Abstracts tagged "SLE and nephritis"

Abstract Number: 1101 • 2018 ACR/ARHP Annual Meeting
Extracellular Vesicle-Mediated Delivery of EBV SMALL RNA (EBER1) Activates LUPUS Nephritis Related Antiviral Immunity in Tubular Epithelial CELLS VIA TLR3
R Baglio¹, M Tsang-A-Sjoe², M Eijndhoven¹, K Jordanova³, N Groenewegen¹, J van Weering⁴, S Verkuijlen¹, Irene E.M. Bultink⁵, J Middeldorp⁶, J Roelofs⁷, Alexandre Voskuyl⁸ and M Pegtel¹, ¹pathology, VU University medical center, Amsterdam, Netherlands, ²Rheumatology, Amsterdam Rheumatology and immunology Center | VU University Medical Center, Amsterdam, Netherlands, ³gynaecologic oncology, VU University medical center, Amsterdam, Netherlands, ⁴functional genomics, VU University medical center, Amsterdam, Netherlands, ⁵Rheumatology, Amsterdam Rheumatology and immunology Center | VU University Medical Center, Amsterdam, Netherlands, Amsterdam, Netherlands, ⁶pathology, VU Uninersity medical center, Amsterdam, Netherlands, ⁷pathology, Amsterdam Medical Center, Amsterdam, Netherlands, ⁸Amsterdam Rheumatology and immunology Center, Location VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: In lupus nephritis (LN), genetic and environmental factors drive the chronic activation of antiviral defenses leading to immune complex-mediated glomerular and tubular damage. Increasing…
Abstract Number: 3122 • 2015 ACR/ARHP Annual Meeting
A Longitudinal Analysis of Change in Lupus Nephritis in an International Inception Cohort Using a Multistate Markov Model Approach
John G. Hanly¹, Li Su², Murray Urowitz^3,4, Juanita Romero-Diaz⁵, C. Gordon⁶, Sang-Cheol Bae⁷, Sasha R Bernatsky⁸, Ann Clarke⁹, Daniel J Wallace¹⁰, Joan T. Merrill¹¹, David A. Isenberg¹², Anisur Rahman¹³, Ellen M. Ginzler¹⁴, Paul Fortin¹⁵, Dafna D. Gladman¹⁶, Jorge Sanchez-Guerrero¹⁷, Michelle Petri¹⁸, Ian N. Bruce¹⁹, Mary Anne Dooley²⁰, Rosalind Ramsey-Goldman²¹, Cynthia Aranow²², Graciela S. Alarcon²³, Barri J. Fessler²⁴, Kristján Steinsson²⁵, Ola Nived²⁶, Gunnar K. Sturfelt²⁷, Susan Manzi²⁸, Munther Khamashta²⁹, Ronald F. van Vollenhoven³⁰, Asad Zoma³¹, Guillermo Ruiz-Irastorza³², Manuel Ramos-Casals³³, S. Sam Lim³⁴, Thomas Stoll³⁵, Murat Inanc³⁶, Kenneth C. Kalunian³⁷, Diane L. Kamen³⁸, Peter Maddison³⁹, Christine A. Peschken⁴⁰, Søren Jacobsen⁴¹, Anca Askanase⁴², Chris Theriault⁴³, Kara Thompson⁴³ and Vernon Farewell⁴⁴, ¹Rheumatology, Division of Rheumatology, Capital Health and Dalhousie University, Halifax, NS, Canada, ²Nova Scotia Rehab Site, Division of Rheumatology, Capital Health and Dalhousie University, Halifax, NS, Canada, ³Rheumatology, TWH, Toronto, ON, Canada, ⁴Rheumatology, U of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁵Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico city, Mexico, ⁶School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom, ⁷Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ⁸Division of Rheumatolog, McGill Unversity Health Cener, Montreal, QC, Canada, ⁹Division of Rheumatology, Department of Medicine, University of Calgary, Calgary, AB, Canada, ¹⁰Cedars-Sinai Medical Center, West Hollywood, CA, ¹¹Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ¹²Rayne Institute, Centre for Rheumatology Research, UCL Division of Medicine, London, United Kingdom, ¹³Centre for Rheumatology Research, U College of London, London, United Kingdom, ¹⁴Medicine/Box 42, SUNY-Downstate, Brooklyn, NY, ¹⁵Medicine, Division of Rheumatology, Centre Hospitalier Universitaire de Quebec et Universite Laval, Quebec, QC, Canada, ¹⁶Department of Medicine, Division of Rheumatology, University of Toronto, Toronto, ON, Canada, ¹⁷Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, ¹⁸Rheumatology, Johns Hopkins University Hospital, Baltimore, MD, ¹⁹Stopford Building, Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, ²⁰UNC Kidney Centre, Chapel Hill, NC, ²¹Northwestern University Feinberg School of Medicine, Chicago, IL, ²²Feinstein Institute for Medical Research, Manhasset, NY, ²³Medicine, University of Alabama at Birmingham, Birmingham, AL, ²⁴UAB, Birmingham, AL, ²⁵Rheumatology, Univ. Hospital, Reykjavik, Iceland, ²⁶Rheumatology, Inst of Clinical sciences, Lund, Sweden, ²⁷Department of Rheumatology, Univ Hospital Lund, Lund, Sweden, ²⁸Rheumatology, Allegheny Health Network, Pittsburgh, PA, ²⁹Graham Hughes Lupus Research Laboratory, The Rayne Institute, St Thomas' Hospital, London, United Kingdom, ³⁰Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden, ³¹Rheumatology, Hairmyres Hospital, East Kilbride, United Kingdom, ³²Universidad del Pais Vasco, Servicio de Medicina Interna, Hospital de Cruces, Bizkaia, Spain, ³³Autoimmune Diseases, IDIBAPS, Hospital Clinic, Barcelona, Spain, ³⁴Emory University School of Medicine, Atlanta, GA, ³⁵Abteilung Rheumatologie/Rehab, Kantonsspital Schaffhausen, Schaffhausen, Switzerland, ³⁶Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ³⁷Center for Innovative Therapy, UCSD School of Medicine, La Jolla, CA, ³⁸Medicine, Medical University of South Carolina, Charleston, SC, ³⁹School of Sport, Health and Exercise Sciences, Bangor University, George Building, Bangor, Gwynedd, LL57 2PZ, UK., Bangor, United Kingdom, ⁴⁰Rheumatology, Univ of Manitoba, Winnipeg, MB, Canada, ⁴¹Rheumatology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark, ⁴²NYU School of Medicine, New York, NY, ⁴³Dept of Medicine, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada, ⁴⁴Medicine, Division of Rheumatology, Capital Health and Dalhousie University, Halifax, NS, Canada
Background/Purpose: Patients with lupus nephritis (LN) may have improvement or deterioration in renal status over time. To capture bidirectional change we used a reversible multistate…

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