Abstracts tagged "Spondylarthropathies"

Abstract Number: 1202 • ACR Convergence 2020
Cannabis Use Assessment and Its Impact on Pain in Rheumatic Diseases: A Systematic Review and Meta-analysis
Manon Guillouard¹, Nicolas Authier¹, Bruno Pereira¹, Martin Soubrier¹ and Sylvain Mathieu¹, ¹CHU Gabriel Montpied, Clermont-Ferrand, France
Background/Purpose: Despite classic analgesic or effective treatments in rheumatic diseases, such as synthetic Disease Modifying Anti-Rheumatic Drugs in rheumatoid arthritis (RA), patients remain in pain…
Abstract Number: 1498 • ACR Convergence 2020
Pregnancy Outcomes in Patients with Axial Spondyloarthritis – a First Analysis of a European Collaboration of Pregnancy Registries
Yvette Meissner¹, Nathalie Costedoat-Chalumeau², Frauke Foerger³, Doreen Goll⁴, Anna Molto⁵, Rebecca Özdemir⁶, Marianne Wallenius⁷, Anja Strangfeld⁸ and Rebecca Fischer-Betz⁹, ¹Deutsches Rheuma-Forschungszentrum, Berlin, Germany, ²APHP, Université de Paris, Paris, France, ³University Hospital and University of Bern, Bern, Switzerland, Bern, Switzerland, ⁴Patient Research Partner, Berlin, Germany, ⁵Rheumatology Department, Cochin Hospital, Paris, Paris, France, ⁶Patient Research Partner, Duisburg, Germany, ⁷University Hospital and Norwegian University of Science and Technology, Trondheim, Norway, ⁸German Rheumatism Research Center, Berlin, Germany, ⁹Department of Rheumatology and Hiller Research Unit Rheumatology, Heinrich Heine University, Duesseldorf, Germany, Duesseldorf, Germany
Background/Purpose: Axial spondyloarthritis (axSpA) can affect women in their childbearing age. Data on pregnancy in axSpA patients are mainly retrospective and highly heterogeneous [1]. The…
Abstract Number: 2018 • ACR Convergence 2020
Development and Validation of an Artificial Intelligence Approach for the Detection of Radiographic Sacroiliitis
Keno-Kyrill Bressem¹, Janis Vahldiek¹, Lisa Adams¹, Stefan Niehues¹, Hildrun Haibel¹, Valeria Rios Rodriguez¹, Murat Torgutalp¹, Mikhail Protopopov¹, Fabian Proft¹, Judith Rademacher¹, Joachim Sieper¹, Martin Rudwaleit², Bernd Hamm¹, Markus Makowski¹, Kay-Geert Hermann¹ and Denis Poddubnyy³, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²Department of Internal Medicine and Rheumatology, Klinikum Bielefeld, Germany, ³Charité – Universitätsmedizin Berlin, Berlin, Germany
Background/Purpose: Conventional radiography of the sacroiliac joints is still recommended as the first imaging method if axial spondyloarthritis (axSpA) is suspected. Furthermore, radiographic sacroiliitis is…
Abstract Number: 1303 • ACR Convergence 2020
Performance of Three Referral Algorithms for Diagnosing Axial Spondyloarthritis: Results from the Screening in Axial Spondyloarthritis for Psoriasis, Iritis, and Colitis Cohort
Ulrich Weber¹, Raj Carmona², James Yeung³, Jon Chan⁴, Liam Martin⁵, Ariel Masetto⁶, Stephanie Keeling⁷, Olga Ziouzina⁵, Sherry Rohekar⁸, Rana Dadashova⁹, Joel Paschke⁹, Amanda Carapellucci⁹, Robert G Lambert¹⁰, Walter Maksymowych⁷ and Sibel Aydin¹¹, ¹University of South Denmark, Odense, Denmark, ²St. Joseph's Healthcare, Hamilton, ON, Canada, ³James Yeung Rheumatology, Vancouver, BC, Canada, ⁴Artus Health Clinic, Vancouver, BC, Canada, ⁵University of Calgary, Calgary, AB, Canada, ⁶University of Sherbrooke, Sherbrooke, QC, Canada, ⁷University of Alberta, Edmonton, AB, Canada, ⁸Lawson Health Research Institute, London, ON, Canada, ⁹CARE Arthritis, Edmonton, AB, Canada, ¹⁰University of Alberta and CARE Arthritis, Edmonton, AB, Canada, ¹¹University of Ottawa Faculty of Medicine, Rheumatology, Ottawa, ON, CANADA; The Ottawa Hospital Research Institute, Ottawa, ON, CANADA, Ottawa, ON, Canada
Background/Purpose: Patients presenting with back pain and psoriasis, acute anterior uveitis (AAU), or inflammatory bowel disease (IBD), represent a high-risk population for the presence of…
Abstract Number: 1521 • ACR Convergence 2020
A Novel Gut-joint Migratory TCRab+ Cell Subset Relies on sphingosine-1-phosphate for Tissue Localization
Adam Lefferts¹, Emilie Regner², Eric Norman³, David Claypool⁴, Hannah Schultz⁴, Danielle Sansone-Poe⁴ and Kristine Kuhn⁵, ¹University of Colorado, Anschutz Medical Campus, Aurora, CO, ²University of California San Francisco, San Francisco, CA, ³University of Colorado, Anschutz Medical Campus, Denver, ⁴University of Colorado, Anschutz Medical Campus, Aurora, ⁵University of Colorado Anschutz Medical Campus, Aurora, CO
Background/Purpose: Despite findings of similar immune cellular phenotypes in the gut and joint of patients with spondyloarthritis, the mechanistic linkage between intestinal immunology and the…
Abstract Number: 2025 • ACR Convergence 2020
Efficacy of Guselkumab, a Monoclonal Antibody That Specifically Binds to the p19 Subunit of IL-23, on Axial-Related Endpoints in Patients with Active PsA with Imaging-Confirmed Sacroiliitis: Week-52 Results from Two Phase 3, Randomized, Double-blind, Placebo-controlled Studies
Philip Mease¹, Philip Helliwell², Dafna Gladman³, Denis Poddubnyy⁴, Xenofon Baraliakos⁵, Soumya Chakravarty⁶, Alexa Kollmeier⁷, Elizabeth Hsia⁸, Xie Xu⁹, Shihong Sheng¹⁰, Prasheen Agarwal¹⁰, Bei Zhou¹⁰, May Shawi¹¹, Chetan Karyekar¹², Kristen Sweet¹⁰, Atul Deodhar¹³ and Désirée van der Heijde¹⁴, ¹Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, ²Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ³Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, ⁴Charité – Universitätsmedizin Berlin, Berlin, Germany, ⁵Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany, ⁶Janssen Scientific Affairs, LLC, Horsham, PA, USA and Drexel University College of Medicine, Horsham, PA, ⁷Janssen Research & Development, LLC, La Jolla, CA, ⁸Janssen Research & Development, LLC and University of Pennsylvania Medical Center, Spring House, PA, ⁹Janssen Research & Development, LLC, San Marcos, CA, ¹⁰Janssen Research & Development, LLC, Spring House, PA, ¹¹Janssen Global Services, LLC, Toronto, ON, Canada, ¹²Janssen Global Services, LLC, Horsham, PA, ¹³Oregon Health & Science University, Portland, OR, ¹⁴Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Guselkumab (GUS), an interleukin-23 inhibitor, improved axial symptoms of active psoriatic arthritis (PsA) through week 24 in a pooled analysis from two phase 3…
Abstract Number: 0058 • ACR Convergence 2020
Drug Retention and Discontinuation of Biological DMARDs and Novel Small Molecules: Data from the Singapore National Biologics Registry
Li Wearn Koh¹, Man Hua Aw², Preeti Dhanasekaran³, Rosa Lim Mui San¹, Stephanie Wong⁴, Xanthe Chua⁵, Wei Joo Choy¹, Manjari Lahiri⁶ and Siaw Ing Yeo², ¹Tan Tock Seng Hospital, Singapore, Singapore, ²Singapore General Hospital, Singapore, Singapore, ³National University of Singapore, Singapore, Singapore, ⁴Clinical Research and Innovation Office, Tan Tock Seng Hospital Singapore, Singapore, Singapore, ⁵Tan Tock Seng Hospital, Singapore, Singapore, Singapore, ⁶National University Hospital, Singapore, Singapore
Background/Purpose: To describe drug retention rate and reasons for discontinuation of biological disease modifying anti-rheumatic drugs ( bDMARD) and novel small molecules in patients from…
Abstract Number: 1304 • ACR Convergence 2020
Uveitis Occurrence in Early Inflammatory Back Pain: Five Years Data from a Prospective French Nationwide Cohort
Daniel Wendling¹, Clement Prati², Thierry Lequerre³, Corinne Miceli-Richard⁴, Maxime Dougados⁵, Anna Molto⁶ and Xavier Guillot⁷, ¹CHU Besançon, department of rheumatology, Besancon, France, ²Rheumatology, University Teaching Hospital, Besançon, France, ³Rheumatology, University Teaching Hospital, Rouen, France, ⁴Paris Descartes University, Department of Rheumatology - Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, ⁵Department of Rheumatology, Hopital Cochin, Université de Paris, Paris, France, ⁶Rheumatology Department, Cochin Hospital, APHP, Paris, France, Paris, France, ⁷CHU Reunion, Saint Denis, Reunion
Background/Purpose: Uveitis is the most frequent extra rheumatological manifestation in axial Spondyloarthritis (SpA). DESIR is a prospective multicenter cohort of patients with early inflammatory back…
Abstract Number: 1535 • ACR Convergence 2020
Frequency and Anatomic Distribution of Magnetic Resonance Imaging Lesions in the Sacro-iliac Joints of Healthy Subjects and Patients with Spondyloarthritis
Sophie Hecquet¹, Jean-Philippe Lustig², Frank Verhoeven¹, Mickaël Chouk¹, Sébastien Aubry², Daniel Wendling³ and Clement Prati¹, ¹Rheumatology, University Teaching Hospital, Besançon, France, ²Radiology, University Teaching Hospital, Besançon, France, ³CHU Besançon, department of rheumatology, Besancon, France
Background/Purpose: Lesions detected by magnetic resonance imaging (MRI) of the sacroiliac joints are critical to the diagnosis of non-radiographic axial spondyloarthritis. However, some lesions, such…
Abstract Number: 2028 • ACR Convergence 2020
Predictors of Maintaining Inactive Disease After Etanercept Withdrawal, and Regaining Inactive Disease Status After Flare and Retreatment, in Adults with Non-radiographic Axial Spondyloarthritis: Results from RE-EMBARK
Filip Van den Bosch¹, James Cheng-Chung Wei², Francisco Blanco³, Pamela Selema⁴, Daniela Graham⁵, Edmund Arthur⁶, Vassilis Tsekouras⁷, Bonnie Vlahos⁴, Chuanbo Zang⁴, Atul Deodhar⁸ and Peter Nash⁹, ¹Ghent University Hospital, Ghent, Belgium, ²Chung Shan Medical University Hospital, Taichung, Taiwan (Republic of China), ³INIBIC-Complejo Hospitalario Universitario A Coruña, A Coruna, Spain, ⁴Pfizer, Collegeville, PA, ⁵Pfizer, Groton, PA, ⁶Pfizer, Peapack, NJ, ⁷Pfizer, Nicosia, Cyprus, ⁸Oregon Health & Science University, Portland, OR, ⁹School of Medicine Griffith University, Brisbane, Queensland, Australia
Background/Purpose: RE-EMBARK was a phase 4, multicenter, open-label, 3-period study that evaluated etanercept (ETN) withdrawal and retreatment in adult patients with non-radiographic axial spondyloarthritis (nr-axSpA)…
Abstract Number: 0082 • ACR Convergence 2020
Diffuse Sclerosing Osteomyelitis of the Jaw: An Underdiagnosed Disease in Maxillofacial Surgery Department
Pauline Preuss¹, Hélios Bertin¹, Pierre Corre¹ and Benoit Le Goff², ¹Nantes University Hospital, Nantes, France, ²Nantes University Hospital, Nantes, Pays de la Loire, France
Background/Purpose: Diffuse sclerosing osteomyelitis of the jaw is a rare and under-recognized disease. Many authors include this diagnosis in the spectrum of aseptic osteitis sometimes…
Abstract Number: 1306 • ACR Convergence 2020
High Prevalence of Previously Undiagnosed Axial Spondyloarthritis in Patients Referred with Anterior Uveitis and Chronic Back Pain
Rianne van Bentum¹, Frank Verbraak², Sanne Wolf³, Maarten Boers⁴, Stevie Tan⁵ and Irene van der Horst-Bruinsma¹, ¹Department of Rheumatology, Amsterdam UMC, location VU University Medical Centre, Amsterdam, Netherlands, ²Amsterdam UMC, location VU University Medical Centre, Amsterdam, Netherlands, ³Amsterdam University Medical Center location VUmc, Amsterdam, Netherlands, ⁴Amsterdam Rheumatology and immunology Center | Reade and Amsterdam UMC, Amsterdam, Netherlands, ⁵Amsterdam University Medical Center, Amsterdam, Netherlands
Background/Purpose: To reduce the diagnostic delay in axial spondyloarthritis (axSpA), Rheumatology and Ophthalmology guidelines recommend to refer patients with acute anterior uveitis (AAU) and chronic…
Abstract Number: 1592 • ACR Convergence 2020
Improving Documentation of Smoking Cessation Counseling Among Spondyloarthropathy Smokers
Yusuf Chao¹, Jake Hutto², Elena Joerns², Rashmi Arora³, Una Makris¹ and Swathi Reddy³, ¹UT Southwestern Medical Center, Dallas, TX, ²Division of Rheumatic Diseases, UT Southwestern Medical Center, Dallas, TX, ³Veterans Affairs North Texas Healthcare System / UT Southwestern Medical Center, Dallas, TX
Background/Purpose: Smoking is prevalent among patients with spondyloarthropathies (SpA) and is associated with higher disease activity, poorer quality of life, and dampened response to biologic…
Abstract Number: 2030 • ACR Convergence 2020
Treatment with Selective Cyclooxygenase-2 Inhibitors Is Associated with Inhibition of Radiographic Spinal Progression in Patients with Axial Spondyloarthritis: Long-term Results from the German Spondyloarthritis Inception Cohort
Denis Poddubnyy¹, Valeria Rios Rodriguez², Murat Torgutalp², Ani Dilbaryan², Maryna Verba², Mikhail Protopopov², Fabian Proft², Judith Rademacher², Hildrun Haibel², Martin Rudwaleit³ and Joachim Sieper², ¹Charité – Universitätsmedizin Berlin, Berlin, Germany, ²Charité Universitätsmedizin Berlin, Berlin, Germany, ³Department of Internal Medicine and Rheumatology, Klinikum Bielefeld, Germany
Background/Purpose: There are conflicting data on the effect of non-steroidal anti-inflammatory drugs (NSAIDs) on radiographic spinal progression in axial spondyloarthritis (axSpA). One randomized controlled trial…
Abstract Number: 0100 • ACR Convergence 2020
Concordance Between the QuantiFERON-TB Gold In-Tube and Tuberculin Test for the Diagnosis of Latent Tuberculosis Infection in Patients with Rheumatic Diseases
Cristobal Pavez Perales¹, Ana Quiles Rocher², Elena Grau Garcia³, Marta De la Rubia Navarro¹, Samuel Leal Rodriguez⁴, Roxana Gonzalez Mazario¹, Jorge Juan Fragio Gil¹, Cristina Alcañiz Escandell³, Jose Ivorra Cortes¹, Inmaculada Chalmeta Verdejo¹, Luis Gonzalez Puig⁵, Isabel Martinez Cordellat¹, Rosa Negueroles Albuixech¹, Jose Eloy Oller Rodriguez¹, Francisco Miguel Ortiz Sanjuan⁴, Elvira Vicens Bernabeu⁴, Carmen Najera Herranz¹, Ines Canovas Olmos¹ and Jose Andres Roman Ivorra¹, ¹Rheumatology Department. HUP La Fe, Valencia, Spain, ²Medical School, UCV, Valencia, Valencia, Spain, ³Rheumatology Department. HUP La Fe, Valencia, Comunidad Valenciana, Spain, ⁴Rheumatology Department, HUP La Fe, Valencia, Spain, ⁵Rheumatology Department. HUP La Fe, Torrente ( Valencia), Spain
Background/Purpose: Patients with rheumatic diseases (RD) are at higher risk of latent tuberculosis infection (LTBI) reactivation. To detect and treat it before starting treatment, especially with biological therapies, decrease the reactivation risk. Diagnosis is carried…

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