Abstracts tagged "SNPs"

Abstract Number: 1017 • 2019 ACR/ARP Annual Meeting
The Integration of Genetic Data, Molecular Pathway Analysis and Differential Expression to Delineate the Impact of Ancestral Differences on Lupus
Katherine Owen¹, Bryce Aidukaitis ¹, Adam Labonte ¹, Michelle Catalina ¹, Prathyusha Bachali ¹, Nicholas Geraci ², Miranda Marion ³, Hannah Ainsworth ⁴, kip Zimmerman ³, Timothy Howard ⁴, Carl Langefeld ⁴, Peter Lipsky ² and Amrie Grammer ⁵, ¹AMPEL Biosolutions and the RILITE research institute, Charlottesville, VA, ²AMPEL BioSolutions, LLC, Charlottesville, VA, ³Wake Forest School of Medicine, Winston-Salem, NC, ⁴Wake Forest School of Medicine, Winston-Salem, ⁵AMPEL BioSolutions and RILITE Research Institute, Charlottesville, VA
Background/Purpose: Systemic lupus erythematosus (SLE) is a multi-organ autoimmune disorder with a prominent genetic component. Evidence has shown that individuals of African-Ancestry (AA) experience the…
Abstract Number: 1386 • 2012 ACR/ARHP Annual Meeting
Genetic Variation and Coronary Atherosclerosis in Patients with Systemic Lupus Erythematosus
Cecilia P. Chung¹, Joseph F. Solus², Annette Oeser³, Chun Li⁴, Paolo Raggi⁵, Jeffrey R. Smith³ and C. Michael Stein⁶, ¹Medicine, Vanderbilt University School of Medcine, Nashville, TN, ²Medicine, Vanderbilt University, Nashville, TN, ³Vanderbilt University, Nashville, TN, ⁴Biostatistics, Vanderbilt University, Nashville, TN, ⁵University of Alberta, Edmonton, AB, Canada, ⁶Internal Medicine and Pharmacology, Vanderbilt University, Nashville, TN
Background/Purpose: Premature coronary artery disease is a major cause of morbidity and mortality in patients with systemic lupus erythematosus (SLE). However, this is not explained…

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