Abstracts tagged "SLE and immunoglobulin (IG)"

Abstract Number: 42 • 2013 ACR/ARHP Annual Meeting
Inhibition Of B Cell Differentiation To The Plasmablast and Plasma Cell Lineage By CC-220, a Potent Modulator Of The Cereblon E3 Ubiquitin Ligase Complex
Peter Schafer¹, Lori Capone², Lei Wu¹ and Rajesh Chopra³, ¹Department of Translational Development, Celgene Corporation, Summit, NJ, ²Celgene Corporation, Summit, NJ, ³Translational Development, Celgene Corporation, Summit, NJ
Background/Purpose: CC-220 is an immunomodulatory compound which binds to the CUL4 family E3 ubiquitin ligase complex protein cereblon (CRBN) with high affinity and modulates the…

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Abstracts tagged "SLE and immunoglobulin (IG)"

Inhibition Of B Cell Differentiation To The Plasmablast and Plasma Cell Lineage By CC-220, a Potent Modulator Of The Cereblon E3 Ubiquitin Ligase Complex