ACR Meeting Abstracts

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Abstracts tagged "spondyloarthritis"

  • Abstract Number: 0411 • ACR Convergence 2024

    Axial Radiographic Structural Damage in Enthesitis-Related Arthritis in Children and Young Adult Patients

    Annelyse de Araújo Pereira1, Marcelo Pinheiro2, Jade Dib Fernandez1, Ana Sakamoto3, Adham do Amaral e Castro1 and Maria Teresa Terreri4, 1UNIFESP-EPM, São Paulo, SP, Brazil, 2UNIFESP/ EPM, São Paulo, SP, Brazil, 3Federal University of São Paulo (UNIFESP), São Paulo, SP, Brazil, 4UNIFESP, São Paulo, SP, Brazil

    Background/Purpose: Enthesitis-related arthritis (ERA), a distinct subtype of juvenile idiopathic arthritis (JIA) related to HLA-B27 status and peripheral and axial involvement, presents with insidious onset…
  • Abstract Number: 0555 • ACR Convergence 2024

    The Effect of Alcohol Consumption on Clinical Outcomes and Structural Damage in Patients with Axial Spondyloarthritis: A Systematic Literature Review and Meta-Analysis

    Sinead Maguire1, Nigil Haroon2, Robert Inman3, Melanie Anderson4, Evelyne Gendron5 and Sindhu R. Johnson6, 1University of Toronto, University Health Network, Schroeder Arthritis Institute, Department of Rheumatology, Toronto, Canada, 2Department of Medicine/Rheumatology, University Health Network, Schroeder Arthritis Institute, University of Toronto, Toronto, ON, Canada, 3University Health Network, Toronto, ON, Canada, 4The Institute for Education Research, Library and Information Services, University Health Network, Toronto, ON, Canada, 5University of Toronto, University Health Network, Schroeder Arthritis Institute, Department of Rheumatology, Quebec City, QC, Canada, 6University of Toronto, Toronto, Canada

    Background/Purpose: Axial spondyloarthritis (axSpA) is a chronic progressive inflammatory disease characterized by the involvement of the axial skeleton. Alcohol consumption (AC) is a modifiable lifestyle…
  • Abstract Number: 0577 • ACR Convergence 2024

    AMH Titers in Women with Axial Spondyloarthritis Are Significantly Lower Compared to the General Population: An Analysis of the 10-year Follow-up of the DESIR Cohort

    Madeleine FRANC1, Jean Guibourdenche2, Anne Tournadre3 and Anna Molto4, 1Groupe Hospitalier Cochin, APHP, Paris, France, 2Groupe Hospitalier Cochin, APHP, Paris, 3Service de Rhumatologie, centre hospitalier universitaire de Clermont-Ferrand, Université Clermont Auvergne, Clermont-Ferrand, France, 4Groupe Hospitalier Cochin, AP-HP, Paris, France

    Background/Purpose: Data on fertility in women with spondyloarthritis (SpA) is sparse but seems to be impaired compared to the general population. Divergent results have been…
  • Abstract Number: 1011 • ACR Convergence 2024

    Use of the Shingrix Vaccine Among Patients with Inflammatory Arthritis and Risk of Cardiovascular Events Following Herpes Zoster

    Jeffrey Curtis1, Danielle M Conrad2, Whitney S Krueger2, Andrew P Gara2 and Kevin Winthrop3, 1FASTER Medicine, Hoover, AL, 2AbbVie, North Chicago, IL, 3School of Medicine, Oregon Health and Science University, Portland, OR

    Background/Purpose: The risk of herpes zoster (HZ) is increased in patients with inflammatory arthritis (IA); although the Shingrix vaccine has been available since 2017, its…
  • Abstract Number: 1445 • ACR Convergence 2024

    Systematic Characterization of MRI Lesions Per ASAS Definitions in the Sacroiliac Joints of Patients with Axial Spondyloarthritis and Comparisons Among Subgroups with Psoriasis, Iritis, Colitis, AxSpA Alone, and Matched Back Pain Controls

    Ulrich Weber1, Susanne Pedersen2, Ozun Bayindir Tsechelidis3, Robert Lambert4, Joel Paschke5, Stephanie Wichuk4 and Walter Maksymowych4, 1Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, 2Rigshospitalet, København, Denmark, 3Ottawa University, Ottawa, ON, Canada, 4University of Alberta, Edmonton, AB, Canada, 5CARE Arthritis, Edmonton, AB, Canada

    Background/Purpose: There is limited information on the frequency and topographical distribution of MRI lesions in the sacroiliac joints (SIJ) of patients with axSpA according to…
  • Abstract Number: 1758 • ACR Convergence 2024

    Minimal Spinal Radiographic Progression in Patients with Radiographic Axial Spondyloarthritis over 2 Years of Bimekizumab Treatment: Results from a Phase 3 Open-Label Extension Study

    Xenofon Baraliakos1, Sofia Ramiro2, Walter Maksymowych3, Mikkel Ostergaard4, Ute Massow5, Thomas Vaux6, Chetan Prajapati6, Alexander Marten5, Natasha de Peyrecave7 and Denis Poddubnyy8, 1Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 2Leiden University Medical Center, Bunde, Netherlands, 3University of Alberta, Edmonton, AB, Canada, 4Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark, 5UCB Pharma, Monheim am Rhein, Germany, 6UCB Pharma, Slough, United Kingdom, 7UCB Pharma, Brussels, Belgium, 8Charite-Universitatsmedizin Berlin, Berlin, Germany

    Background/Purpose: The effect of bimekizumab (BKZ), a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)‑17F in addition to IL-17A, on structural radiographic progression in the…
  • Abstract Number: 2347 • ACR Convergence 2024

    Drug Survival in Spondyloarthritis: Anti-IL17 Outperforms Anti-TNF in First Biologic Treatment

    Thao Pham1, Raphaëlle Curmin2, BENOIT FLACHAIRE3, Florence Tubach2 and Corinne MICELI4, 1Assistance Publique-Hôpitaux de Marseille, Marseille, France, 2Cephepi, Sorbonne Université, INSERM, APHP, Paris, Paris, France, 3Aix Marseille University, Marseille, France, 4Université de Paris Cité, APHP, Paris, France

    Background/Purpose: Drug survival rates serve as key indicators for assessing both the efficacy and safety of treatments in real life setting. Our aim was to…
  • Abstract Number: 0422 • ACR Convergence 2024

    Greater Use of Assisted Reproductive Techniques but Comparable Obstetric Morbidity in a Population of Women with Spondyloarthritis: A Matched Comparative Analysis of the GR2 Prospective Cohort and the French National Perinatal Surveys

    Sabrina Hamroun1, Grégoire Martin De Frémont2, Nathalie Costedoat-chalumeau3, Marion couderc4, René-Marc Flipo5, Jérémie Sellam6, Christophe Richez7, Rakiba Belkhir8, Laure Gossec9, Hubert Marotte10, Emmanuelle Dernis11, Aline Frazier12, Elisabeth Gervais13, Cedric Lukas14, Valerie Devauchelle15, Alban Deroux16, Véronique Le Guern17, Gaëlle Guettrot-Imbert18, Nathalie Lelong19, Camille Le Ray19, Raphaele Seror20 and Anna Molto21, and ENP 2021 and GR2 Study Groups, 1Cochin University Hospital, Paris, Ile-de-France, France, 2Le Kremlin-Bicêtre University Hospital, Le Kremlin-Bicêtre, Guyana, 3University Paris Cité, Paris, France, 4CHU de Clermont-Ferrand, Clermont-Ferrand, 5CHU Lille, Lille, Nord-Pas-de-Calais, France, 6Saint-Antoine Hospital - AP-HP, Paris, Ile-de-France, France, 7Pellegrin Hospital, Rheumatology, Referral Center for Rare Systemic Autoimmune and Autoinflammatory Diseases, Bordeaux, France, 8Service de Rhumatologie, Hôpital Bicêtre, AP-HP, Le Kremlin-Bicêtre, France, 9Sorbonne Université, Paris, France, 10Université Jean Monnet, CHU Saint-Etienne, Mines Saint-Etienne, INSERM SAINBIOSE 1059, Saint-Etienne, France, 11CH LE MANS, LE MANS, Pays de la Loire, France, 12Lariboisière University Hospital, Paris, France, 13University hospital, Poitiers, France, 14Rheumatology department, CHU Montpellier, Montpellier, France, 15UBO, Brest, France, 16Clinique Universitaire de Médecine Interne, Department of Internal Medicine, Grenoble University Hospital, Grenoble, France, 17APHP, Hôpital Cochin, Paris, 18Cochin Hospital, Paris, France, 19University of Paris, INSERM Obstetrical, Perinatal and Pediatric Epidemiology Research Team, Paris, France, 20Service de Rhumatologie, Hôpital Bicêtre, AP-HP, le Kremlin Bicetre, Ile-de-France, France, 21Groupe Hospitalier Cochin, AP-HP, Paris, France

    Background/Purpose: Spondyloarthritis (SpA) regularly affects women of childbearing age1. A higher obstetric morbidity in women with SpA is suggested in the literature in several countries,…
  • Abstract Number: 0556 • ACR Convergence 2024

    Disease Duration, Age and Clinical Features Related to Aortic Valve Sclerosis in Patients with Spondyloarthritis

    Asier García-Alija1, Hye Sang Park1, Patricia Moya1, Ana Laiz1, Carla Marco2, Albert Casals1, Concepcion Pitarch2, Cesar Diaz-Torné1, Berta Paula Magallares3, Ivan Castellvi Barranco1, Susana Fernández-Sánchez1, Andrea García-Guillen2, Jose Luis Tandaipan1, Helena Codes-Mendez1, Guillem Verdaguer1, Luis Sainz1 and Hèctor Corominas1, 1Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, 2Hospital Dos de Maig, Barcelona, Spain, 3Dept of Rheumatology, Hospital de la Santa Creu I Sant Pau, Barcelona, ES, Barcelona, Spain

    Background/Purpose: Valve degeneration is prevalent in Spondylarthritis (SpA) patients according to descriptive studies, but it is also common in general population. Disease burden may be…
  • Abstract Number: 0578 • ACR Convergence 2024

    Gender Differences in Disease Parameters, Adherence to Treat to Target Strategy and Outcomes in Axial Spondyloarthritis (axSpA) in Pakistani Cohort

    Muhammad Saeed1, HIna Ahmed2 and Aziza Ahmed3, and Arthritis Carte Foundation Faculty, 1Central Park Medical College, Arthritis Care Foundation, Lahore, Pakistan, 2Central Park Medical College, Lahore, Pakistan, 3Rashid Latif Medical College, Lahore, Pakistan

    Background/Purpose: In patients with Axial Spondyloarthritis (axSpA) there has been wide variability in terms of gender regarding disease characteristics as well as outcomes across different…
  • Abstract Number: 1020 • ACR Convergence 2024

    Health Inequalities Exist Between the United States and Europe for Patients with Axial Spondyloarthritis

    Elena Nikiphorou1, Alexis Ogdie2, Dan Twigg3, Emily Quiñones4, You-Li Ling5, Karim Masri6, Joseph C. Cappelleri7, Lidia Sanchez-Riera8, Megan Hughes9 and NICOLA MASSEY9, 1King's College London, London, United Kingdom, 2Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 3Adelphi Real World, Manchester, United Kingdom, 4Adelphi Real World, Macclesfield, United Kingdom, 5Pfizer Inc, New York, NY, 6Pfizer Inc, Collegeville, PA, 7Pfizer, Groton, 8Pfizer, Madrid, 9Adelphi Real World, Bollington, United Kingdom

    Background/Purpose: Structural differences exist between the healthcare systems in the United States (US) and Europe. In real-world clinical settings, we investigated whether these differences create…
  • Abstract Number: 1447 • ACR Convergence 2024

    The Frequency of Diffuse Idiopathic Skeletal Hyperostosis (DISH) in Spondyloarthritis in Comparison to Age and Sex-matched Controls and Impact of SpA on Onset Age of DISH

    Ummugulsum Gazel1, Nicole Hryciw2, Baljot Chahal3, Seyyid Bilal Acikgoz4, Gizem Ayan5, Zaid Jibri3, Marcos Loreto Sampaio3 and Sibel Aydin6, 1University of Ottawa, Ottawa, ON, Canada, 2University of Ottawa, Ottawa, Canada, 3University of Ottawa, Radiology, Ottawa, Canada, 4University of Ottawa, Rheumatology, Ottawa, ON, Canada, 5University of Ottawa, Rheumatology, Ankara, Turkey, 6University of Ottawa - Ottawa, Ottawa, ON, Canada

    Background/Purpose: Although diffuse idiopathic skeletal hyperostosis (DISH) is classically defined in the thoracic spine and the elderly population, there are case reports on the overlap…
  • Abstract Number: 1875 • ACR Convergence 2024

    Assessing the PULSAR (Program to Understand the Longterm Outcomes in Spondyloarthritis) Registry for Environmental Determinants of Heath Research

    Liya Stolyar1, Diane Mar2, Yuhan Liu3, Esther Velasquez4, orr Sharpe5, Michael Weisman6, Liron Caplan7 and suzanne Tamang8, 1Palo Alto VA Medical Center/Stanford, Stanford, CA, 2Palo Alto VA Medical Center/Stanford University Medical Center, Palo Alto, CA, 3Stanford Medicine Quantitative Sciences Unit, Palo Alto, CA, 4Stanford Center for Population Health Sciences, Palo Alto, CA, 5Department of Immunology and Rheumatology, Stanford University, Stanford, CA, 6Stanford University, Los Angeles, CA, 7Univ of Colorado School of Medicine/Rocky Mtn Regional Veterans Affairs Medical Center, Aurora, CO, 8Stanford University, Atherton, CA

    Background/Purpose: Acute exposure to air pollution has been associated with flares of psoriasis and chronic inflammatory arthritides in prior studies.  However, the impact of air pollution,…
  • Abstract Number: 2351 • ACR Convergence 2024

    Low Uveitis Rates in Patients with Axial Spondyloarthritis or Psoriatic Arthritis Treated with Bimekizumab: Long-Term Results from Phase 2b/3 Trials

    Irene E. van der Horst-Bruinsma1, Matthew A. Brown2, Floris van Gaalen3, Nigil Haroon4, Lianne S Gensler5, Alexander Marten6, Myriam Manente7, George Stojan8, Thomas Vaux9, Katy White9, Atul Deodhar10 and Martin Rudwaleit11, 1Department of Rheumatology, Radboud University Medical Centre, Nijmegen, Netherlands, 2Genomics England, London, United Kingdom, 3LUMC, Leiden, Zuid-Holland, Netherlands, 4Department of Medicine/Rheumatology, University Health Network, Schroeder Arthritis Institute, University of Toronto, Toronto, ON, Canada, 5Department of Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, 6UCB Pharma, Monheim am Rhein, Germany, 7UCB Pharma, Braine-l'Alleud, Belgium, 8UCB Pharma, Atlanta, GA, 9UCB Pharma, Slough, United Kingdom, 10Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR, 11University of Bielefeld, Klinikum Bielefeld, Bielefeld, Germany

    Background/Purpose: Acute anterior uveitis (‘uveitis’) is a common extra-musculoskeletal manifestation in patients (pts) with spondyloarthritis (SpA), and incidence varies with SpA type and disease duration.1,2,3…
  • Abstract Number: 0432 • ACR Convergence 2024

    Disease Activity During Pregnancy in Patients with Rheumatoid Arthritis or Spondyloarthritis: Results from the Multicentre Prospective GR2 Study

    Marion couderc1, celine lambert2, sabrina hamroun3, denis gallot4, Nathalie Costedoat-chalumeau5, Laure Gossec6, Gaëlle Guettrot-Imbert7, Veronique LE GUERN7, Christophe Richez8, MArtin Soubrier9 and Anna Molto10, 1CHU de Clermont-Ferrand, Clermont-Ferrand, 2chu clermont ferrand, clermont ferrand, France, 3Rheumatology Department - Cochin Hospital, Paris, France, 4Department of Obstetrics, CHU Clermont-ferrand, Clermont-Ferrand, Auvergne, France, 5University Paris Cité, Paris, France, 6Sorbonne Université, Paris, France, 7Cochin Hospital, Paris, France, 8Université de Bordeaux, Bordeaux, France, 9Gabriel-Montpied Hospital, Clermont-ferrand, France, 10Groupe Hospitalier Cochin, AP-HP, Paris, France

    Background/Purpose: Pregnancy may have a beneficial effect on disease activity in rheumatoid arthritis (RA) but the evidence is more conflicting in spondyloarthritis (SpA). The aim…
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