Bjorn Gudbjornsson²², olafur Palsson²³, Merete Hetland¹ and Lykke Ørnbjerg¹, ¹Copenhagen Center for Arthritis Research, Rigshospitalet, Copenhagen, Denmark, ²Rigshospitalet Glostrup, University of Copenhagen, Glostrup, Denmark, ³Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark, ⁴Hospital Universitario Gregorio Marañón, Madrid, Spain, ⁵Spanish Society of Rheumatology, Madrid, Spain, ⁶Department of Rheumatology, East-Tallinn Central Hospital, Tallinn, Estonia, ⁷National Institute for Health Development, Tallinn, Estonia, ⁸Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal, ⁹Institute of Rheumatology; Charles University, Prague, Czech Republic, ¹⁰University Hospital Zurich, Zürich, Switzerland, ¹¹Geneva University Hospitals, Geneva, Switzerland, ¹²Rigshospitalet Glostrup; Diakonhjemmet Hospital; Sørlandet Hospital, Copenhagen, Denmark, ¹³Section for Rheumatology, Helse Førde, Førde, Norway, ¹⁴Aarhus University, Horsens, Denmark, ¹⁵University Medical Centre Ljubljana, Ljubljana, Slovenia, ¹⁶University Medical Centre Ljubljana; University of Ljubljana, Ljubljana, Slovenia, ¹⁷Aberdeen Centre for Arthritis and Musculoskeletal Health (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ¹⁸Helsinki University Hospital, Helsinki, Finland, ¹⁹Departments of Medicine and Rheumatology, Helsinki University Hospital, Helsinki, Finland, ²⁰Rheumatology, Radboud University Medical Center, Nijmegen, Netherlands, ²¹Lund University and Skåne University Hospital, Lund, Sweden, ²²Centre for Rheumatology Research, University Hospital, Reykjavik, Iceland, ²³Faculty of Medicine, University of Iceland, Reykjavik, Iceland
Background/Purpose: Axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) are part of the spondylarthritis spectrum that can be treated with secukinumab, a fully human IgG1 monoclonal…
Abstract Number: 0493 • ACR Convergence 2023
Axial Disease Activity in Psoriatic Arthritis Is Higher in Patients with Carotid Plaque
Rosa Arvizu-Rivera¹, Valeria Gonzalez-Gonzalez², Dionicio A. Galarza-Delgado³, Iris Colunga³, José Ramón Azpiri-López³, Victor Beltran⁴, Angel Arias Peralta⁵ and Jesus Alberto Cardenas-De la Garza⁶, ¹Hospital Universitario "Dr. José Eleuterio Gonzalez", Escobedo, Mexico, ²Universidad Autónoma de Nuevo León, Monterrey, Mexico, ³Hospital Universitario UANL, Monterrey, Mexico, ⁴Rheumatology Service Hospital Universitario "Dr. José Eleuterio González", Monterrey, Mexico, ⁵Medicine Faculty, Universidad Autonoma De Nuevo Leon, Monterrey, Mexico, ⁶Hospital Universitario "Dr. José Eleuterio González", San Nicolas, Mexico
Background/Purpose: Approximately half of the patients with psoriatic arthritis (PsA) present with axial disease. Previously, it was reported that PsA-patients with axial involvement present a…
Abstract Number: 1405 • ACR Convergence 2023
Diagnostic Delay of Axial Spondyloarthritis in African American Patients
John Byun¹, Hans Vitzthum von Eckstaedt¹, Kichul Ko² and Reem Jan¹, ¹University of Chicago, Chicago, IL, ²The University of Chicago, Chicago, IL
Background/Purpose: The identification of axial spondyloarthritis (axSpA) remains challenging. The initial presentation is not always immediately apparent as an inflammatory disease, potentially leading to years…

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