Abstracts tagged "spondylarthritis and tissue remodeling"

Abstract Number: 2077 • 2018 ACR/ARHP Annual Meeting
Pathological Osteogenesis and Inflammation in Experimental Spondyloarthritis Are Associated with Aberrant Type H Blood Vessels and Development of High Endothelial Venules Accompanied By Ectopic Lymphoid Structures in Bone Marrow
Merlijn Kaaij¹, Jan Piet van Hamburg², George Kollias³, Dominique Baeten¹, Leonie van Duivenvoorde¹ and Sander W. Tas², ¹Department of Clinical Immunology & Rheumatology and Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, ²Amsterdam Rheumatology & immunology Center | Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, ³Department of Physiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece
Background/Purpose: Spondyloarthritis (SpA) is characterized by pathological osteogenesis, inflammation and extensive angiogenesis in inflamed tissues. TNF plays a central role in SpA pathology and transgenic…

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