ACR Meeting Abstracts

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Abstracts tagged "spondyloarthritis"

  • Abstract Number: 0231 • ACR Convergence 2024

    Imaging Characteristics and Demographic Variations in Patients with Axial Spondylarthritis, Axial Psoriatic Arthritis, and Inflammatory Bowel Disease-Related Arthritis with Axial Involvement: Insights from a Single Center at Cleveland Clinic Abu Dhabi

    Rajaie Namas1, Ahlam Almarzooqi2, Sarah Al Qassimi3 and Esat Memisoglu3, 1Cleveland Clinic Abu Dhabi, Detroit, MI, 2Emirates Health Services, Sharjah, United Arab Emirates, 3Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates

    Background/Purpose: Spondyloarthropathies (SpAs) are a group of seronegative, inflammatory arthritides, including axial spondylarthritis (ax-SpA), axial psoriatic arthritis (ax-PsA), and inflammatory bowel disease related arthritis with…
  • Abstract Number: 0547 • ACR Convergence 2024

    EspANDE Project: Improvement of Primary Care-Rheumatology Coordination in Spondyloarthritis in a Health Area in Northern Spain

    Julio Sánchez-Martín1, Cristina Martinez-Dubois2, Javier Rueda Gotor3, Gabriel Pinedo-Lopez2, Alvaro Perez-Martin2, Roberto Gonzalez-Santamaria2, Belén Atienza-Mateo4, Vanesa Calvo-Rio5, Inigo Gonzalez-Mazon6, Natalia Palmou Fontana4, Enriqueta Peiro-Callizo2, Diana Prieto-Peña4, Lara Sanchez Bilbao7, Fernando Lopez-Gutierrez8 and Ricardo Blanco-Alonso9, 1Hospital Universitario 12 de Octubre, Madrid, Spain, 2Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, Santander, Cantabria, Spain, 3Hospital Sierrallana, Torrelavega, Cantabria, Spain, 4Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Cantabria, Spain, 5Valdecilla Hospital, Santander, Cantabria, Spain, 6H. U. Marques de Valdecilla, Santander, Cantabria, Spain, 7Rheumatology and Ophthalmology. Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, 8Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Cantabria, Spain, 9Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain

    Background/Purpose: Spondyloarthritis (SpA) constitutes a diverse set of inflammatory rheumatic diseases with a prevalence of 1.9% in the general population. Diagnostic delay, identified as a…
  • Abstract Number: 0565 • ACR Convergence 2024

    Low Vitamin D Serum Level Is a Risk Factor for Ankylosis in Axial Spondyloarthritis: Evidence from a Nested-Case-Control Study

    Anthony Lichaa1, Pauline KRUG1 and Adrien Nzeusseu Toukap2, 1Cliniques universitaires St-Luc, Brussel, Belgium, 2Cliniques universitaires Saint-Luc,, St.-Lambrechts-Woluwe, Belgium

    Background/Purpose: Axial spondyloarthritis (axSpA) is a progressive disease, characterized by chronic inflammation and progressive structural damage. However, the kinetic of progression to ankylosis and much…
  • Abstract Number: 0599 • ACR Convergence 2024

    Sex- related Differences in Efficacy of Biologics in Axial Spondyloarthritis: A Systematic Review and Meta-analysis

    Haseeb Chaudhary1, Omer Pamuk2, Sarah Abi Doumeth3, Ansaam Daoud4, Muhammad Shamim5 and Marina Magrey6, 1Case Western Reserve University, Westlake, OH, 2University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH, 3Case Western Reserve University/University Hospitals Cleveland Medical Center, Cleveland Heights, OH, 4Case Western Reserve University/University Hospitals, Akron, OH, 5University Hospitals/ Case Western Reserve University, Cuyahoga Falls, OH, 6Case Western Reserve University School of Medicine/University Hospitals, Richfield, OH

    Background/Purpose: There is limited information about sex-related differences in efficacy of biologics in axial spondyloarthritis (axSpA).  We hypothesized that females with axSpA are less likely…
  • Abstract Number: 1433 • ACR Convergence 2024

    Association of Contextual Factors with Sonographic Inflammatory and Structural Phenotypes in Psoriatic Arthritis Patients

    Andre Lucas Ribeiro1, Sydney Thib2, Kangping Cui3, Sahil Koppikar4 and Lihi Eder5, 1Women's College Hospital & University of Toronto, Porto Alegre, Rio Grande do Sul, Brazil, 2Women's College Research Institute, Toronto, Canada, 3Sunnybrook Hospital, Toronto, Gravenhurst, ON, Canada, 4Women's College Hospital & University of Toronto, Toronto, ON, Canada, 5University of Toronto, Women’s College Hospital and Department of Medicine, Toronto, ON, Canada

    Background/Purpose: Ultrasound (US) is a valuable tool for enhancing disease activity assessment in psoriatic arthritis (PsA) by providing detailed visualization of both inflammatory and structural…
  • Abstract Number: 1480 • ACR Convergence 2024

    Sustained Improvements with Bimekizumab in Spinal Mobility, Physical Function and Health-Related Quality of Life in Patients with Axial Spondyloarthritis: 2-Year Results from Two Phase 3 Studies

    Victoria Navarro Compán1, Maureen Dubreuil2, Karl Gaffney3, Jonathan Kay4, Christine de la Loge5, Ute Massow6, Vanessa Taieb7, Thomas Vaux8 and Atul Deodhar9, 1La Paz University Hospital, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain, 2Section of Rheumatology, Boston University School of Medicine, Boston, MA, 3Health Care - NHS, Norwich, United Kingdom, 4Division of Rheumatology, Department of Medicine, UMass Chan Medical School and UMass Memorial Medical Center, Worcester, MA, 5UCB Pharma, Brussels, Belgium, 6UCB Pharma, Monheim am Rhein, Germany, 7UCB Pharma, Colombes, France, 8UCB Pharma, Slough, United Kingdom, 9Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR

    Background/Purpose: In the phase 3 BE MOBILE 1 and 2 studies, bimekizumab (BKZ), a monoclonal IgG1 antibody that inhibits interleukin (IL)-17F in addition to IL-17A,…
  • Abstract Number: 2155 • ACR Convergence 2024

    Direct Comparison of Sleep Quality and Risk Factors for Poor Sleep Across Rheumatoid Arthritis, Axial Spondyloarthritis and Psoriatic Arthritis

    Dagna Polak1, Mateusz Wilk2, Piotr Kuszmiersz1, Glenn Haugeberg3, Mariusz Korkosz4 and Zofia Guła4, 1University Hospital in Cracow, Kraków, Poland, 2Univesity Hospital in Cracow, Kraków, Poland, 3Sørlandet Hospital, Kristiansand, Kristiansand, Norway, 4Department of Rheumatology and Immunology, Jagiellonian University Medical College, Kraków, Poland

    Background/Purpose: Sleep disorders are common among patients with inflammatory arthritis (IA) and have probably bilateral influence on disease activity and quality of life. Pathomechanism of…
  • Abstract Number: 2367 • ACR Convergence 2024

    Updated Long-Term Safety and Tolerability of Bimekizumab in Patients with Axial Spondyloarthritis and Psoriatic Arthritis: Pooled Results from Phase 2b/3 Studies

    Philip Mease1, Denis Poddubnyy2, Rajan Bajracharya3, Barbara Ink3, Alexander Marten4, Ute Massow4, Vishvesh Shende3, Myriam Manente5, Luke Peterson6, Katy White3, Peter Nash7 and Lianne S Gensler8, 1Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA, 2Charite-Universitatsmedizin Berlin, Berlin, Germany, 3UCB Pharma, Slough, United Kingdom, 4UCB Pharma, Monheim am Rhein, Germany, 5UCB Pharma, Braine-l'Alleud, Belgium, 6UCB Pharma, Morrisville, NC, 7School of Medicine, Griffith University, Sunshine Coast, Queensland, Australia, 8Department of Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA

    Background/Purpose: Bimekizumab (BKZ) is a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)‑17F in addition to IL‑17A. BKZ was generally well tolerated by patients (pts)…
  • Abstract Number: 0234 • ACR Convergence 2024

    MRI of Sacroiliac Joints: Is Contrast Necessary for the Detection of Sacroiliitis?

    Damira Sereda1, Arun Venkataraman1, Harlan Stock1 and Andras Perl2, 1SUNY Upstate Medical University, Syracuse, NY, 2SUNY, Syracuse, NY

    Background/Purpose: Spondyloarthropathy (SpA) encompasses several conditions, such as ankylosing spondylitis, psoriatic arthritis, reactive arthritis, arthritis linked with inflammatory bowel disease, and undifferentiated spondyloarthritis [1]. Sacroiliitis…
  • Abstract Number: 0548 • ACR Convergence 2024

    Associations and Impact of Kinesiophobia on Patient Reported Outcomes and Performance-based Mobility Measures in Patients with Axial Spondyloarthritis

    David Kiefer1, Juergen Braun2, Uta Kiltz3, Niklas Kolle1, Lucia Schneider1, Ioana Andreica4, Bjoern Buehring5, Philipp Sewerin6, Imke Redeker7, Styliani Tsiami8, Susanne Herbold9 and Xenofon Baraliakos8, 1Ruhr-Universität Bochum; Rheumazentrum Ruhrgebiet, Herne, Germany, 2Rheuma Praxis, Ruhr-University Bochum, Berlin, Germany, 3Rheumazentrum Ruhrgebiet Herne, Ruhr-University, D-44649 Herne, Germany, 4Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 5Bergisches Rheuma-Zentrum Wuppertal; Ruhr-Universität Bochum, Wuppertal, Germany, 6Ruhr-Universität Bochum, Rheumazentrum Ruhrgebiet, Herne, Germany, 7Ruhr Universität Bochum, Bochum, Germany, 8Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 9Rheumazentrum Ruhrgebiet, Herne, Herne, Germany

    Background/Purpose: Kinesiophobia, defined as the fear of movement, poses a significant barrier to effective rehabilitation, functional recovery, and adequate physical activity. To investigate the impact…
  • Abstract Number: 0566 • ACR Convergence 2024

    How Early Is Early? Unveiling Time to Diagnosis Since Symptom Onset and Its Determinants in Patients Suspected of Early Axial Spondyloarthritis: Data from the SPondyloArthritis Caught Early (SPACE) Cohort

    Mary Lucy Marques1, Desiree van der Heijde2, Liese de Bruin3, Miranda van Lunteren4, Robert Landewé5, Karen Minde Fagerli6, Maikel Van Oosterhout7, Floris van Gaalen8 and Sofia Ramiro9, 1Leiden University Medical Center, Coimbra, Zuid-Holland, Portugal, 2Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, 3Leiden University Medical Center, Leiden, Netherlands, 4Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands, 5Amsterdam University Medical Center, Meerssen, Netherlands, 6Diakonhjemmet Hospital, Oslo, Norway, 7Groene Hart Ziekenhuis, Gouda, the Netherlands, Gouda, Netherlands, 8LUMC, Leiden, Zuid-Holland, Netherlands, 9Leiden University Medical Center, Bunde, Netherlands

    Background/Purpose: Patients with chronic back pain (CBP) of less than two-years (2y) duration suspected of axial spondyloarthritis (axSpA) referred to the rheumatologist can be reliably…
  • Abstract Number: 0602 • ACR Convergence 2024

    Bimekizumab Impact on Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) Core Domains for Patients with Psoriatic Arthritis: Results up to 2 Years of Treatment Duration

    Joseph F. Merola1, Philip Mease2, Atul Deodhar3, Alice Gottlieb4, Barbara Ink5, Dirk de Cuyper6, Rajan Bajracharya5, Jérémy Lambert7, Jason Coarse8 and Laura Coates9, 1UT Southwestern Medical Center, Dallas, TX, 2Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA, 3Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR, 4Icahn School of Medicine at Mount Sinai, Department of Dermatology, Seattle, WA, 5UCB Pharma, Slough, United Kingdom, 6UCB Pharma, Brussels, Belgium, 7UCB Pharma, Colombes, France, 8UCB Pharma, Morrisville, NC, 9University of Oxford, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom

    Background/Purpose: The Group for Research and Assessment of Psoriasis and PsA (GRAPPA) domain‑based treatment recommendations for PsA focus on six key domains: peripheral arthritis, axial…
  • Abstract Number: 1434 • ACR Convergence 2024

    Prevalence of Liver Steatosis in Axial Spondyloarthritis : A Retrospective Study Using Computed Tomography Liver Minus Spleen Attenuation Ratio

    Léa Da silva1, olivier Fakih1, mickael chouk1, delphine weil-verhoeven2, DANIEL WENDLING3, CLEMENT PRATI4 and FRANK VERHOEVEN1, 1Service de rhumatologie, CHU de Besancon, Besançon, France, 2Service d'hépatologie, CHU de Besancon, Besançon, France, 3University Hospital, Besançon, France, 4Service de Rhumatologie, centre hospitalier régional universitaire Jean-Minjoz, Université de Franche-Comté, Besançon, France

    Background/Purpose: The management of axial spondyloarthritis (axSpA) comorbidities includes the metabolic syndrome (2). The latter includes steatotic liver disease (SLD) (3), which is present in…
  • Abstract Number: 1481 • ACR Convergence 2024

    Safety of Secukinumab in Patients with Psoriasis, Psoriatic Arthritis, Axial Spondyloarthritis and Hidradenitis Suppurativa: Updated Pooled Data from 69 Clinical Trials

    Atul Deodhar1, Iain McInnes2, Xenofon Baraliakos3, Alice Gottlieb4, Uta Kiltz5, Stefan Schreiber6, Braja Gopal Sahoo7, Weibin Bao8, Corine Gaillez9, Mercedes Bustamante9 and Philip Mease10, 1Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR, 2University of Glasgow, College of Medical Veterinary and Life Sciences, Glasgow, United Kingdom, 3Rheumazentrum Ruhrgebiet Herne, and Ruhr-University Bochum, Bochum, Germany, 4Icahn School of Medicine at Mount Sinai, Department of Dermatology, Seattle, WA, 5Rheumazentrum Ruhrgebiet Herne, Ruhr-University, D-44649 Herne, Germany, 6University Hospital Schleswig-Holstein, Kiel, Germany, Kiel, Germany, 7Novartis Healthcare Private Limited, Hyderabad, India, 8Novartis Pharmaceuticals Corporation, East Hanover, NJ, 9Novartis Pharma AG, Basel, Switzerland, 10Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA

    Background/Purpose: Secukinumab, a fully human anti-interleukin (IL)-17A monoclonal antibody, is approved for multiple immunological disorders, including moderate-to-severe plaque psoriasis (PsO), psoriatic arthritis (PsA), axial spondyloarthritis…
  • Abstract Number: 2156 • ACR Convergence 2024

    Differential Item Functioning of Inflammatory Back Pain Criteria in US Subpopulations

    Mark Hwang1, Seokhun Kim2, Shervin Assassi3, Alexis Ogdie4, Michael Weisman5, John Reveille6 and Charles Green2, 1Department of Internal Medicine, Division of Rheumatology, John P. and Katherine G. McGovern School of Medicine, UTHealth Houston, Houston, TX, 2UTHealth Houston, Houston, 3UTHealth Houston Division of Rheumatology, Houston, TX, 4Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 5Stanford University, Los Angeles, CA, 6UTHealth Houston Division of Rheumatology, Houston

    Background/Purpose: IInflammatory back pain (IBP) has clinical features that distinguish it from other back pain etiologies.  While there are established IBP criteria, in different subpopulations…
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