Abstracts tagged "SLE and early incomplete SLE"

Abstract Number: 805 • 2015 ACR/ARHP Annual Meeting
Interferon Activity in Early and Established SLE: Interferon Score Is Lower in Early Disease and Not Seen without Antibodies to Extractable Nuclear Antigens
Alaa A A Mohamed^1,2,3, Md Yuzaiful Md Yusof^1,4, Yasser El-Sherbiny⁵, Paul Emery^5,6 and Edward M. Vital^2,5, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ³Rheumatology and Rhabilitation, Assiut University, Assiut, Egypt, ⁴NIHR Leeds Musculoskeletal Biomedical Research Unit,Leeds Teaching Hospital NHS Trust, Leeds University, Leeds, United Kingdom, ⁵Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds University, Leeds, United Kingdom, ⁶3. NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospital NHS Trust, Leeds University, Leeds, United Kingdom
Background/Purpose: SLE patients have increased expression of interferon-stimulated genes (ISG) and multiple autoantibodies. Some patients initially present with early incomplete SLE (E-ILE) with ANA but…

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