ACR Meeting Abstracts

ACR Meeting Abstracts

Abstracts tagged "SLE and neuropsychiatric disorders"

  • Abstract Number: 1941 • ACR/ARHP Annual Meeting 2014

    Neuropsychiatric Lupus Is Substantially Unaffected By B-Cell Deficiency

    Jing Wen1, Ariel Stock2, Haowei Wang3, Mark Shlomchik3, Maria Gulinello2 and Chaim Putterman4, 1Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, 2Albert Einstein College of Medicine, Bronx, NY, 3University of Pittsburgh School of Medicine, Pittsburgh, PA, 4The Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY

    Background/Purpose: Neuropsychiatric lupus (NPSLE) is one of the earliest clinical manifestations in human lupus. However, its mechanisms are not fully understood. In lupus, a compromised…

  • Abstract Number: 664 • ACR/ARHP Annual Meeting 2014

    The Pathogenesis of Neuropsychiatric Systemic Lupus Erythematosus Is Dependent on Brain Intrinsic Factors

    Ariel Stock1, Jing Wen2, Jessica Doerner2 and Chaim Putterman3, 1Albert Einstein College of Medicine, Bronx, NY, 2Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, 3Rheumatology, Albert Einstein College of Medicine, Bronx, NY

    Background/Purpose: Neuropsychiatric disease is a common manifestation of systemic lupus erythematosus (SLE). Frequent presentations include depression, anxiety, memory loss and cognitive decline. The pathogenesis of…

  • Abstract Number: 1592 • ACR/ARHP Annual Meeting 2013

    “Lupus Headache”: Results From a Prospective, International, Inception Cohort Study

    John G. Hanly1, Murray B. Urowitz2, Aidan o'Keeffe3, Caroline Gordon4, Sang-Cheol Bae5, Jorge Sanchez-Guerrero6, Juanita Romero-Diaz7, Ann E. Clarke8, Sasha Bernatsky9, Daniel J. Wallace10, E.M. Ginzler11, David A. Isenberg12, Anisur Rahman13, Joan T. Merrill14, Michelle A. Petri15, Paul R. Fortin16, D. D. Gladman17, Barri J. Fessler18, Graciela S. Alarcon19, Ian N. Bruce20, Mary Anne Dooley21, Kristjan Steinsson22, Munther A. Khamashta23, Rosalind Ramsey-Goldman24, Susan Manzi25, Gunnar K. Sturfelt26, Ola Nived27, Asad A. Zoma28, R. F. van Vollenhoven29, Manuel Ramos-Casals30, Cynthia Aranow31, Meggan Mackay32, Guillermo Ruiz-Irastorza33, Kenneth C. Kalunian34, S. Sam Lim35, Murat Inanc36, Diane L. Kamen37, Christine Peschken38, Søren Jacobsen39, Chris Theriault40, Kara Thompson40 and Vernon Farewell3, 1Division of Rheumatology, Dalhousie University and Capital Health, Halifax, NS, Canada, 2Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3MRC Biostatistics Unit, Institute of Public Health, University Forvie Site, Cambridge, United Kingdom, 4School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom, 5Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 6UHN Toronto Western Hospital, Toronto, ON, Canada, 7Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 8Division of Rheumatology, University of Calgary, Alberta, Calgary, AB, Canada, 9Clinical Epidemiology, Research Institute of the McGill University Health Ctre, Montreal, QC, Canada, 10Cedars-Sinai Medical Center, Los Angeles, CA, 11Rheumatology, SUNY-Downstate Medical Center, Brooklyn, NY, 12Centre for Rheumatology Research, Rayne Building, 4th Floor, Centre for Rheumatology, Department of Medicine, University College London, London, United Kingdom, 13Centre for Rheumatology Research,Rayne Institute, 4th Floor, University College London, London, United Kingdom, 14Clinical Pharmacology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 15Johns Hopkins University School of Medicine, Baltimore, MD, 16Medicine, Centre de Recherche du Chu de Québec et Université Laval, Quebec City, QC, Canada, 17Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, 18Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, 19Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, 20Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit and NIHR Manchester Musculoskeletal Biomedical Research Unit, The University of Manchester, Manchester, United Kingdom, 21University of North Carolina at Chapel Hill, Chapel Hill, NC, 22Rheumatology, Landspital Univ Hospital, Reykjavik, Iceland, 23Lupus Research Unit, The Rayne Institute, St Thomas Hospital, Kings College London School of Medicine, London, United Kingdom, 24Medicine/Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 25Division of Rheumatology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 26Department of Rheumatology, University Hospital Lund, Lund, Sweden, 27Department of Clinical Science, Lund University, Rheumatology, Lund, Sweden, 28Rheumatology, Hairmyres Hospital, East Kilbride, United Kingdom, 29Clinical Trials Unit Department of Rheumatology, The Karolinska Institute, Stockholm, Sweden, 30Laboratorio de Enfermedades Autoinmunes Josep Font, Hospital Clínic, Barcelona, Spain, 31The Feinstein Institute, Manhasset, NY, 32Autoimmune & Musculoskeletal Disease, Feinstein Institute for Medical Research, Manhasset, NY, 33Autoimmune Diseases Research Unit, Department of Internal Medicine, BioCruces Health Research Institute, Hospital Universitario Cruces, University of the Basque Country, Barakaldo, Spain, 34UCSD School of Medicine, La Jolla, CA, 35Emory University School of Medicine, Division of Rheumatology, Atlanta, GA, 36Department of Internal Medicine, Rheumatology Division, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, 37Department of Medicine, Medical University of South Carolina, Charleston, SC, 38Medicine & Community Health Sciences, University of Manitoba, Winnipeg, MB, Canada, 39Department of Rheumatology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark, 40Department of Medicine, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada

    Background/Purpose: “Lupus headache” is controversial and is included in validated measures of global SLE disease activity. We examined the frequency and characteristics of “lupus headache”…

  • Abstract Number: 563 • ACR/ARHP Annual Meeting 2013

    Hold The Rituximab: Neuropsychiatric Disease In Murine Lupus Is Not B-Cell Dependent

    Jing Wen1, Ariel Stock1, Haowei Wang2, Mark Shlomchik2, Maria Gulinello1 and Chaim Putterman3, 1Albert Einstein College of Medicine, Bronx, NY, 2University of Pittsburgh School of Medicine, Pittsburgh, PA, 3The Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY

    Background/Purpose: Neuropsychiatric disease is one of the earliest clinical manifestations in systemic lupus erythematosus (SLE). However, the mechanisms leading to neuropsychiatric SLE (NPSLE) are not…