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Abstracts tagged "Spondyloarthropathies"

  • Abstract Number: 1760 • ACR Convergence 2024

    A Phase 2 Multicenter, Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of a Mitogen-activated Protein Kinase-Activated Protein Kinase 2 (MK2) Inhibitor in Active Ankylosing Spondylitis

    Walter Maksymowych1, Robert Lambert1, Paula Śliwinska-Stańczyk2, Piotr Adrian Klimiuk3, Anusha Yeshokumar4, Elizabeth Cerullo4, Rebecca Kepich4, Chahin Pachai4 and Steven Greenberg4, 1University of Alberta, Edmonton, AB, Canada, 2Centrum Medyczne ReumaPark, Warsaw, Poland, 3Medical University of Bialystok and Inter Clinic Piotr Adrian Klimiuk, Department of Rheumatology and Internal Diseases, Białystok, Poland, 4Bristol Myers Squibb, Princeton, NJ

    Background/Purpose: CC-99677 (also known as BMS-986371) is a novel, orally bioavailable, small-molecule covalent inhibitor of mitogen-activated protein (MAP) kinase-activated protein kinase 2 (MK2). The MK2…
  • Abstract Number: 0141 • ACR Convergence 2024

    The Effect of Systemic Immunosuppressive Therapies on Cardiovascular Risk in Psoriatic Arthritis Patients

    Melody Esmaeili1, Linh Truong2, Nicole Ridolfi3, Eugenia Chen4 and Maida wong5, 1University of California, Irvine, Orange, CA, 2University of California, Los Angeles, Los Angeles, CA, 3University of California, Irvine, Newport Beach, CA, 4Long Beach VA Hospital, Irvine, CA, 5Long Beach VA Hospital, Los Angeles, CA

    Background/Purpose: Evidence demonstrates an increased prevalence of atherosclerotic cardiovascular disease (ASCVD) among psoriatic arthritis (PsA) patients. However, the relationship between immunosuppressive therapies and the development of ASCVD remains unclear.…
  • Abstract Number: 0604 • ACR Convergence 2024

    Secular Trends in Biologic Prescribing for Psoriasis and Psoriatic Arthritis, 2014-2024

    Mahum Mirza1, Jean Liew2, Michael Putman3 and Shikha Singla1, 1Medical College of Wisconsin, Milwaukee, WI, 2Boston University Chobanian & Avedisian School of Medicine, Boston, MA, 3The Medical College of Wisconsin, Milwaukee, WI

    Background/Purpose: Treatment options for psoriasis or psoriatic arthritis (PsA) have expanded in the past decade. Secular trends in biologic disease modifying antirheumatic drug (bDMARD) prescribing…
  • Abstract Number: 1850 • ACR Convergence 2024

    Exhausted T-cells Are Increased in Autoimmune Diseases and Predict Response to Anti-TNF in RA and SPA Patients

    Samuel Bitoun1, Marie Naigeon2, Matthieu Roulleaux- Dugage2, Caroline De Oliveira2, Caroline Berthot2, Xavier Mariette3, Gaetane Nocturne3 and Nathalie Chaput-Gras2, 1Service de Rhumatologie, Hôpital Bicêtre, AP-HP, Le Kremlin-Bicetre, France, 2Laboratoire d'immunomonitoring en Oncologie, INSERM US23, CNRS UMS 3655, Gustave Roussy,, Villejuif, France, 3Service de Rhumatologie, Hôpital Bicêtre, AP-HP, Le Kremlin Bicetre, France

    Background/Purpose: Exhaustion can occur after prolonged activation of T cells limiting their immunosurveillance function leading to cancer emergence. Among the exhaustion markers expressed on T…
  • Abstract Number: 0230 • ACR Convergence 2024

    Spine and Sacroiliac Joint Involvement in Newly Diagnosed Patients with Inflammatory Bowel Disease – Clinical and MRI Findings from a Population-Based Cohort Study

    Nora Vladimirova1, Jakob Møller2, Mohamed Attauabi2, Gorm Madsen3, Lene Terslev4, Charlotte Wiell5, Viktoria Fana6, Sanja Bay Hansen3, Hartwig Siebner3, Jakob Seidelin2, Flemming Bentsen3, Kasper Gosvig7, Johan Burisch3 and Mikkel Ostergaard8, 1Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Righospitalet, Copenhagen, Denmark, 2Herlev and Gentofte Hospital, copenhagen, Denmark, 3Hvidovre Hospital, copenhagen, Denmark, 4Rigshospitalet-Glostrup & COPECARE, Glostrup, Denmark, 5Rigshospitalet-Glostrup, Copenhagen, Denmark, 6Rigshospitalet-Glostrup, Glostrup, Denmark, 7Department of Radiology, Copenhagen University Hospital Herlev-Gentofte, Herlev, Denmark, 8Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark

    Background/Purpose: In patients with inflammatory bowel disease (IBD), coexistence of spondyloarthritis (SpA), the most common extraintestinal manifestation, is associated with poor outcomes and impaired quality…
  • Abstract Number: 0817 • ACR Convergence 2024

    2024 Clinical Practice Guideline for the Diagnosis and Treatment of Chronic Nonbacterial Osteitis (CNO) in Adults

    Elizabeth Winter, Olaf Dekkers and Anne Leerling, and the Expert Consensus Panel for Chronic Nonbacterial Osteitis (CNO) in Adults, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Adults with sterile bone inflammation are variably labelled as Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis (SAPHO)-syndrome, chronic nonbacterial osteomyelitis, chronic recurrent multifocal osteomyelitis (CRMO), pustulotic…
  • Abstract Number: 1875 • ACR Convergence 2024

    Assessing the PULSAR (Program to Understand the Longterm Outcomes in Spondyloarthritis) Registry for Environmental Determinants of Heath Research

    Liya Stolyar1, Diane Mar2, Yuhan Liu3, Esther Velasquez4, orr Sharpe5, Michael Weisman6, Liron Caplan7 and suzanne Tamang8, 1Palo Alto VA Medical Center/Stanford, Stanford, CA, 2Palo Alto VA Medical Center/Stanford University Medical Center, Palo Alto, CA, 3Stanford Medicine Quantitative Sciences Unit, Palo Alto, CA, 4Stanford Center for Population Health Sciences, Palo Alto, CA, 5Department of Immunology and Rheumatology, Stanford University, Stanford, CA, 6Stanford University, Los Angeles, CA, 7Univ of Colorado School of Medicine/Rocky Mtn Regional Veterans Affairs Medical Center, Aurora, CO, 8Stanford University, Atherton, CA

    Background/Purpose: Acute exposure to air pollution has been associated with flares of psoriasis and chronic inflammatory arthritides in prior studies.  However, the impact of air pollution,…
  • Abstract Number: 0234 • ACR Convergence 2024

    MRI of Sacroiliac Joints: Is Contrast Necessary for the Detection of Sacroiliitis?

    Damira Sereda1, Arun Venkataraman1, Harlan Stock1 and Andras Perl2, 1SUNY Upstate Medical University, Syracuse, NY, 2SUNY, Syracuse, NY

    Background/Purpose: Spondyloarthropathy (SpA) encompasses several conditions, such as ankylosing spondylitis, psoriatic arthritis, reactive arthritis, arthritis linked with inflammatory bowel disease, and undifferentiated spondyloarthritis [1]. Sacroiliitis…
  • Abstract Number: 0820 • ACR Convergence 2024

    The Classification in Axial Spondyloarthritis Inception Cohort Study: Performance of the 2009 Assessments in Spondyloarthritis International Society Classification Criteria

    Walter Maksymowych1, Desiree van der Heijde2, Liron Caplan3, Robert Landewé4, Lianne S Gensler5, Pedro M. Machado6, Alexandre Sepriano7, Floris van Gaalen8, Miranda van Lunteren9, Ben Vandermeer10, Joachim Sieper11, Atul Deodhar12 and Martin Rudwaleit13, and on behalf of CLASSIC Study investigators, 1University of Alberta, Edmonton, AB, Canada, 2Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, 3Rocky Mountain Regional VAMC, Aurora, CO, 4Amsterdam University Medical Center, Meerssen, Netherlands, 5Department of Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, 6Department of Rheumatology, University College London Hospitals NHS Foundation Trust; and Department of Rheumatology, Northwick Park Hospital, London North West University Healthcare NHS Trust; and Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, United Kingdom, 7Leiden University Medical Centre, Portela Loures, Portugal, 8LUMC, Leiden, Zuid-Holland, Netherlands, 9Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands, 10University of Alberta, Edmonton, Canada, 11Charité University Medicine Berlin, Berlin, Germany, 12Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR, 13University of Bielefeld, Klinikum Bielefeld, Bielefeld, Germany

    Background/Purpose: The 2009 ASAS classification criteria had sensitivity of 83% and specificity of 84% for a rheumatologist diagnosis of axSpA. However, their implementation revealed varying…
  • Abstract Number: 2057 • ACR Convergence 2024

    Clinical Features of Autoimmune Uveitis and Associated Factors with Reactivation Subtype Presentation from a Peruvian Multidisciplinary Reference Center

    Hugo Madariaga.Ch1, Valery Ascuña2 and RV, Gamboa-Cardenas3, and Grupo Peruano de Estudio de Enfermedades Autoinmunes Sistémicas , Universidad Científica del Sur, 1Clínica del Sur Sanna. Arequipa-Perú, Arequipa, Peru, 2Oftalmosalud Clinical Center. Arequipa-Perú, Arequipa, Peru, 3Universidad Científica del Sur, Lima, Lima, Peru

    Background/Purpose: To determine clinical features of autoimmune uveitis (AU) and the associated factors with the reactivation subtype Methods: A transversal analysis from single center cohort (ophthalmologic/rheumatologic…
  • Abstract Number: 0352 • ACR Convergence 2024

    Fast-tracking Axial Spondyloarthritis Diagnosis: A Novel Approach to Public Health Advocacy and Awareness

    Joe Eddison, National Axial Spondyloarthritis Society, London, United Kingdom

    Background/Purpose: The Act on Axial SpA campaign is dedicated to minimising the lengthy 8.5-year delay in diagnosing axial spondyloarthritis (axial SpA) by implementing a pioneering…
  • Abstract Number: 0821 • ACR Convergence 2024

    Validation of ASAS Preliminary Data-Driven MRI Lesion Cut-offs for a Positive MRI of the Sacroiliac Joints in Patients with Axial Spondyloarthritis and Subgroups with Psoriasis, Iritis, and Colitis

    Susanne Pedersen1, Ulrich Weber2, Ozun Bayindir Tsechelidis3, Robert Lambert4, Joel Paschke5, Stephanie Wichuk4 and Walter Maksymowych4, 1Rigshospitalet, København, Denmark, 2Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, 3Ottawa University, Ottawa, ON, Canada, 4University of Alberta, Edmonton, AB, Canada, 5CARE Arthritis, Edmonton, AB, Canada

    Background/Purpose: Recent analysis of MRI scans from the 2009 ASAS classification cohort has led to a new proposal for the application of more stringent MRI…
  • Abstract Number: 2153 • ACR Convergence 2024

    Construct Validity of the IDEOM Musculoskeletal Questionnaire (IDEOM MSK-Q) Using Data from the Cohort for Psoriasis and Psoriatic Arthritis Registry (COPPAR)

    Lourdes Perez Chada1, Ruogu Li2, vivi feathers2, Kumiko Schnock2, Helen Early2, Grace Carter2, Neda Shahriari2, Arianna Zhang2, Jing Cui3, Michael Weinblatt4, Nancy Shadick2, Alice Gottlieb5 and Joseph Merola6, 1Harvard Medical School, Wayland, MA, 2Brigham and Women's Hospital, Boston, MA, 3Brigham Women's Hospital, Boston, MA, 4Brigham and Women's Hospital/ Harvard Medical School, Waban, MA, 5Icahn School of Medicine at Mount Sinai, Department of Dermatology, Seattle, WA, 6UT Southwestern Medical Center, Newton, MA

    Background/Purpose: Patients with psoriasis often present with musculoskeletal (MSK) symptoms, yet validated instruments to measure MSK symptoms in this population are limited. The IDEOM MSK-Q…
  • Abstract Number: 0356 • ACR Convergence 2024

    Patient Satisfaction and Experience After a Switch to a Citrate-free High-concentration Adalimumab Biosimilar. Results from a Prospective Multicentric Real-world Study

    Hubert Marotte1, Laure Gossec2, Vered ABITBOL3, Eric SENBEL4, Guillaume BONNAUD5, Xavier ROBLIN6, Yoram BOUHNIK7, Stéphane NANCEY8, Nicolas MATHIEU9, jérôme FILIPPI10, Lucine VUITTON11, Stéphane NAHON12, Azeddine Dellal12, Alice DENIS13, Caroline HABAUZIT13, Salim BENKHALIFA13 and Guillaume BOUGUEN14, 1Université Jean Monnet, CHU Saint-Etienne, Mines Saint-Etienne, INSERM SAINBIOSE 1059, Saint-Etienne, France, 2Sorbonne Université, Paris, France, 3Cochin University Hospital, Paris, France, 4Medical practice, Marseille, Marseille, France, 5Ambroise Paré Clinic, Toulouse, France, 6Saint-Etienne University Hospital, Saint-Etienne, France, 7Institut des MICI, Paris IBD Center, Neuilly-Sur-Seine, France, 8Hospices Civils de Lyon, Lyon, France, 9Clinic of Cèdres, Echirolles, France, 10Saint-Jean Clinic, Cagnes sur Mer, France, 11Besançon university hospital, Besançon, France, 12Groupe Hospitalier Intercommunal Le Raincy-Montfermeil, Montfermeil, France, 13Celltrion Healthcare France, Issy Les Moulineaux, France, 14Rennes University Hospital, Rennes, France

    Background/Purpose: Biosimilars (BioS) are cost-effective alternatives to reference products for patients with chronic inflammatory rheumatic diseases (CIRD) and inflammatory bowel diseases (IBD), but treatment adherence…
  • Abstract Number: 0851 • ACR Convergence 2024

    Diagnostic Ultrasound Enthesitis Tool (DUET) for Psoriatic Arthritis: The Distribution of Elementary Lesions Is Influenced by Site

    Lihi Eder1, Ricardo Acayaba de Toledo2, Fahmeen Afgani3, Catherine Bakewell4, Philippe Carron5, Basant Elnady6, Amir Haddad7, Arthur Kavanaugh8, Arnon Katz9, Minna Kohler10, josefina marin11, NZEUSSEU TOUKAP Adrien12, Marcos Rosemffet13, Ari Polachek14, Ernesto Rodriguez15, Ágnes Sarolta Szentpétery16, Abha Singh17, Maria S. Stoenoiu18, Ilaria Tinazzi19, Janeth Yinh10, Gurjit Kaeley20 and Sibel Aydin21, 1University of Toronto, Women’s College Hospital and Department of Medicine, Toronto, ON, Canada, 2FAMERP, São José do Rio Preto, Brazil, 3Women's College Hospital, Toronto, Canada, 4Intermountain Health Care, Salt Lake City, UT, 5UZ Gent, Gent, Belgium, 6Al Hada Forces Hospital, Rheumatology Department, Taif, Saudi Arabia, 7Carmel Medical Centre, Haifa, Israel, 8University of California San Diego, La Jolla, CA, 9GRAPPA - Patient Research Partner, Haifa, Israel, 10Massachusetts General Hospital, Boston, MA, 11Hospital Italiano de Buenos Aires, buenos aires, Argentina, 12Institut de Recherche Expérimentale et Clinique, Cliniques universitaires Saint-Luc, Université catholique de Louvain, St.-Lambrechts-Woluwe, Belgium, 13Instituto de Rehabilitación Psicofísica, Capital Federal, Argentina, 14Tel-Aviv Medical Center, Tel-Aviv, Israel, Petah-Tikva, Israel, 15Florida Medical Clinic, Tampa, FL, 16Uppsala University Hospital, Uppsala, Sweden, 17University of California, San Diego, San Diego, CA, 18Cliniques Universitaires Saint-Luc, Brussels, Belgium, 19Ospedale Sacro Cuore-Don Calabria, Verona, Italy, 20UF COM-J, Ponte Vedra Beach, FL, 21University of Ottawa - Ottawa, Ottawa, ON, Canada

    Background/Purpose: Enthesitis is a key domain in psoriatic arthritis (PsA). The Diagnostic Ultrasound Enthesitis Tool (DUET) study aims to develop a new PsA-specific sonographic scoring…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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