ACR Meeting Abstracts

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Abstracts tagged "skin and systemic lupus erythematosus (SLE)"

  • Abstract Number: 2757 • 2017 ACR/ARHP Annual Meeting

    Kidney and Skin Single-Cell RNA Sequencing in Lupus Nephritis Provides Mechanistic Insights and Novel Potential Biomarkers

    Evan Der1, Hemant Suryawanshi2, Saritha Ranabothu3, Beatrice Goilav4, H. Michael Belmont5, Peter M. Izmirly6, Nicole Bornkamp5, Nicole Jordan7, Tao Wang1, Ming Wu6, Judith A. James8, Joel M. Guthridge9, Soumya Raychaudhuri10, Thomas Tuschl11, Jill P. Buyon12 and Chaim Putterman13, 1Albert Einstein College of Medicine, Bronx, NY, 2The Rockefeller University, New York, NY, 3Nephrology, Children's Hospital at Montefiore, Bronx, NY, 4Albert Einstein College of Medicine/Montefiore Medical Center, New York, NY, 5Medicine, New York University School of Medicine, New York, NY, 6New York University School of Medicine, New York, NY, 7Montefiore Medical Center, New York, NY, 8Arthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 9Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 10Divisions of Genetics and Rheumatology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 11Rockefeller University, New York, NY, 12Rheumatology, New York University School of Medicine, New York, NY, 13Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, USA, Bronx, NY

    Background/Purpose: Classification and treatment decisions in lupus nephritis (LN) are largely based on renal histology. Single-cell RNAseq (scRNAseq) analysis may accurately differentiate types of renal…
  • Abstract Number: 1769 • 2015 ACR/ARHP Annual Meeting

    Role of Topical Administration of Peptidylarginine Deiminase  Inhibitors in Murine Lupus

    Erica Moore1, Huw Lewis2, Carolyne K. Smith1, Venkataraman Subramaniam3, Victoria Hoffmann4, Paul Thompson5 and Mariana J. Kaplan1, 1Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 2Immuno Inflammation, GSK, Stevenage, United Kingdom, 3University of Massachusetts, Boston, MA, 4ORS, National Institutes of Health, Bethesda, MD, 5University of Massachusetts, Worcester, MA

    Background/Purpose: Peptidylarginine deiminases (PADs), specifically PAD4,  have recently been implicated in the pathogenesis of systemic lupus erythematosus (SLE) through their role in citrullinating histones in…
  • Abstract Number: 1649 • 2014 ACR/ARHP Annual Meeting

    High Specificity of Skin Immunoglobulin Deposits for diagnosing SLE in Patients with Lupus Nephritis

    Marco Ulises Martinez-Martinez1, Maria Daniela De Avila2, Mario Perales3, Lourdes Baranda4, Susana Román Acosta5, Jaime Antonio Borjas García5 and Carlos Abud-Mendoza1, 1Unidad de Investigaciones Reumatológicas, Hospital Central & Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico, 2Regional Unit Rheumatology and Osteoporosis, Hospital Central y Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico, 3Regional Unit of Rheumatology and Osteoporosis, Hospital Central y Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico, 4Regional Unit of Rheumatology and Osteoposis, Hospital Central y Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico, 5Nephrology Department, Hospital Central y Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico

    Background/Purpose: Deposit of different classes of immunoglobulins is the main feature of lupus nephritis;1 because of its high specificity, a patient is classified as having…
  • Abstract Number: 2512 • 2013 ACR/ARHP Annual Meeting

    Smoking Is Associated With More Severe Skin Disease In Subjects With Moderate To Severe Systemic Lupus Erythematosus (SLE)

    Victoria P. Werth1, Munther A. Khamashta2, Gabor G. Illei3, Stephen Yoo3, Liangwei Wang4 and Warren Greth3, 1Department of Dermatology, Veteran Affairs Medical Center, Philadelphia, PA, 2Lupus Research Unit, The Rayne Institute, St Thomas Hospital, Kings College London School of Medicine, London, United Kingdom, 3Clinical Development, MedImmune, LLC, Gaithersburg, MD, 4Biostatistics, MedImmune, LLC, Gaithersburg, MD

    Background/Purpose: The influence of smoking on the severity of cutaneous manifestations in adults with moderate to severe SLE was assessed in an ongoing international, multi-center,…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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